Bomba de prótons
As bombas de prótons são proteínas de membrana que transportam ativamente prótons (H+) através da membrana celular ou das membranas de organelas, criando um gradiente de prótons essencial para diversos processos celulares. A bomba de prótons mais conhecida é a H+/K+ ATPase, encontrada no revestimento do estômago, responsável pela secreção de ácido. As bombas de prótons também são cruciais na respiração celular e na regulação do pH. A desregulação da atividade das bombas de prótons está associada a condições como refluxo ácido, úlceras e acidose metabólica. Na CymitQuimica, oferecemos uma seleção de inibidores e moduladores de bombas de prótons para apoiar sua pesquisa em gastroenterologia, metabolismo e bioenergética celular.
Foram encontrados 39 produtos de "Bomba de prótons"
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Omeprazole sulfide
CAS:<p>Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.</p>Fórmula:C17H19N3O2SPureza:98.83%Cor e Forma:White To Slightly Collored Solid Solid CrystallinePeso molecular:329.42EN6
CAS:<p>EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.</p>Fórmula:C19H14F2N4O2Pureza:95.74% - 97.04%Cor e Forma:SolidPeso molecular:368.34Lansoprazole
CAS:<p>Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON</p>Fórmula:C16H14F3N3O2SPureza:99.18% - 99.84%Cor e Forma:White Crystalline PowderPeso molecular:369.36Zinc pyrithione
CAS:<p>Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.</p>Fórmula:C10H8N2O2S2ZnPureza:99.09% - 99.47%Cor e Forma:Off-White To Tan PowderPeso molecular:317.71Omeprazole
CAS:<p>Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.</p>Fórmula:C17H19N3O3SPureza:98.43% - 98.48%Cor e Forma:White SolidPeso molecular:345.42Corza6
<p>Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).</p>Fórmula:C203H293N55O61S7Cor e Forma:SolidPeso molecular:4704.29Pantoprazole Sodium Hydrate
CAS:<p>Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus</p>Fórmula:C16H14F2N3NaO4SH2OPureza:98.32%Cor e Forma:SolidPeso molecular:432.37Tenatoprazole
CAS:<p>Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).</p>Fórmula:C16H18N4O3SPureza:99.57%Cor e Forma:White Crystalline PowderPeso molecular:346.4Esomeprazole
CAS:<p>Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis.</p>Fórmula:C17H19N3O3SPureza:97.3%Cor e Forma:SolidPeso molecular:345.42(R)-Lansoprazole
CAS:<p>(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor</p>Fórmula:C16H14F3N3O2SPureza:98.09% - 98.99%Cor e Forma:Brown SolidPeso molecular:369.36Esomeprazole Magnesium trihydrate
CAS:<p>Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal</p>Fórmula:C34H42MgN6O9S2Pureza:98.52%Cor e Forma:Off-White PowderPeso molecular:767.17Thonzonium Bromide
CAS:<p>Thonzonium bromide: antimicrobial surfactant, similar to Farnesol, blocks proton transport, inhibits bone loss (EC50=69 μM).</p>Fórmula:C32H55BrN4OPureza:98.48% - 99.94%Cor e Forma:SolidPeso molecular:591.71Rabeprazole Sulfide
CAS:<p>Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.</p>Fórmula:C18H21N3O2SPureza:99.34% - 99.78%Cor e Forma:Off-White Crystalline PowderPeso molecular:343.44Vonoprazan
CAS:<p>Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and</p>Fórmula:C17H16FN3O2SPureza:99.87% - 99.92%Cor e Forma:SolidPeso molecular:345.39Esomeprazole Sodium
CAS:<p>Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.</p>Fórmula:C17H18N3O3S·NaPureza:98.17% - >99.99%Cor e Forma:SolidPeso molecular:367.4Tegoprazan
CAS:<p>Tegoprazan is an orally active, highly selective gastric H+/K+-ATPase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C20H19F2N3O3Pureza:98.22%Cor e Forma:SolidPeso molecular:387.38Chebulinic acid
CAS:<p>Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.</p>Fórmula:C41H32O27Pureza:98.91% - 99.71%Cor e Forma:SolidPeso molecular:956.68Ilaprazole sodium
CAS:<p>Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor.</p>Fórmula:C19H17N4NaO2SPureza:99.06%Cor e Forma:SolidPeso molecular:388.42Esomeprazole Magnesium
CAS:<p>Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.</p>Fórmula:C34H36MgN6O6S2Pureza:98.76% - 99.73%Cor e Forma:SolidPeso molecular:713.12Abscisic Acid
CAS:<p>Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism.</p>Fórmula:C15H20O4Pureza:99.52% - 99.73%Cor e Forma:White PowderPeso molecular:264.32Pantoprazole sodium
CAS:<p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>Fórmula:C16H14F2N3NaO4SPureza:96.92% - 99.81%Cor e Forma:White To Off-White SolidPeso molecular:405.35Ilaprazole
CAS:<p>Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.</p>Fórmula:C19H18N4O2SPureza:99.91%Cor e Forma:SolidPeso molecular:366.44Rabeprazole sodium
CAS:<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Fórmula:C18H20N3NaO3SPureza:98% - 99.912%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:381.42Bafilomycin A1
CAS:<p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>Fórmula:C35H58O9Pureza:95.87% - 99.36%Cor e Forma:SolidPeso molecular:622.83Vonoprazan Fumarate
CAS:<p>Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.</p>Fórmula:C21H20FN3O6SPureza:98.94%Cor e Forma:SolidPeso molecular:461.46Pantoprazole
CAS:<p>Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux</p>Fórmula:C16H15F2N3O4SPureza:99.28% - 99.63%Cor e Forma:Almost White SolidPeso molecular:383.37KM 91104
CAS:<p>KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.</p>Fórmula:C14H12N2O4Pureza:99.04%Cor e Forma:SolidPeso molecular:272.26Diphyllin
CAS:<p>Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.</p>Fórmula:C21H16O7Pureza:99.76% - 99.98%Cor e Forma:SolidPeso molecular:380.35ATP4A Protein, Human, Recombinant (His & Myc)
<p>ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:54.6 kDa (predicted)Omeprazole Sodium
CAS:<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Fórmula:C17H18N3NaO3SPureza:99.84%Cor e Forma:Clear In WaterPeso molecular:367.4WY-47766
CAS:<p>WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.</p>Fórmula:C14H13N3O2SPureza:97.63% - 99.83%Cor e Forma:SolidPeso molecular:287.34Saviprazole
CAS:<p>Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.</p>Fórmula:C15H10F7N3O2S2Pureza:97.07% - 97.17%Cor e Forma:SolidPeso molecular:461.38Abeprazan hydrochloride
CAS:<p>Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase</p>Fórmula:C19H18ClF3N2O3SPureza:98.57%Cor e Forma:SolidPeso molecular:446.87Ilaprazole sodium hydrate
CAS:<p>Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.</p>Fórmula:C19H21N4NaO4SPureza:99.2%Cor e Forma:SolidPeso molecular:424.45Linaprazan
CAS:<p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>Fórmula:C21H26N4O2Pureza:99.54%Cor e Forma:SolidPeso molecular:366.46Pumaprazole
CAS:<p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>Fórmula:C19H22N4O2Pureza:99.91%Cor e Forma:SolidPeso molecular:338.4Soraprazan
CAS:<p>BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that can be used to synthesize antibody-coupled active molecules.</p>Fórmula:C21H25N3O3Pureza:97.69% - 99.84%Cor e Forma:SolidPeso molecular:367.44V-ATPase-IN-1
CAS:<p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>Fórmula:C21H20ClNO2Cor e Forma:SolidPeso molecular:353.84Zastaprazan
CAS:<p>Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.</p>Fórmula:C22H26N4OPureza:99.97%Cor e Forma:SolidPeso molecular:362.48
