Bomba de prótons
As bombas de prótons são proteínas de membrana que transportam ativamente prótons (H+) através da membrana celular ou das membranas de organelas, criando um gradiente de prótons essencial para diversos processos celulares. A bomba de prótons mais conhecida é a H+/K+ ATPase, encontrada no revestimento do estômago, responsável pela secreção de ácido. As bombas de prótons também são cruciais na respiração celular e na regulação do pH. A desregulação da atividade das bombas de prótons está associada a condições como refluxo ácido, úlceras e acidose metabólica. Na CymitQuimica, oferecemos uma seleção de inibidores e moduladores de bombas de prótons para apoiar sua pesquisa em gastroenterologia, metabolismo e bioenergética celular.
Foram encontrados 42 produtos de "Bomba de prótons"
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Pantoprazole sodium
CAS:<p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>Fórmula:C16H14F2N3NaO4SPureza:96.92% - 99.81%Cor e Forma:White To Off-White SolidPeso molecular:405.35Ilaprazole
CAS:<p>Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.</p>Fórmula:C19H18N4O2SPureza:99.91%Cor e Forma:SolidPeso molecular:366.44Tenatoprazole
CAS:Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).Fórmula:C16H18N4O3SPureza:99.57%Cor e Forma:White Crystalline PowderPeso molecular:346.4Esomeprazole
CAS:Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis.Fórmula:C17H19N3O3SPureza:97.3%Cor e Forma:SolidPeso molecular:345.42Rabeprazole sodium
CAS:<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Fórmula:C18H20N3NaO3SPureza:98% - 99.912%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:381.42Bafilomycin A1
CAS:<p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>Fórmula:C35H58O9Pureza:95.87% - 99.36%Cor e Forma:SolidPeso molecular:622.83Vonoprazan Fumarate
CAS:<p>Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.</p>Fórmula:C21H20FN3O6SPureza:98.94%Cor e Forma:SolidPeso molecular:461.46Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFórmula:C16H15F2N3O4SPureza:97.16% - 99.63%Cor e Forma:Almost White SolidPeso molecular:383.37KM 91104
CAS:KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.Fórmula:C14H12N2O4Pureza:99.04%Cor e Forma:SolidPeso molecular:272.26Diphyllin
CAS:<p>Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.</p>Fórmula:C21H16O7Pureza:99.76% - 99.98%Cor e Forma:SolidPeso molecular:380.35ATP4A Protein, Human, Recombinant (His & Myc)
<p>ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:54.6 kDa (predicted)Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Fórmula:C17H18N3NaO3SPureza:99.84%Cor e Forma:Clear In WaterPeso molecular:367.4WY-47766
CAS:<p>WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.</p>Fórmula:C14H13N3O2SPureza:97.63% - 99.83%Cor e Forma:SolidPeso molecular:287.34Saviprazole
CAS:<p>Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.</p>Fórmula:C15H10F7N3O2S2Pureza:97.07% - 97.17%Cor e Forma:SolidPeso molecular:461.38Abeprazan hydrochloride
CAS:Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPaseFórmula:C19H18ClF3N2O3SPureza:98.57%Cor e Forma:SolidPeso molecular:446.87Ilaprazole sodium hydrate
CAS:Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.Fórmula:C19H21N4NaO4SPureza:99.2%Cor e Forma:SolidPeso molecular:424.45Linaprazan
CAS:<p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>Fórmula:C21H26N4O2Pureza:99.54%Cor e Forma:SolidPeso molecular:366.46Pumaprazole
CAS:<p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>Fórmula:C19H22N4O2Pureza:99.91%Cor e Forma:SolidPeso molecular:338.4Soraprazan
CAS:BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that can be used to synthesize antibody-coupled active molecules.Fórmula:C21H25N3O3Pureza:97.69% - 99.84%Cor e Forma:SolidPeso molecular:367.44(R)-(+)-Pantoprazole sodium
CAS:(R)-(+)-Pantoprazole ((R)-(+)-BY1023) sodium is a proton pump inhibitor used in the study of esophageal erosion and ulcers.Fórmula:C16H15F2N3NaO4SPeso molecular:406.36
