Receptor IL
Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.
Foram encontrados 110 produtos de "Receptor IL"
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Nidanilimab
CAS:<p>Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.</p>Pureza:> 95%Cor e Forma:SoildPeso molecular:150 kDaImsidolimab
CAS:Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.Pureza:99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)Cor e Forma:LiquidBRD6989
CAS:BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.Fórmula:C16H16N4Pureza:99.43%Cor e Forma:SolidPeso molecular:264.33Ref: TM-T14778
1mg35,00€5mg70,00€10mg97,00€25mg187,00€50mg283,00€100mg419,00€200mg607,00€1mL*10mM (DMSO)78,00€YQ128
CAS:YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.Fórmula:C27H29ClN2O4S2Pureza:99.89%Cor e Forma:SolidPeso molecular:545.11Ref: TM-T13375
1mg56,00€5mg119,00€10mg187,00€25mg305,00€50mg512,00€100mg738,00€1mL*10mM (DMSO)144,00€Abrezekimab
CAS:Abrezekimab (VR 942), a humanized antibody, blocks IL-13/IL-13Rα1, for asthma/lung disease study.Pureza:98.34% (SEC-HPLC) - 98.34% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:48.1 kDaOlokizumab
CAS:Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.Pureza:99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:LiquidIxekizumab
CAS:Ixekizumab: IgG4 antibody, neutralizes IL-17A (<3 pM), treats severe plaque psoriasis & arthritis.Pureza:98.86% (SEC-HPLC) - > 99.3% (SDS-PAGE); 95.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.2 kDaBriakinumab
CAS:Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.Pureza:>95%Cor e Forma:LiquidElsilimomab
CAS:Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.Pureza:>95%Cor e Forma:LiquidPerakizumab
CAS:Perakizumab (RG4934) is a humanized monoclonal antibody targeting IL-17A, used in the study of psoriatic arthritis and other autoimmune diseases.Pureza:95.28% (SEC-HPLC) - 99.66% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.8 kDaIL-15-IN-1
CAS:IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).Fórmula:C30H36N6O4SPureza:99.16%Cor e Forma:SolidPeso molecular:576.71Ref: TM-T11634
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)210,00€Dupilumab
CAS:Dupilumab (REGN-668) is a systemic immunomodulator for AD.Pureza:95.00% - >99.2%Cor e Forma:LiquidPeso molecular:149.8 kDaAnti-IL-6R Reference Antibody (Vobarilizumab-Fc)
CAS:Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.Pureza:>95%Cor e Forma:LiquidBermekimab
CAS:Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.Cor e Forma:LiquidPeso molecular:145.45 kDaSarilumab
CAS:Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.Pureza:97.4%Cor e Forma:LiquidPeso molecular:144.12 kDaXeligekimab
CAS:Xeligekimab (GR 1501) is a fully humanized monoclonal antibody that neutralizes IL-17A and has anti-inflammatory activity for the study of plaque psoriasis.Pureza:95%Cor e Forma:LiquidPeso molecular:147.34 kDaSiltuximab
CAS:Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.Pureza:100% (SEC-HPLC) - > 95%Cor e Forma:LiquidPeso molecular:144.98 kDaVunakizumab
CAS:Vunakizumab is a humanized IgGκ monoclonal antibody targeting IL-17A, often linked to interleukin 22 to form Vunakizumab-IL22.Pureza:95%Cor e Forma:LiquidPeso molecular:146.38 kDaOlamkicept
CAS:Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.Pureza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:93.14 kDaRisankizumab
CAS:Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.Pureza:SDS-PAGE:95.3%;SEC-HPLC:98.3%Cor e Forma:LiquidPeso molecular:145.85 kDa2-Benzothiazolamine
CAS:2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.Fórmula:C7H6N2SPureza:99.09% - 99.3%Cor e Forma:Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)Peso molecular:150.2Brodalumab
CAS:Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.Pureza:98.3%Cor e Forma:LiquidPeso molecular:144.06 kDaEnokizumab
CAS:<p>Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.23%Cor e Forma:LiquidPeso molecular:145.98 kDaPF-07038124 HCl
CAS:PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.Fórmula:C18H23BClNO4Pureza:97.34% - 99.13%Cor e Forma:SoildPeso molecular:363.64Ordesekimab
CAS:Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.12 kDaTildrakizumab
CAS:Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.Pureza:> 95%Cor e Forma:LiquidPeso molecular:144.44 kDaMirikizumab
CAS:Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).Pureza:98.41% (SEC-HPLC) - 98.41% (SEC-HPLC)Cor e Forma:LiquidLevilimab
CAS:Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.Pureza:97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:LiquidSpesolimab
CAS:Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.Pureza:> 95%Cor e Forma:LiquidPeso molecular:150 kDaMyD88-IN-1
CAS:MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.Fórmula:C23H24N6O7SPureza:99.99%Cor e Forma:SoildPeso molecular:528.54Ref: TM-T77353
1mg52,00€5mg156,00€10mg225,00€25mg374,00€50mg464,00€100mg660,00€500mg1.359,00€1mL*10mM (DMSO)170,00€Ziltivekimab
CAS:<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Pureza:95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:SoildTorudokimab
Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.Pureza:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Cor e Forma:Odour LiquidDaclizumab
CAS:Daclizumab (Zenapax), a humanized antibody, blocks IL-2 by targeting CD25, used in multiple sclerosis.Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Cor e Forma:LiquidPeso molecular:144.12 kDaPascolizumab
CAS:Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.Pureza:> 95%Cor e Forma:LiquidPeso molecular:147.18 kDaNosantine racemate
CAS:Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).Fórmula:C14H22N4O2Pureza:98%Cor e Forma:SolidPeso molecular:278.35Mepolizumab
CAS:Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.Pureza:98% - 98%Cor e Forma:LiquidGuselkumab
CAS:Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.Pureza:SDS-PAGE:95% SEC-HPLC:98.97%Cor e Forma:LiquidPeso molecular:144.8 kDaDectrekumab
CAS:Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.Pureza:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.27 kDaCanakinumab
CAS:<p>Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).</p>Pureza:98.8%Cor e Forma:LiquidPeso molecular:145.18 kDaAnti-inflammatory agent 42
CAS:Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.Fórmula:C20H12N2OSPureza:99.47%Cor e Forma:SolidPeso molecular:328.39Triphenyl phosphate
CAS:Triphenyl phosphate is an flame retardant and endocrine disruptor that activates MAO-A/ROS/NF-κB pathways, disrupting placental tryptophan metabolism.Fórmula:C18H15O4PPureza:99.94%Peso molecular:326.288Temtokibart
CAS:Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.Cor e Forma:LiquidPeso molecular:142.34 kDaPF-06342674
PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.Cor e Forma:LiquidPeso molecular:145.14 kDaMacrophage-activating lipopeptide 2 TFA
Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist activates immune cell responses macrophages,Fórmula:C99H167N19O30S·xC2HF3O2Pureza:97.56%Cor e Forma:SolidPeso molecular:2135.56 (free base)Reslizumab
CAS:Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.Pureza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:N/AStapokibart
CAS:Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα, blocking IL-4Rα-mediated signaling. It is used in studies of atopic dermatitis.Pureza:96.09% (SEC-HPLC) - 96.09% (SEC-HPLC)Cor e Forma:LiquidCNTO 607
<p>CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.</p>Pureza:98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:Odour LiquidY13g dihydrochloride
<p>Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are</p>Fórmula:C16H25ClN2O4Pureza:97.81%Cor e Forma:SoildPeso molecular:344.83ABzOH
CAS:<p>2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.</p>Fórmula:C12H10O2Pureza:99.43%Cor e Forma:SolidPeso molecular:186.21Anti-Mouse IL-4 Antibody (11B11)
Anti-Mouse IL-4 Antibody (11B11) is an inhibitory antibody targeting mouse IL-4, with the clone number 11B11.Pureza:99%Cor e Forma:Odour LiquidAnti-Human IL-17A
CAS:Anti-Human IL-17A (Secukinumab H chain) is a human monoclonal antibody targeting IL-17A, offering high affinity and low immunogenicity for psoriasis.Pureza:98%Cor e Forma:LiquidPeso molecular:151 kDaIL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Fórmula:C33H41FN6O4Pureza:99.46%Cor e Forma:SolidPeso molecular:604.71Anakinra
CAS:Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.Fórmula:C759H1186N208O232S10Pureza:95% - ≥95%Cor e Forma:SolidPeso molecular:17257.6Ossirene
CAS:Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Fórmula:C2H4Cl3O2Te·H4NPureza:≥98%Cor e Forma:SolidPeso molecular:312.05Ref: TM-T6761
2mg42,00€5mg62,00€10mg87,00€25mg145,00€50mg208,00€100mg309,00€200mg460,00€1mL*10mM (DMSO)70,00€IL-17A inhibitor 1
CAS:<p>IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.</p>Fórmula:C24H27F5N8O4Pureza:99.37% - 99.37%Cor e Forma:SolidPeso molecular:586.51Apilimod 2HCl
CAS:Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.Fórmula:C23H28Cl2N6O2Pureza:98.41%Cor e Forma:SolidPeso molecular:491.41GIBH-130
CAS:GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.Fórmula:C20H20N6OPureza:99.52%Cor e Forma:SolidPeso molecular:360.41VGX-1027
CAS:VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.Fórmula:C11H11NO3Pureza:99.54% - 99.86%Cor e Forma:SolidPeso molecular:205.21Apilimod
CAS:<p>Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.</p>Fórmula:C23H26N6O2Pureza:99.38% - 99.89%Cor e Forma:SolidPeso molecular:418.49Esonarimod
CAS:Esonarimod (KE-298) is an antirheumatic drug.Fórmula:C14H16O4SPureza:97.44%Cor e Forma:SolidPeso molecular:280.34Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Cor e Forma:LiquidPeso molecular:147.93 kDaSuplatast (Tosilate)
CAS:Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.Fórmula:C23H33NO7S2Pureza:99.34% - 99.65%Cor e Forma:White Or Off-White CrystalsPeso molecular:499.64RO2959 Hydrochloride
CAS:RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.Fórmula:C21H20ClF2N5OSPureza:99.24%Cor e Forma:SolidPeso molecular:463.93GSK717
CAS:<p>GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.</p>Fórmula:C28H28N4O2Pureza:97.34% - 99.01%Cor e Forma:SolidPeso molecular:452.55Apilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Fórmula:C25H34N6O8S2Pureza:99.51% - ≥95%Cor e Forma:SolidPeso molecular:610.7CP 424174
CAS:CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.Fórmula:C22H29ClN2O4SPureza:>99.99%Cor e Forma:SolidPeso molecular:452.99YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Fórmula:C22H21N3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:359.42Ref: TM-T3133
1mg35,00€2mg47,00€5mg69,00€10mg88,00€25mg160,00€50mg283,00€100mg399,00€1mL*10mM (DMSO)74,00€Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Fórmula:CH10Cl2Na2O10P2Pureza:98%Cor e Forma:SolidPeso molecular:360.92Sirukumab
CAS:Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.Pureza:>95%Cor e Forma:LiquidPeso molecular:144.6 (kDa)Satralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Pureza:95%Cor e Forma:LiquidBrazikumab
CAS:Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:LiquidPicankibart
CAS:Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.Pureza:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidBempikibart
CAS:Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.Pureza:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)Cor e Forma:LiquidAnti-Mouse IL-6R Antibody (15A7)
Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experimentsPureza:99% - 99%Cor e Forma:Odour LiquidSapelizumab
Sapelizumab is a humanised antibody targeting IL-6Ra/CD126, huIgG2-type heavy chains and huκ-type light chains, IL-6 antagonist NMOSD.Peso molecular:~150 kDaLebrikizumab
CAS:Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.Pureza:95%Cor e Forma:LiquidAnrukinzumab
CAS:Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.Pureza:95%Cor e Forma:LiquidPeso molecular:145.38 kDaAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Pureza:95%Cor e Forma:LiquidPeso molecular:146.07 kDaGevokizumab
CAS:Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.Pureza:95%Cor e Forma:LiquidPeso molecular:144.93 kDaEbdarokimab
CAS:Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.Pureza:95%Cor e Forma:LiquidZiralimumab
CAS:Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.Pureza:95%Cor e Forma:LiquidRademikibart
CAS:Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, withoutPureza:95%Cor e Forma:LiquidPeso molecular:143.54 kDaGumokimab
CAS:Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.Pureza:95%Cor e Forma:LiquidBimekizumab
CAS:Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.Pureza:>99.99%Cor e Forma:LiquidInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Pureza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Cor e Forma:LiquidManfidokimab
CAS:Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.Pureza:95%Cor e Forma:LiquidPeso molecular:~150 kDaCasdozokitug
CAS:Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.Pureza:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)Cor e Forma:LiquidTirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Pureza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:148.83 kDaLusvertikimab
CAS:Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.Pureza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:LiquidD228
CAS:D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).Fórmula:C22H28O12Pureza:99.91%Cor e Forma:SolidPeso molecular:484.45Vopikitug
CAS:Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.Pureza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Cor e Forma:LiquidEtokimab
CAS:<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Pureza:95%Cor e Forma:LiquidA-802715
CAS:A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases theFórmula:C16H26N4O3Pureza:96.29%Cor e Forma:SolidPeso molecular:322.4BI605906
CAS:<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Fórmula:C17H22F2N4O3S2Pureza:97.14%Cor e Forma:SolidPeso molecular:432.51IL-4-inhibitor-1
CAS:IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).Fórmula:C18H12FN3O2Pureza:99.53% - 99.89%Cor e Forma:SolidPeso molecular:321.31Ref: TM-T36527
1mg47,00€5mg175,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€1mL*10mM (DMSO)137,00€BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Fórmula:C18H15BrCl2N2O2Pureza:99.93%Cor e Forma:SolidPeso molecular:442.13Dersalazine
CAS:<p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>Fórmula:C35H32N6O4Pureza:99.62%Cor e Forma:SolidPeso molecular:600.67NO-prednisolone
CAS:NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.Fórmula:C29H33NO9Pureza:98.65%Cor e Forma:SolidPeso molecular:539.57Ref: TM-T19480
1mg49,00€5mg109,00€10mg170,00€25mg298,00€50mg423,00€100mg593,00€200mg785,00€1mL*10mM (DMSO)130,00€NFAT Transcription Factor Regulator-1
CAS:NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).Fórmula:C17H10F6N4O2Pureza:99.90%Cor e Forma:SolidPeso molecular:416.28Ref: TM-T12218
1mg47,00€5mg93,00€10mg142,00€25mg255,00€50mg378,00€100mg540,00€500mg1.074,00€1mL*10mM (DMSO)93,00€Resiniferatoxin
CAS:Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.Fórmula:C37H40O9Pureza:93.08% - 99.34%Cor e Forma:SolidPeso molecular:628.71LMT-28
CAS:LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.Fórmula:C17H29NO4Pureza:97.55%Cor e Forma:SolidPeso molecular:311.42IL-2-IN-1
CAS:IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.Fórmula:C17H12F6N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:418.29IL-17A antagonist 3
CAS:IL-17A antagonist 3 is an IL-17A antagonist.Fórmula:C33H33ClN6O4Pureza:98%Cor e Forma:SolidPeso molecular:613.11Netakimab
CAS:Netakimab (BCD 085) is a monoclonal antibody targeting interleukin-17A and can be used to study spondyloarthritis.Pureza:95%Cor e Forma:LiquidPeso molecular:145.74 kDaTMC353121
CAS:TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9).Fórmula:C32H42N6O3Pureza:≥98%Cor e Forma:SolidPeso molecular:558.71CVN293
CAS:CVN293 is a inhibitor of the potassium channel KCNK13,BBB,It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microgliaFórmula:C14H10FN7OPureza:99.50%Cor e Forma:SolidPeso molecular:311.27SP4206
CAS:SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)Fórmula:C30H37Cl2N7O6Pureza:98%Cor e Forma:SolidPeso molecular:662.56NDI-034858
CAS:NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseasesFórmula:C23H24N8O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:460.49α-Terpineol
CAS:<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Fórmula:C10H18OPureza:97.55%Cor e Forma:Colorless LiquidPeso molecular:154.25Di-O-methyldemethoxycurcumin
CAS:Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.Fórmula:C22H22O5Pureza:98%Cor e Forma:SolidPeso molecular:366.41
