Canal de Potássio
Os canais de potássio são um grupo diversificado de proteínas de membrana que facilitam o fluxo de íons de potássio (K+) através da membrana celular. Esses canais desempenham um papel crucial na manutenção do potencial de membrana em repouso, na regulação do volume celular e no controle da excitabilidade de neurônios e células musculares. Os canais de potássio estão envolvidos em vários processos fisiológicos, incluindo a regulação do ritmo cardíaco, a secreção de insulina e a liberação de neurotransmissores. A desregulação dos canais de potássio está associada a condições como arritmias, epilepsia e hipertensão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de canais de potássio para apoiar sua pesquisa em eletrofisiologia, saúde cardiovascular e neurobiologia.
Foram encontrados 277 produtos de "Canal de Potássio"
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Clofilium tosylate
CAS:<p>Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.</p>Fórmula:C28H44ClNO3SPureza:99.68%Cor e Forma:SolidPeso molecular:510.17Doxapram hydrochloride hydrate
CAS:<p>Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.</p>Fórmula:C24H33ClN2O3C24H30N2O2·ClH·H2OPureza:99.64% - >99.99%Cor e Forma:SolidPeso molecular:432.99VU6036720
<p>VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit</p>Fórmula:C20H22ClFN4O2SPureza:98.1%Cor e Forma:SoildPeso molecular:436.93Mefloquine
CAS:<p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>Fórmula:C17H16F6N2OPureza:99.89%Cor e Forma:SolidPeso molecular:378.31Glipizide
CAS:<p>Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.</p>Fórmula:C21H27N5O4SPureza:99.67% - 99.75%Cor e Forma:SolidPeso molecular:445.54NS13001
CAS:<p>NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).</p>Fórmula:C17H16ClN7Pureza:99.55%Cor e Forma:SolidPeso molecular:353.81Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Fórmula:C17H17ClF6N2OPureza:99% - 99.99%Cor e Forma:Off-White To Yellow SolidPeso molecular:414.77Dronedarone hydrochloride
CAS:<p>Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.</p>Fórmula:C31H44N2O5S·HClPureza:99.61%Cor e Forma:SolidPeso molecular:593.224-Aminopyridine
CAS:<p>4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.</p>Fórmula:C5H6N2Pureza:91.61%Cor e Forma:SolidPeso molecular:94.11Ifenprodil Tartrate
CAS:<p>Ifenprodil is a selective NMDA receptor (glutamate) antagonist.</p>Fórmula:C21H27NO2C4H6O6Pureza:99.02% - 99.55%Cor e Forma:SolidPeso molecular:400.49IK1 inhibitor PA-6
CAS:<p>IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse</p>Fórmula:C31H32N4O2Pureza:98.9%Cor e Forma:SolidPeso molecular:492.61Eleclazine hydrochloride
CAS:<p>Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).</p>Fórmula:C21H17ClF3N3O3Pureza:99.86%Cor e Forma:SolidPeso molecular:451.83Hydroxyhexamide
CAS:<p>Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.</p>Fórmula:C15H22N2O4SPureza:98.91%Cor e Forma:SolidPeso molecular:326.41Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Fórmula:C22H22FN3O3Pureza:99.19% - 99.73%Cor e Forma:SolidPeso molecular:395.43Ropivacaine
CAS:Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Fórmula:C17H26N2OPureza:97.75% - >99.99%Cor e Forma:SolidPeso molecular:274.40VU0134992 hydrochloride
CAS:VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).Fórmula:C20H32BrClN2O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:447.84Miconazole
CAS:<p>Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.</p>Fórmula:C18H14Cl4N2OPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:416.13BMS-394136
CAS:<p>BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.</p>Fórmula:C24H21Cl2FN4OPureza:98.19% - 98.67%Cor e Forma:SolidPeso molecular:471.35Terfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Fórmula:C32H41NO2Pureza:98.76% - 99.75%Cor e Forma:SolidPeso molecular:471.67Linoleoyl glycine
CAS:<p>Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.</p>Fórmula:C20H35NO3Pureza:98.96%Cor e Forma:SolidPeso molecular:337.5
