MAPK
As MAPKs são uma família de proteínas quinases envolvidas em uma variedade de processos celulares, incluindo crescimento, proliferação, diferenciação e respostas ao estresse. A via de sinalização MAPK consiste em várias camadas, incluindo ERK, JNK e p38 MAPKs, cada uma desempenhando papéis distintos na função celular. A desregulação da sinalização MAPK está ligada ao câncer, doenças inflamatórias e distúrbios metabólicos. Na CymitQuimica, oferecemos uma ampla gama de inibidores e ativadores de MAPK para apoiar sua pesquisa em biologia celular, transdução de sinais e mecanismos de doenças.
Foram encontrados 881 produtos de "MAPK"
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TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Fórmula:C24H21N3OSPureza:99.83%Cor e Forma:SolidPeso molecular:399.51Talmapimod
CAS:<p>Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.</p>Fórmula:C27H30ClFN4O3Pureza:98% - 99.9%Cor e Forma:SolidPeso molecular:513Encorafenib
CAS:Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.Fórmula:C22H27ClFN7O4SPureza:99.51% - 99.83%Cor e Forma:SolidPeso molecular:540.011588-A4
CAS:<p>1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.</p>Fórmula:C17H19BrClFN4O2Pureza:98.59%Cor e Forma:SolidPeso molecular:445.71PF-06260933
CAS:<p>PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.</p>Fórmula:C16H13ClN4Pureza:99.63% - 99.97%Cor e Forma:SolidPeso molecular:296.75AS601245
CAS:<p>AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.</p>Fórmula:C20H16N6SPureza:98% - 99.02%Cor e Forma:SolidPeso molecular:372.45Varenicline Tartrate
CAS:<p>Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.</p>Fórmula:C13H13N3·C4H6O6Pureza:98.23% - 98.32%Cor e Forma:Tan SolidPeso molecular:361.35Bentamapimod
CAS:<p>Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK.</p>Fórmula:C25H23N5O2SPureza:97.04% - 99.92%Cor e Forma:SolidPeso molecular:457.55CCT196969
CAS:<p>CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.</p>Fórmula:C27H24FN7O3Pureza:98.93% - 99.65%Cor e Forma:SolidPeso molecular:513.52XMD17-109
CAS:<p>XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).</p>Fórmula:C36H46N8O3Pureza:98.75% - 99.7%Cor e Forma:SolidPeso molecular:638.8Ulixertinib
CAS:<p>Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.</p>Fórmula:C21H22Cl2N4O2Pureza:99.31% - 99.95%Cor e Forma:SolidPeso molecular:433.33Adagrasib
CAS:<p>View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.</p>Fórmula:C32H35ClFN7O2Pureza:99.10% - 99.9%Cor e Forma:SolidPeso molecular:604.12Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Fórmula:C15H12O5Pureza:98.76% - >99.99%Cor e Forma:SolidPeso molecular:272.25D-JNKI-1 acetate
<p>D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.</p>Fórmula:C166H290N66O42Pureza:99.48%Cor e Forma:SolidPeso molecular:3882.5Cefotetan
CAS:<p>Cefotetan, a cephamycin antibiotic, fights various bacteria by disrupting cell wall synthesis.</p>Fórmula:C17H17N7O8S4Pureza:95.72% - 99.38%Cor e Forma:SolidPeso molecular:575.62β-Glycerophosphate disodium salt pentahydrate
CAS:β-Glycerophosphate disodium salt pentahydrate is a protein phosphatase inhibitor.Fórmula:C3H7O6PH2ONaPureza:98.94% - ≥98%Cor e Forma:SolidPeso molecular:306.11TAK-733
CAS:<p>TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.</p>Fórmula:C17H15F2IN4O4Pureza:98.31% - 99.53%Cor e Forma:SolidPeso molecular:504.23MRTX1133
CAS:<p>View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.</p>Fórmula:C33H31F3N6O2Pureza:97.39% - 99.6%Cor e Forma:SolidPeso molecular:600.63Pyridoxal 5'-phosphate hydrate
CAS:<p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>Fórmula:C8H10NO6PPureza:97.52%Cor e Forma:SolidPeso molecular:247.14GSK-114
CAS:<p>GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.</p>Fórmula:C19H23N5O4SPureza:99.51%Cor e Forma:SolidPeso molecular:417.48
