Receptor IL
Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.
Foram encontrados 110 produtos de "Receptor IL"
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Stapokibart
CAS:Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα, blocking IL-4Rα-mediated signaling. It is used in studies of atopic dermatitis.Pureza:96.09% (SEC-HPLC) - 96.09% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.3 kDaMepolizumab
CAS:Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.Pureza:98% - 98%Cor e Forma:LiquidPeso molecular:146.24 kDaMyD88-IN-1
CAS:MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.Fórmula:C23H24N6O7SPureza:99.99%Cor e Forma:SoildPeso molecular:528.54Ref: TM-T77353
1mg52,00€5mg156,00€1mL*10mM (DMSO)170,00€10mg225,00€25mg374,00€50mg464,00€100mg660,00€500mg1.359,00€PF-06342674
PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.Cor e Forma:LiquidPeso molecular:145.14 kDaMacrophage-activating lipopeptide 2 TFA
Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist activates immune cell responses macrophages,Fórmula:C99H167N19O30S·xC2HF3O2Pureza:97.56%Cor e Forma:SolidPeso molecular:2135.56 (free base)Reslizumab
CAS:Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.Pureza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:N/ACNTO 607
CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.Pureza:98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.11 kDaY13g dihydrochloride
Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are
Fórmula:C16H25ClN2O4Pureza:97.81%Cor e Forma:SoildPeso molecular:344.83ABzOH
CAS:2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.
Fórmula:C12H10O2Pureza:99.43%Cor e Forma:SolidPeso molecular:186.21Anti-Mouse IL-4 Antibody (11B11)
Anti-Mouse IL-4 Antibody (11B11) is an inhibitory antibody targeting mouse IL-4, with the clone number 11B11.Pureza:99%Cor e Forma:Odour LiquidPeso molecular:150 kDaIL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Fórmula:C33H41FN6O4Pureza:99.46%Cor e Forma:SolidPeso molecular:604.71Anakinra
CAS:Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.Fórmula:C759H1186N208O232S10Pureza:95% - ≥95%Cor e Forma:SolidPeso molecular:17257.6Anti-Human IL-17A
CAS:Anti-Human IL-17A (Secukinumab H chain) is a human monoclonal antibody targeting IL-17A, offering high affinity and low immunogenicity for psoriasis.Pureza:98%Cor e Forma:LiquidPeso molecular:~150 kDaIL-17A inhibitor 1
CAS:IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.
Fórmula:C24H27F5N8O4Pureza:99.37% - 99.37%Cor e Forma:SolidPeso molecular:586.51GSK717
CAS:GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.
Fórmula:C28H28N4O2Pureza:97.34% - 99.01%Cor e Forma:SolidPeso molecular:452.55Suplatast (Tosilate)
CAS:Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.Fórmula:C23H33NO7S2Pureza:99.34% - 99.65%Cor e Forma:White Or Off-White CrystalsPeso molecular:499.64CP 424174
CAS:CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.Fórmula:C22H29ClN2O4SPureza:>99.99%Cor e Forma:SolidPeso molecular:452.99GIBH-130
CAS:GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.Fórmula:C20H20N6OPureza:99.52%Cor e Forma:SolidPeso molecular:360.41Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Fórmula:CH10Cl2Na2O10P2Pureza:98%Cor e Forma:SolidPeso molecular:360.92Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Cor e Forma:LiquidPeso molecular:147.93 kDa
