Ras
As proteínas Ras são pequenas GTPases que atuam como interruptores moleculares na via de sinalização MAPK, controlando o crescimento, a diferenciação e a sobrevivência celular. Ras ativado inicia uma cascata de sinalização que inclui Raf, MEK e ERK, levando a várias respostas celulares. As mutações nos genes Ras são comuns em cânceres, tornando Ras um foco importante da pesquisa sobre o câncer. Na CymitQuimica, oferecemos uma variedade de moduladores de Ras para apoiar sua pesquisa em biologia do câncer, transdução de sinais e desenvolvimento terapêutico.
Foram encontrados 155 produtos de "Ras"
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MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Fórmula:C15H9NO3Pureza:98.6%Cor e Forma:SolidPeso molecular:251.24K-Ras(G12C) inhibitor 9
CAS:<p>K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Fórmula:C16H21ClIN3O4SPureza:97.33% - 97.45%Cor e Forma:SolidPeso molecular:513.78ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Fórmula:C22H29ClN4O3Pureza:97.43% - 98.4%Cor e Forma:SolidPeso molecular:432.94Antineoplaston A10
CAS:<p>Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.</p>Fórmula:C13H14N2O3Pureza:99.42%Cor e Forma:SolidPeso molecular:246.26ZCL278
CAS:<p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>Fórmula:C21H19BrClN5O4S2Pureza:96.29% - 99.72%Cor e Forma:SolidPeso molecular:584.89EHop-016
CAS:<p>EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.</p>Fórmula:C25H30N6OPureza:98.99% - >99.99%Cor e Forma:SolidPeso molecular:430.55Phellodendrine chloride
CAS:<p>Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.</p>Fórmula:C20H24ClNO4Pureza:98.85% - 99.05%Cor e Forma:SolidPeso molecular:377.86Y16
CAS:<p>Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.</p>Fórmula:C24H20N2O3Pureza:98.26% - 99.32%Cor e Forma:SolidPeso molecular:384.43CID-1067700
CAS:<p>CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).</p>Fórmula:C18H18N2O4S2Pureza:99.46%Cor e Forma:SolidPeso molecular:390.48FTI-277 hydrochloride
CAS:<p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>Fórmula:C22H30ClN3O3S2Pureza:97.57% - 97.61%Cor e Forma:SolidPeso molecular:484.07CCG-100602
CAS:<p>CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).</p>Fórmula:C21H17ClF6N2O2Pureza:99.58%Cor e Forma:SolidPeso molecular:478.82ARS-1620
CAS:<p>ARS-1620 is a covalent inhibitor of K-RASG12C.</p>Fórmula:C21H17ClF2N4O2Pureza:98.86%Cor e Forma:SolidPeso molecular:430.84(S)-AMG-510
CAS:<p>(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.</p>Fórmula:C30H30F2N6O3Pureza:99.05% - 99.76%Cor e Forma:SolidPeso molecular:560.594BAY-293
CAS:<p>BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).</p>Fórmula:C25H28N4O2SPureza:97.16%Cor e Forma:SolidPeso molecular:448.58ZT-12-037-01
CAS:<p>Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).</p>Fórmula:C21H31N5O2Pureza:99.56%Cor e Forma:SolidPeso molecular:385.5SCH54292
CAS:<p>SCH-54292 is a GDP exchange inhibitor.</p>Fórmula:C24H28N2O9SPureza:95.65%Cor e Forma:SolidPeso molecular:520.55APS6-45
CAS:<p>APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.</p>Fórmula:C23H16F8N4O3Pureza:99.39%Cor e Forma:SolidPeso molecular:548.39RBC8
CAS:<p>RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.</p>Fórmula:C25H20N4O3Pureza:98.44% - 99.81%Cor e Forma:SolidPeso molecular:424.45ML141
CAS:<p>ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).</p>Fórmula:C22H21N3O3SPureza:99.36% - 99.56%Cor e Forma:SolidPeso molecular:407.491A-116
CAS:<p>1A-116 is a specific Rac1 inhibitor.</p>Fórmula:C16H16F3N3Pureza:99.71%Cor e Forma:SolidPeso molecular:307.31
