Receptor IL
Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.
Foram encontrados 110 produtos de "Receptor IL"
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VGX-1027
CAS:VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.Fórmula:C11H11NO3Pureza:99.54% - 99.86%Cor e Forma:SolidPeso molecular:205.21Apilimod
CAS:<p>Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.</p>Fórmula:C23H26N6O2Pureza:99.38% - 99.89%Cor e Forma:SolidPeso molecular:418.49IL-17A inhibitor 1
CAS:<p>IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.</p>Fórmula:C24H27F5N8O4Pureza:99.37% - 99.37%Cor e Forma:SolidPeso molecular:586.51Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Cor e Forma:LiquidPeso molecular:147.93 kDaApilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Fórmula:C25H34N6O8S2Pureza:99.51% - ≥95%Cor e Forma:SolidPeso molecular:610.7Lyn peptide inhibitor acetate
Potent, cell-permeable Lyn inhibitor; hinders IL-5 receptor signaling, vital for asthma/allergy research.Fórmula:C117H188N30O26Pureza:98%Cor e Forma:SolidPeso molecular:2430.98YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Fórmula:C22H21N3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:359.42RO2959 Hydrochloride
CAS:RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.Fórmula:C21H20ClF2N5OSPureza:99.24%Cor e Forma:SolidPeso molecular:463.93Brazikumab
CAS:Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:LiquidSatralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Pureza:95%Cor e Forma:LiquidSirukumab
CAS:Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.Pureza:>95%Cor e Forma:LiquidPeso molecular:144.6 (kDa)Tirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Pureza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:148.83 kDaBimekizumab
CAS:Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.Pureza:>99.99%Cor e Forma:LiquidInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Pureza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Cor e Forma:LiquidCasdozokitug
CAS:Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.Pureza:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)Cor e Forma:LiquidPicankibart
CAS:Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.Pureza:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidBempikibart
CAS:Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.Pureza:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)Cor e Forma:LiquidSapelizumab
Sapelizumab is a humanised antibody targeting IL-6Ra/CD126, huIgG2-type heavy chains and huκ-type light chains, IL-6 antagonist NMOSD.Peso molecular:~150 kDaLebrikizumab
CAS:Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.Pureza:95%Cor e Forma:LiquidAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Pureza:95%Cor e Forma:LiquidPeso molecular:146.07 kDa
