Transportador de monoamina
Os transportadores de monoaminas são um grupo de proteínas de membrana responsáveis pela recaptação de monoaminas—como serotonina, dopamina e norepinefrina—da fenda sináptica de volta para os neurônios pré-sinápticos. Este processo é crucial para regular os níveis de neurotransmissores e manter uma neurotransmissão adequada. A desregulação dos transportadores de monoaminas está associada a vários distúrbios psiquiátricos e neurológicos, incluindo depressão, ansiedade e doença de Parkinson. Na CymitQuimica, oferecemos uma gama de moduladores de transportadores de monoaminas para apoiar sua pesquisa em neurobiologia, saúde mental e farmacologia.
Foram encontrados 30 produtos de "Transportador de monoamina"
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Tetrabenazine
CAS:Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders.Fórmula:C19H27NO3Pureza:98% - 99.91%Cor e Forma:White To Off-White White To Off-White SolidPeso molecular:317.42Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Fórmula:C33H40N2O9Pureza:98.85% - 99.99%Cor e Forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecular:608.68FFN 511
CAS:Fluorescent false neurotransmitter (FFN)Fórmula:C17H20N2O2Pureza:98%Cor e Forma:SolidPeso molecular:284.35FFN 206 dihydrochloride
CAS:<p>FFN 206 dihydrochloride: fluorescent VMAT2 marker, detects subcellular sites, non-inhibitory to DAT.</p>Fórmula:C12H15ClN2O2Pureza:98.96% - >99.99%Cor e Forma:SolidPeso molecular:254.71VMAT2-IN-3
VMAT2-IN-3 (compound 10) is a potent inhibitor of vesicular monoamine transporter 2 (VMAT2), with a Ki value of 0.71 nM, showing promise for research in neurological or psychiatric disorders.Fórmula:C22H35NO4Peso molecular:377.25661GZ-793A
CAS:GZ-793A suppresses dopamine uptake at the vesicular monoamine transporter-2 (VMAT2. A lobelane analog, GZ-793A interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine.Fórmula:C26H38ClNO4Peso molecular:464.043,4-Dihydroxypyrovalerone HCl
CAS:3,4-Dihydroxypyrovalerone HCl is an analog of Pyrovalerone. Pyrovalerone inhibits the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET).Fórmula:C15H22ClNO3Cor e Forma:SolidPeso molecular:299.79LY-368975 hydrochloride
CAS:<p>LY-368975 hydrochloride is a bioactive chemical.</p>Fórmula:C17H22ClNOSCor e Forma:SolidPeso molecular:323.88Tetrabenazine-d6
CAS:Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.Fórmula:C19H27NO3Pureza:98%Cor e Forma:SolidPeso molecular:323.46NBI-98782
CAS:NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM)Fórmula:C19H29NO3Pureza:99.29%Cor e Forma:SolidPeso molecular:319.44Tetrabenazine Racemate
CAS:Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).Fórmula:C19H27NO3Pureza:98.65% - 98.86%Cor e Forma:SolidPeso molecular:317.42Tetrabenazine methanesulfonate
CAS:Tetrabenazine methanesulfonate: ex-antipsychotic/therapy for movement disorders, blocks neurotransmitter uptake, labels vesicle transport.Fórmula:C20H31NO6SPureza:98%Cor e Forma:SolidPeso molecular:413.53Netarsudil free base
CAS:Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Fórmula:C28H27N3O3Cor e Forma:SolidPeso molecular:453.53Valbenazine
CAS:Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.Fórmula:C24H38N2O4Pureza:97.58%Cor e Forma:SolidPeso molecular:418.57Nisoxetine
CAS:Nisoxetine is a selective NET (noradrenaline transporter) inhibitor (Kd=0.76 nM) capable of blocking voltage-gated sodium channels.Fórmula:C17H21NO2Pureza:98.71%Cor e Forma:SolidPeso molecular:271.35Decynium 22
CAS:Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitorFórmula:C23H23IN2Pureza:99.92%Cor e Forma:Dark Red CrystalsPeso molecular:454.35FFN 511 hydrochloride
CAS:FFN 511 hydrochloride is a fluorescent pseudo-neurotransmitter (FFNs) targeting VMA T2 that can be used to label baraminergic nerve endings.Fórmula:C17H21ClN2O2Pureza:99.83%Cor e Forma:SoildPeso molecular:320.81Talopram hydrochloride
CAS:noradrenalin transporter (NET) inhibitorFórmula:C20H26ClNOPureza:98%Cor e Forma:SolidPeso molecular:331.88Indatraline
CAS:Indatraline is a nonselective monoamine transporter inhibitor.Fórmula:C16H15Cl2NCor e Forma:SolidPeso molecular:292.2FFN200 dihydrochloride
CAS:FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.Fórmula:C11H14Cl2N2O2Cor e Forma:SolidPeso molecular:277.15Nisoxetine hydrochloride
CAS:Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitorFórmula:C17H21NO2·HClPureza:99.21%Cor e Forma:White SolidPeso molecular:307.82GZ-11608
CAS:GZ-11608, a selective and potent inhibitor of vesicular monoamine transporter-2 (VMAT2), presents a high affinity with a Ki value of 25 nM. It effectively reduces dopamine release induced by methamphetamine from isolated synaptic vesicles in brain dopaminergic neurons. GZ-11608 also demonstrates rapid penetration into the brain without exhibiting neurotoxicity, making it a valuable compound for researching methamphetamine use disorder [1].Fórmula:C19H25NOPeso molecular:283.41VMAT2-IN-I HCl
CAS:VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.Fórmula:C25H32ClF4NO4Pureza:98%Cor e Forma:SolidPeso molecular:521.97Imipramine pamoate
CAS:Imipramine pamoate, a potent antidepressant [1] [2], is a chemical compound widely recognized for its efficacy in treating depressive disorders.Fórmula:C61H64N4O6Cor e Forma:SolidPeso molecular:949.18(2S,3S,11bR)-Dihydrotetrabenazine
CAS:(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.Fórmula:C19H29NO3Cor e Forma:SolidPeso molecular:319.44Lafadofensine (D-(-)-Mandelic acid)
Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.Fórmula:C32H32F2N2O6Cor e Forma:SolidPeso molecular:578.6Valbenazine tosylate
CAS:Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying noFórmula:C38H54N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:762.973-Bromoamphetamine hydrochloride
CAS:3-Bromoamphetamine hydrochloride is a para-substituted amphetamine that functions as a monoamine releaser.Fórmula:C9H13BrClNCor e Forma:SolidPeso molecular:250.563(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFórmula:C19H27NO3Pureza:98.69%Cor e Forma:SolidPeso molecular:317.42VMAT2-IN-2 tosylate
CAS:<p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>Fórmula:C27H36F3NO6SPureza:98%Cor e Forma:SolidPeso molecular:559.64Ref: TM-T79061
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