Receptor IL
Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.
Foram encontrados 110 produtos de "Receptor IL"
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Anti-Human IL-17A
CAS:Anti-Human IL-17A (Secukinumab H chain) is a human monoclonal antibody targeting IL-17A, offering high affinity and low immunogenicity for psoriasis.Pureza:98%Cor e Forma:LiquidPeso molecular:151 kDaIL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Fórmula:C33H41FN6O4Pureza:99.46%Cor e Forma:SolidPeso molecular:604.71Anakinra
CAS:Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.Fórmula:C759H1186N208O232S10Pureza:95% - ≥95%Cor e Forma:SolidPeso molecular:17257.6Ossirene
CAS:Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Fórmula:C2H4Cl3O2Te·H4NPureza:≥98%Cor e Forma:SolidPeso molecular:312.05Ref: TM-T6761
2mg42,00€5mg62,00€10mg87,00€25mg145,00€50mg208,00€100mg309,00€200mg460,00€1mL*10mM (DMSO)70,00€IL-17A inhibitor 1
CAS:<p>IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.</p>Fórmula:C24H27F5N8O4Pureza:99.37% - 99.37%Cor e Forma:SolidPeso molecular:586.51Apilimod 2HCl
CAS:Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.Fórmula:C23H28Cl2N6O2Pureza:98.41%Cor e Forma:SolidPeso molecular:491.41GIBH-130
CAS:GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.Fórmula:C20H20N6OPureza:99.52%Cor e Forma:SolidPeso molecular:360.41VGX-1027
CAS:VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.Fórmula:C11H11NO3Pureza:99.54% - 99.86%Cor e Forma:SolidPeso molecular:205.21Apilimod
CAS:<p>Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.</p>Fórmula:C23H26N6O2Pureza:99.38% - 99.89%Cor e Forma:SolidPeso molecular:418.49Esonarimod
CAS:Esonarimod (KE-298) is an antirheumatic drug.Fórmula:C14H16O4SPureza:97.44%Cor e Forma:SolidPeso molecular:280.34Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Cor e Forma:LiquidPeso molecular:147.93 kDaSuplatast (Tosilate)
CAS:Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.Fórmula:C23H33NO7S2Pureza:99.34% - 99.65%Cor e Forma:White Or Off-White CrystalsPeso molecular:499.64RO2959 Hydrochloride
CAS:RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.Fórmula:C21H20ClF2N5OSPureza:99.24%Cor e Forma:SolidPeso molecular:463.93GSK717
CAS:<p>GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.</p>Fórmula:C28H28N4O2Pureza:97.34% - 99.01%Cor e Forma:SolidPeso molecular:452.55Apilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Fórmula:C25H34N6O8S2Pureza:99.51% - ≥95%Cor e Forma:SolidPeso molecular:610.7CP 424174
CAS:CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.Fórmula:C22H29ClN2O4SPureza:>99.99%Cor e Forma:SolidPeso molecular:452.99YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Fórmula:C22H21N3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:359.42Ref: TM-T3133
1mg35,00€2mg47,00€5mg69,00€10mg88,00€25mg160,00€50mg283,00€100mg399,00€1mL*10mM (DMSO)74,00€Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Fórmula:CH10Cl2Na2O10P2Pureza:98%Cor e Forma:SolidPeso molecular:360.92Sirukumab
CAS:Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.Pureza:>95%Cor e Forma:LiquidPeso molecular:144.6 (kDa)Satralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Pureza:95%Cor e Forma:LiquidBrazikumab
CAS:Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:LiquidPicankibart
CAS:Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.Pureza:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidBempikibart
CAS:Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.Pureza:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)Cor e Forma:LiquidAnti-Mouse IL-6R Antibody (15A7)
Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experimentsPureza:99% - 99%Cor e Forma:Odour LiquidSapelizumab
Sapelizumab is a humanised antibody targeting IL-6Ra/CD126, huIgG2-type heavy chains and huκ-type light chains, IL-6 antagonist NMOSD.Peso molecular:~150 kDaLebrikizumab
CAS:Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.Pureza:95%Cor e Forma:LiquidAnrukinzumab
CAS:Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.Pureza:95%Cor e Forma:LiquidPeso molecular:145.38 kDaAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Pureza:95%Cor e Forma:LiquidPeso molecular:146.07 kDaGevokizumab
CAS:Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.Pureza:95%Cor e Forma:LiquidPeso molecular:144.93 kDaEbdarokimab
CAS:Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.Pureza:95%Cor e Forma:LiquidZiralimumab
CAS:Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.Pureza:95%Cor e Forma:LiquidRademikibart
CAS:Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, withoutPureza:95%Cor e Forma:LiquidPeso molecular:143.54 kDaGumokimab
CAS:Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.Pureza:95%Cor e Forma:LiquidBimekizumab
CAS:Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.Pureza:>99.99%Cor e Forma:LiquidInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Pureza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Cor e Forma:LiquidManfidokimab
CAS:Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.Pureza:95%Cor e Forma:LiquidPeso molecular:~150 kDaCasdozokitug
CAS:Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.Pureza:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)Cor e Forma:LiquidTirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Pureza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:148.83 kDaLusvertikimab
CAS:Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.Pureza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:LiquidD228
CAS:D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).Fórmula:C22H28O12Pureza:99.91%Cor e Forma:SolidPeso molecular:484.45Vopikitug
CAS:Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.Pureza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Cor e Forma:LiquidEtokimab
CAS:<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Pureza:95%Cor e Forma:LiquidA-802715
CAS:A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases theFórmula:C16H26N4O3Pureza:96.29%Cor e Forma:SolidPeso molecular:322.4BI605906
CAS:<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Fórmula:C17H22F2N4O3S2Pureza:97.14%Cor e Forma:SolidPeso molecular:432.51IL-4-inhibitor-1
CAS:IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).Fórmula:C18H12FN3O2Pureza:99.53% - 99.89%Cor e Forma:SolidPeso molecular:321.31Ref: TM-T36527
1mg47,00€5mg175,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€1mL*10mM (DMSO)137,00€BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Fórmula:C18H15BrCl2N2O2Pureza:99.93%Cor e Forma:SolidPeso molecular:442.13Dersalazine
CAS:<p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>Fórmula:C35H32N6O4Pureza:99.62%Cor e Forma:SolidPeso molecular:600.67NO-prednisolone
CAS:NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.Fórmula:C29H33NO9Pureza:98.65%Cor e Forma:SolidPeso molecular:539.57Ref: TM-T19480
1mg49,00€5mg109,00€10mg170,00€25mg298,00€50mg423,00€100mg593,00€200mg785,00€1mL*10mM (DMSO)130,00€NFAT Transcription Factor Regulator-1
CAS:NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).Fórmula:C17H10F6N4O2Pureza:99.90%Cor e Forma:SolidPeso molecular:416.28Ref: TM-T12218
1mg47,00€5mg93,00€10mg142,00€25mg255,00€50mg378,00€100mg540,00€500mg1.074,00€1mL*10mM (DMSO)93,00€Resiniferatoxin
CAS:Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.Fórmula:C37H40O9Pureza:93.08% - 99.34%Cor e Forma:SolidPeso molecular:628.71
