Ras
As proteínas Ras são pequenas GTPases que atuam como interruptores moleculares na via de sinalização MAPK, controlando o crescimento, a diferenciação e a sobrevivência celular. Ras ativado inicia uma cascata de sinalização que inclui Raf, MEK e ERK, levando a várias respostas celulares. As mutações nos genes Ras são comuns em cânceres, tornando Ras um foco importante da pesquisa sobre o câncer. Na CymitQuimica, oferecemos uma variedade de moduladores de Ras para apoiar sua pesquisa em biologia do câncer, transdução de sinais e desenvolvimento terapêutico.
Foram encontrados 167 produtos para "Ras".
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MAPK Inhibitor Library
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;Cor e Forma:Odour SolidRef: TM-L1400
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarMC 976
CAS:MC 976 is a derivative of Vitamin D3.Fórmula:C27H42O3Pureza:98%Cor e Forma:SolidPeso molecular:414.63GGTI298 Trifluoroacetate
CAS:GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and induces apoptosis.Fórmula:C27H33N3O3S·C2HF3O2Pureza:98.07% - >99.99%Cor e Forma:SolidPeso molecular:593.66KS-58
CAS:KS-58 is a derivative of KRpep-2d. It acts as an inhibitory peptide for K-Ras(G12D), selectively binding to K-Ras. KS-58 is capable of penetrating cells and interrupts the interaction between intracellular Ras and effector proteins. It inhibits the proliferation of tumor cells and exhibits antitumor activity.Fórmula:C64H89FN12O14S2Cor e Forma:SolidPeso molecular:1333.59TAT-PAK18 R192A
TAT-PAK18 R192A is an inactive Tat-Pak peptide. It does not influence Rac1 translocation triggered by any tested proteins.Fórmula:C143H247N55O37Peso molecular:3326.91369MRTF-A-IN-1
MRTF-A-IN-1 (compound 14) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.Fórmula:C22H21N3Cor e Forma:SolidPeso molecular:327.42ASP6918
ASP6918 is a potent, orally active KRAS G12C inhibitor with an IC50 of 0.028 µM. It inhibits cell growth and demonstrates antitumor activity.Fórmula:C36H43N7O3Cor e Forma:SolidPeso molecular:621.34274Sevelamer Carbonate
CAS:Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.Fórmula:(C3H7N·C3H5ClO)x·xH2CO3Pureza:98%Cor e Forma:Yellow SolidPeso molecular:211.64FTI-277 hydrochloride
CAS:FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.Fórmula:C22H30ClN3O3S2Pureza:97.57% - 97.61%Cor e Forma:SolidPeso molecular:484.07Ref: TM-T2700
1mg50,00€2mg70,00€5mg90,00€1mL*10mM (DMSO)102,00€10mg158,00€25mg304,00€50mg497,00€100mg708,00€200mg964,00€APS6-45
CAS:APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Fórmula:C23H16F8N4O3Pureza:99.39%Cor e Forma:White SolidPeso molecular:548.39Ref: TM-T8843
2mg37,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg120,00€25mg236,00€50mg380,00€100mg583,00€200mg785,00€RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Fórmula:C25H20N4O3Pureza:98.44% - 99.81%Cor e Forma:White SolidPeso molecular:424.45Ref: TM-T6634
1mg46,00€1mL*10mM (DMSO)92,00€5mg96,00€10mg147,00€25mg281,00€50mg447,00€100mg650,00€200mg888,00€ZT-12-037-01
CAS:Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).Fórmula:C21H31N5O2Pureza:99.56%Cor e Forma:White SolidPeso molecular:385.5(Rac)-Antineoplaston A10
CAS:Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Fórmula:C13H14N2O3Pureza:98.41%Cor e Forma:White SolidPeso molecular:246.26Ref: TM-T5379
1mg38,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg122,00€25mg198,00€50mg295,00€100mg424,00€200mg593,00€SCH54292
CAS:SCH-54292 is a GDP exchange inhibitor.Fórmula:C24H28N2O9SPureza:95.65%Cor e Forma:SolidPeso molecular:520.55ARS-1620
CAS:ARS-1620 is a covalent inhibitor of K-RASG12C.Fórmula:C21H17ClF2N4O2Pureza:98.86%Cor e Forma:White SolidPeso molecular:430.84Kobe0065
CAS:Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.Fórmula:C15H11ClF3N5O4SPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:449.79ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Fórmula:C22H21N3O3SPureza:99.36% - 99.56%Cor e Forma:SolidPeso molecular:407.49Ref: TM-T2463
1mg37,00€2mg52,00€5mg69,00€1mL*10mM (DMSO)71,00€10mg101,00€25mg200,00€50mg321,00€100mg515,00€Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Fórmula:C20H20Cl2N6OPureza:97.51% - 98.92%Cor e Forma:SolidPeso molecular:431.3181A-116
CAS:1A-116 is a specific Rac1 inhibitor.Fórmula:C16H16F3N3Pureza:99.71%Cor e Forma:SolidPeso molecular:307.31Ref: TM-T14004
1mg52,00€5mg105,00€1mL*10mM (DMSO)116,00€10mg158,00€25mg268,00€50mg421,00€100mg620,00€200mg875,00€BAY-293
CAS:BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).Fórmula:C25H28N4O2SPureza:97.16%Cor e Forma:SolidPeso molecular:448.58Ref: TM-T5418
1mg50,00€5mg105,00€1mL*10mM (DMSO)116,00€10mg177,00€25mg321,00€50mg482,00€100mg710,00€200mg982,00€
