MALT
O tecido linfoide associado às mucosas (MALT) é um componente essencial do sistema imunológico que protege as superfícies mucosas contra patógenos. O MALT inclui estruturas como as amígdalas, as placas de Peyer e o apêndice, que estão envolvidas na iniciação de respostas imunológicas aos antígenos encontrados nas superfícies mucosas. A pesquisa sobre o MALT é crucial para entender os mecanismos da imunidade mucosal e o desenvolvimento de vacinas e tratamentos para infecções mucosais. Na CymitQuimica, oferecemos uma gama de reagentes e ferramentas para apoiar sua pesquisa em imunologia mucosal, inflamação e doenças infecciosas.
Foram encontrados 23 produtos de "MALT"
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MLT-231
<p>MLT-231: potent MALT1 Inhibitor, IC50=9 nM; blocks BCL10 cleavage, IC50=160 nM; exhibits antitumor efficacy in mouse ABC-DLBCL model.</p>Cor e Forma:SolidMLT-985
CAS:<p>MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC 50 value of 3 nM.</p>Fórmula:C17H15Cl2N9O2Cor e Forma:SolidPeso molecular:448.27MALT1 inhibitor MI-2
CAS:<p>MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor.</p>Fórmula:C19H17Cl3N4O3Pureza:98% - 99.87%Cor e Forma:SolidPeso molecular:455.72Cladribine
CAS:<p>Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.</p>Fórmula:C10H12ClN5O3Pureza:99.58% - >99.99%Cor e Forma:White Crystalline SolidPeso molecular:285.69MLT-943
CAS:<p>MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. [1].</p>Fórmula:C16H14ClF3N6O2Pureza:99.72% - 99.82%Cor e Forma:SolidPeso molecular:414.77MLT-748
CAS:<p>MLT-748 is an effective, selective, and allosteric MALT1 inhibitor. It binds MALT1 in the allosteric Trp580 pocket (IC50: 5 nM).</p>Fórmula:C19H19Cl2N9O3Pureza:99.62%Cor e Forma:SolidPeso molecular:492.32(R)-MLT-985
CAS:<p>(R)-MLT-985 (compound 11) is a MALT1 protease inhibitor with IC50 of 3 nM, also blocking IL-2 in Jurkat cells and ABC-DLBCL cell growth.</p>Fórmula:C17H15Cl2N9O2Cor e Forma:SolidPeso molecular:448.27MALT1-IN-3
CAS:<p>MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.</p>Fórmula:C21H19F3N8O2Cor e Forma:SolidPeso molecular:472.42MALT1-IN-8
CAS:<p>MALT1-IN-8: potent MALT1 inhibitor, IC50=2 nM; hinders OCI-LY3 cells, IC50=1.16 μM; anticancer, from patent WO2018165385A1.</p>Fórmula:C20H15Cl2N7OCor e Forma:SolidPeso molecular:440.29MLT-747
CAS:<p>MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).</p>Fórmula:C20H21Cl2N7O3Cor e Forma:SolidPeso molecular:478.33Z-VRPR-FMK
CAS:<p>Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.</p>Fórmula:C31H49FN10O6Cor e Forma:SolidPeso molecular:676.78(R)-MALT1-IN-3
CAS:<p>(R)-MALT1-IN-3 (121) inhibits MALT1 protease (IC50: 20 nM) and IL6/IL10 in OCI-LY3 (IC50: 60/40 nM).</p>Fórmula:C21H19F3N8O2Cor e Forma:SolidPeso molecular:472.42JNJ-67856633
CAS:<p>JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease .</p>Fórmula:C20H11F6N5O2Pureza:99.87%Cor e Forma:SolidPeso molecular:467.32(R)-MALT1-IN-7
CAS:<p>(R)-MALT1-IN-7 (compound 142a) is a potent inhibitor of MALT1 protease and has potential for cancer research.</p>Fórmula:C19H17F3N8O2SCor e Forma:SolidPeso molecular:478.45MALT1-IN-9
CAS:<p>MALT1-IN-9: potent MALT1 protease inhibitor, IC50 <500 nM in Raji cells, significant anticancer effects.</p>Fórmula:C16H12ClF3N6OCor e Forma:SolidPeso molecular:396.75NVS-MALT1
CAS:<p>NVS-MALT1 is an allosteric inhibitor of MALT1 [1].</p>Fórmula:C24H27ClF3N5O4SCor e Forma:SolidPeso molecular:574.02MALT1-IN-7
CAS:<p>MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.</p>Fórmula:C19H17F3N8O2SCor e Forma:SolidPeso molecular:478.45MALT1-IN-6
CAS:<p>MALT1-IN-6 is a MALT1 protease inhibitor (Ki: 9 nM) that exhibits anticancer activity.</p>Fórmula:C18H12Cl2F3N9OCor e Forma:SolidPeso molecular:498.25RGT-068A
CAS:<p>RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .</p>Fórmula:C17H16ClN9O2Cor e Forma:SolidPeso molecular:413.82MALT1-IN-11
CAS:<p>MALT1-IN-11: MALT1 inhibitor, IC50 <10-100 nM, reduces IL10, for cancer/autoimmune research.</p>Fórmula:C20H16F4N8OCor e Forma:SolidPeso molecular:460.39
