Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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UK51656
CAS:UK51656 is an antagonist of calcium (IC50: 4 nM).Fórmula:C22H28ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:465.93Palonidipine
CAS:Palonidipine is an antagonist of calcium, is potential for the therapy of angina-pectoris and hypertension.Fórmula:C29H34FN3O6Pureza:98%Cor e Forma:SolidPeso molecular:539.6JTV-519 free base
CAS:JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmicFórmula:C25H32N2O2SPureza:98%Cor e Forma:SolidPeso molecular:424.6SQ-31765
CAS:SQ-31765 is a blocker of benzazepine calcium channel.Fórmula:C24H27F3N2O4Pureza:98%Cor e Forma:SolidPeso molecular:464.48TTA-A8
CAS:TTA-A8 is an antagonist of T-type calcium channel.Fórmula:C22H21F3N4O2Pureza:99.22%Cor e Forma:SolidPeso molecular:430.42Norverapamil
CAS:Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .Fórmula:C26H36N2O4Pureza:98%Cor e Forma:SolidPeso molecular:440.58Gallopamil hydrochloride
CAS:Gallopamil hydrochloride (Methoxyverapamil hydrochloride) is an antagonist of phenylalkylamine calcium.Fórmula:C28H41ClN2O5Pureza:99.86%Cor e Forma:SolidPeso molecular:521.09Ref: TM-T11353L
1mg38,00€5mg73,00€10mg90,00€25mg140,00€50mg183,00€100mg283,00€500mg692,00€1mL*10mM (DMSO)90,00€JTV-519 fumarate
CAS:Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo.Fórmula:C29H36N2O6SCor e Forma:SolidPeso molecular:540.67(2R/S)-6-PNG
CAS:(2R/S)-6-PNG (6-Prenylnaringenin) from hops is a natural histone deacetylase inhibitor that blocks T-type calcium channels reducing neurogenicity in mice.Fórmula:C20H20O5Pureza:98%Cor e Forma:SolidPeso molecular:340.37McN5691
CAS:McN5691 is a voltage sensitive calcium channel blocker.Fórmula:C30H35NO3Pureza:98.93% - 99.38%Cor e Forma:SolidPeso molecular:457.6Cyclic ADP-ribose
CAS:cADPR, made from NAD+, boosts calcium in cells via Ryanodine receptors and TRPM2 channels.Fórmula:C15H21N5O13P2Pureza:98%Cor e Forma:Lyophilized PowderPeso molecular:541.3Ned-K
CAS:Ned-K blocks NAADP, reduces heart ischemia-reperfusion calcium waves.Fórmula:C31H31N5O3Cor e Forma:SolidPeso molecular:521.61Nemadipine-A
CAS:Nemadipine A blocks L-type Ca2+ channels, alters C. elegans morphology, boosts TRAIL's cancer kill rate, and lowers Survivin in A549 cells.Fórmula:C19H18F5NO4Cor e Forma:SolidPeso molecular:419.34TDN345
CAS:TDN345 is a antagonist of Ca2+, for the treatment of vascular and senile dementia including Alzheimer's disease.Fórmula:C28H34F2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:468.58piCRAC-1
CAS:piCRAC-1 is a powerful inhibitor of the photoinducible Ca2+ release-activated Ca2+ (CRAC) channel.Fórmula:C17H10F6N4Cor e Forma:SolidPeso molecular:384.28Dopropidil
CAS:Dopropidil: anti-angina calcium regulator with anti-ischemic properties in animal models.Fórmula:C20H35NO2Pureza:98%Cor e Forma:SolidPeso molecular:321.5AJG-049 HCl
CAS:AJG-049 HCl is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).Fórmula:C27H31ClN2O2Cor e Forma:SolidPeso molecular:451.01PD-151307
CAS:PD-151307 is used as an N-type calcium channel blocker.Fórmula:C33H47N3O5Pureza:98%Cor e Forma:SolidPeso molecular:565.74(Rac)-MEM 1003
CAS:MEM-1003, a calcium channel blocker, is used potentially for the treatment of bipolar disorders.Fórmula:C22H25ClN2O5Cor e Forma:SolidPeso molecular:432.9RyRs activator 3
CAS:RyRs activator 3 (compound A4) serves as an insecticide highly effective against both the diamondback moths, M.Fórmula:C23H19BrCl2N6O3Pureza:98%Cor e Forma:SolidPeso molecular:578.25AMG-1
CAS:AMG-1 inhibits CRAC channels, blocks effector T cells, not regulatory ones, and reduces EAE progression.Fórmula:C18H9ClF5N3OCor e Forma:SolidPeso molecular:413.73RQ-00311651
CAS:RQ-00311651 is a novel T-type Ca2+ channel blocker. RQ-00311651 also inhibited high K-induced Ca signaling in those cells.Fórmula:C19H18F3N5O2Cor e Forma:SolidPeso molecular:405.37NPS-2143
CAS:NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.Fórmula:C24H25ClN2O2Pureza:99.56%Cor e Forma:SolidPeso molecular:408.92TMB 8 (hydrochloride)
CAS:TMB 8 blocks nAChRs (IC50: 390-480 nM), reduces Ca2+ in muscles, hinders rabbit aorta contraction at 50 μM, and inhibits PKC dose-dependently.Fórmula:C22H38ClNO5Cor e Forma:White SolidPeso molecular:431.99β-Amino Acid Imagabalin Hydrochloride
CAS:β-Amino Acid Imagabalin Hydrochloride is the voltage-dependent calcium channel ligand for the α2δ subunit.Fórmula:C9H20ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:209.71Sadopine
CAS:Sadopine is a high-affinity radioligand for DHP receptor in L-type Ca2+ channels, suitable for tissue and membrane labeling.Fórmula:C30H40F3N3O7SCor e Forma:SolidPeso molecular:643.71Lercanidipine. (R)-
CAS:(R)-Lercanidipine enantiomer: antihypertensive, blocks L-type Ca2+ channels, dilates blood vessels.Fórmula:C36H41N3O6Cor e Forma:SolidPeso molecular:611.73TTA-P2
CAS:TTA-P2: potent CNS-penetrating T-type Ca2+ channel blocker; eliminates Cav3.1 window currents.Fórmula:C21H29Cl2FN2O2Cor e Forma:SolidPeso molecular:431.37(R)-Lercanidipine hydrochloride
CAS:(R)-Lercanidipine hydrochloride is the R-enantiomer of Lercanidipine. (R)-lercanidipine hydrochloride is a blocker of calcium channel.Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:648.2Lidoflazine
CAS:Lidoflazine: antianginal, blocks HERG K+ & Ca channels, risks QT prolongation & arrhythmia.Fórmula:C30H35F2N3OPureza:98%Cor e Forma:SolidPeso molecular:491.62Semotiadil recemate fumarate
CAS:Semotiadil recemate fumarate is the recemate of Semotiadil fumarate. Semotiadil fumarate is a novel antagonist of vasoselective Ca2+ channel.Fórmula:C33H36N2O10SPureza:98%Cor e Forma:SolidPeso molecular:652.71Leconotide
CAS:Leconotide is a calcium channel blocker and antihyperalgesia agent; isolated from the venom of the cone snail, Conus catus.Fórmula:C107H179N35O36S7Cor e Forma:SolidPeso molecular:2756.23IDO1-IN-19
CAS:IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research.Fórmula:C25H22F4N2O3Cor e Forma:SolidPeso molecular:474.45PD0176078
CAS:PD0176078 () is a newly blocker of N-type Calcium channel.Fórmula:C23H30F2N2OPureza:99.72%Cor e Forma:SolidPeso molecular:388.49Ref: TM-T12385
1mg63,00€5mg111,00€10mg180,00€25mg284,00€50mg395,00€100mg543,00€200mg735,00€1mL*10mM (DMSO)138,00€Carboxyamidotriazole
CAS:Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways.Fórmula:C17H12Cl3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:424.67CXL-1020
CAS:CXL-1020, a HNO prodrug, enhances heart muscle function & relaxation, aiding in heart failure research.Fórmula:C7H9NO5S2Cor e Forma:SolidPeso molecular:251.28ML218
CAS:ML218 is an inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3).ML218 inhibits the synaptic activity of subthalamic nucleus (STN) neurons.Fórmula:C19H26Cl2N2OPureza:99.2% - 99.45%Cor e Forma:SolidPeso molecular:369.33Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Fórmula:C16H17BrClN3O3·HBrPureza:97.01% - 99.73%Cor e Forma:SolidPeso molecular:495.59Ref: TM-T3524
1mg37,00€2mg52,00€5mg79,00€10mg112,00€25mg219,00€50mg328,00€100mg495,00€500mg947,00€1mL*10mM (DMSO)88,00€18:0 LYSO-PE
CAS:18:0 LYSO-PE is a compound that induces an increase in [Ca2+]i and can be used as a phospholipid (PL) standard for lipid analysis by electrospray mass spectrometry (ESI-MS)/MS.Fórmula:C23H48NO7PPureza:98%Cor e Forma:SolidPeso molecular:481.6DHP-218
CAS:DHP-218, a calcium channel blocker, inhibits rat aorta contractions; pA2: 9.11, IC50: 6.3 nmol/L (high K+) & 66 nmol/L (phenylephrine).Fórmula:C18H21N2O7PPureza:98%Cor e Forma:SolidPeso molecular:408.34AH-1058 HCl
CAS:AH-1058 HCl is a lipophilic antiarrhythmic calcium channel blocker.Fórmula:C30H29ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:501.02O-1602
CAS:O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatmentFórmula:C17H22O2Pureza:99.85%Cor e Forma:SolidPeso molecular:258.36Ref: TM-T23097
1mg47,00€5mg90,00€10mg144,00€25mg268,00€50mg378,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)100,00€CP-060
CAS:CP-060 is a potent Ca2+ antagonist and inhibits Ca2+ overload with antioxidant and cardioprotective activities.Fórmula:C30H42N2O5SPureza:99.54%Cor e Forma:SolidPeso molecular:542.73Ref: TM-T10874
1mg239,00€5mg474,00€10mg638,00€25mg950,00€50mg1.283,00€100mg1.730,00€200mg2.337,00€1mL*10mM (DMSO)642,00€PD173212
CAS:PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2).Fórmula:C38H53N3O3Pureza:99.84%Cor e Forma:SolidPeso molecular:599.85Ref: TM-T16448
2mg46,00€5mg80,00€10mg116,00€25mg190,00€50mg284,00€100mg395,00€200mg560,00€1mL*10mM (DMSO)96,00€Cronidipine
CAS:Cronidipine (LF 20254), a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.Fórmula:C30H32ClN3O8Pureza:99.47%Cor e Forma:SolidPeso molecular:598.04Enecadin
CAS:Enecadin is a neuroprotective agent.Fórmula:C21H28FN3OPureza:98.53%Cor e Forma:SolidPeso molecular:357.46Fenoverine
CAS:Fenoverine (Spasmopriv) has antispasmodic activity and can be used to study gastrointestinal spasms.Fórmula:C26H25N3O3SPureza:98.34%Cor e Forma:SolidPeso molecular:459.56Ref: TM-T62889
1mg70,00€5mg150,00€10mg235,00€25mg472,00€50mg755,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)154,00€Ticolubant
CAS:Ticolubant: Oral LTB4 antagonist, Ki=0.78 nM; blocks Ca2+ migration, IC50=6.6 nM; anti-inflammatory in mice.Fórmula:C23H19Cl2NO3SPureza:99.5%Cor e Forma:SolidPeso molecular:460.37N106
CAS:N106 is an activator of the SUMO-activating enzyme, E1 ligase, and triggers intrinsic sumoylation of SERCA2a. N106 can be used in studies about heart failure.Fórmula:C17H14N4O3SPureza:99.69%Cor e Forma:SolidPeso molecular:354.38Lifarizine
CAS:Lifarizine (RS-87476), a calcium-sodium channel antagonist, shows neuroprotective activity in a simplified rat survival model of double vessel occlusion.Fórmula:C29H32N4Pureza:99.88%Cor e Forma:SolidPeso molecular:436.59CERM-11956
CAS:Pelretin (BASF 43915) is a potential protein inhibitor for the study of dermatologic diseases.Fórmula:C29H38N2O7Pureza:99.38%Cor e Forma:SolidPeso molecular:526.628-Bromo-cGMP sodium
CAS:<p>8-Bromo-cGMP sodium: PKG activator, eases pain, dilates vessels, reduces Ca2+ currents & insulin release.</p>Fórmula:C10H10BrN5NaO7PPureza:99.45%Cor e Forma:SolidPeso molecular:446.09Cerebrocrast
CAS:Cerebrocrast (IOS-11212) has anti-inflammatory and hypoglycemic activity, blocks human platelet activation, and is used in the study of diabetes.Fórmula:C26H35F2NO7Pureza:99.71%Cor e Forma:SolidPeso molecular:511.56Tiapamil hydrochloride
CAS:Tiapamil hydrochloride (Ro 11-1781 hydrochloride) is a calcium channel blocker with antihypertensive activity used in the study of angina pectoris.Fórmula:C26H38ClNO8S2Pureza:99.17%Cor e Forma:SolidPeso molecular:592.16GSK205
CAS:GSK205 is a selective TRPV4 antagonist (IC50: 4.19 μM) for inhibiting TRPV4-mediated Ca2+ influx.Fórmula:C24H25BrN4SPureza:99.46%Cor e Forma:SolidPeso molecular:481.45Ref: TM-T11480
1mg70,00€5mg154,00€10mg235,00€25mg518,00€50mg847,00€100mg1.359,00€1mL*10mM (DMSO)162,00€Crobenetine
CAS:Crobenetine (BIII 890 CL) Free Base is a selective NaV channel blocker that eliminates VTD-induced [Ca2+] elevation.Fórmula:C25H33NO2Pureza:98.99%Cor e Forma:SolidPeso molecular:379.54SAK3
CAS:SAK3 is a modulator of nAChR activity and is used to study memory deficits and Alzheimer's disease.Fórmula:C20H23N3O4Pureza:98.37% - 99.43%Cor e Forma:SolidPeso molecular:369.41R 56865
CAS:R 56865 is a weak potential-operated channel inhibitor that inhibits the late sodium current in human isolated cardiomyocytes.Fórmula:C23H28FN3OSPureza:99.52%Cor e Forma:SolidPeso molecular:413.55FPL-62129
CAS:FPL-62129 is a calcium channel antagonist and a novel angiotensin-converting enzyme inhibitor with vasodilator activity for the study of cardiovascular disease.Fórmula:C20H19ClF5NO4Pureza:98.27% - 99.34%Cor e Forma:SolidPeso molecular:467.81Opc 8490
CAS:Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator, which prolongs the atrial action potential in a concentration-dependent manner.Fórmula:C30H35N3O10Pureza:98.88%Cor e Forma:SolidPeso molecular:597.61NecroX-5
CAS:<p>NecroX-5, a derivative of NecroX, exhibits anti-inflammatory and anti-cancer activities. NecroX-5 reduces intracellular calcium concentration.</p>Fórmula:C27H39N3O9S3Pureza:99.944%Cor e Forma:SolidPeso molecular:645.81Terflavoxate
CAS:<p>Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine.</p>Fórmula:C26H29NO4Pureza:98%Cor e Forma:SolidPeso molecular:419.51AZD-1305
CAS:<p>AZD-1305: novel anti-arrhythmic blocking IKr, Ca, Na currents; useful in arrhythmia research.</p>Fórmula:C22H31FN4O4Pureza:99.31% - 99.86%Cor e Forma:SolidPeso molecular:434.5Diproteverine HCl
CAS:<p>Diproteverine HCl is a novel calcium antagonist with antianginal properties, antispasmodic and vasoactive.</p>Fórmula:C26H36ClNO4Pureza:98.55% - 99.84%Cor e Forma:SolidPeso molecular:462.02Sulcardine sulfate
CAS:<p>Sulcardine sulfate (B-87823) is a multi-ion channel blocker with antiarrhythmic activity that inhibits Na+, K+, and Ca2+ channels.</p>Fórmula:C24H35N3O8S2Pureza:98.74%Cor e Forma:SolidPeso molecular:557.68Tamolarizine
CAS:<p>Tamolarizine (Tamolarizine free base) free base is a novel calcium antagonist.</p>Fórmula:C27H32N2O3Pureza:98.17%Cor e Forma:SoildPeso molecular:432.55Clopimozide
CAS:Clopimozide (R-29764), a long-acting oral antischizophrenic, blocks calcium channels and [3H] nilandipine binding.Fórmula:C28H28ClF2N3OPureza:98.99% - 99.66%Cor e Forma:SolidPeso molecular:495.99Upacicalcet
CAS:Upacicalcet (AJT-240) is a calcium mimetic for SHPT in dialysis, reducing PTH by targeting parathyroid receptors.Fórmula:C11H14ClN3O6SPureza:99.88%Cor e Forma:SolidPeso molecular:351.76SERCA2a activator 1
CAS:SERCA2a activator 1 boosts heart function by reducing phospholamban restraint and enhancing cardiac contraction-relaxation cycles.Fórmula:C32H29N3O4SPureza:99.75%Cor e Forma:SolidPeso molecular:551.66Ref: TM-T16873
1mg187,00€5mg472,00€10mg660,00€25mg1.035,00€50mg1.483,00€100mg2.072,00€1mL*10mM (DMSO)563,00€Vatanidipine
CAS:Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lastingFórmula:C41H42N4O6Pureza:99.95%Cor e Forma:SolidPeso molecular:686.8Ref: TM-T24932
1mg187,00€5mg454,00€10mg622,00€25mg940,00€50mg1.264,00€100mg1.663,00€1mL*10mM (DMSO)730,00€Gallopamil
CAS:Gallopamil blocks acid secretion (IC50: 10.9 μM), acts as antiarrhythmic, vasodilator, and is a methoxy Verapamil derivative.Fórmula:C28H40N2O5Pureza:99.85%Cor e Forma:SolidPeso molecular:484.63Ref: TM-T11353
1mg38,00€5mg79,00€10mg119,00€25mg188,00€50mg283,00€100mg430,00€500mg938,00€1mL*10mM (DMSO)85,00€DS16570511
CAS:DS16570511 is a novel, cell-permeable inhibitor targeting the mitochondrial calcium uniporter.Fórmula:C30H25Cl2N3O4Pureza:98.34% - 98.45%Cor e Forma:SolidPeso molecular:562.44VU 0240551
CAS:VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.Fórmula:C16H14N4OS2Pureza:99.9%Cor e Forma:SolidPeso molecular:342.44Ref: TM-TQ0139
1mg37,00€5mg78,00€10mg125,00€25mg255,00€50mg439,00€100mg705,00€200mg938,00€500mg1.415,00€1mL*10mM (DMSO)86,00€Mioflazine hydrochloride
CAS:Mioflazine hydrochloride is a nucleoside transport inhibitor that acts on adenosine to improve sleep.Fórmula:C29H34Cl4F2N4O3Cor e Forma:SolidPeso molecular:666.41KCa1.1 channel activator-1
A selective vascular KCa1.1 channel stimulator with CaV1.2 blocking ability and mild myorelaxant effects.Fórmula:C25H16O10Cor e Forma:SolidPeso molecular:476.39RS 5773
CAS:RS 5773 is a benzothiazepine derivative with antianginal effects.Fórmula:C29H33ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:541.1Naltiazem
CAS:Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction.Fórmula:C26H28N2O4SPureza:98%Cor e Forma:SolidPeso molecular:464.58Darodipine
CAS:Darodipine (PY-108068) is a dihydropyridine type Ca+2 antagonist.Fórmula:C19H21N3O5Pureza:99.67%Cor e Forma:SolidPeso molecular:371.39Cavα2δ1&NET-IN-3
CAS:Cavα2δ1&NET-IN-3 (example 216) is an inhibitor targeting both the α2δ subunit of voltage-gated calcium channels (VGCC) and the noradrenaline transporter (NET).Fórmula:C24H30N6O2SCor e Forma:SolidPeso molecular:466.6A 425619
CAS:A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonistFórmula:C18H14F3N3OPureza:99.75%Cor e Forma:SolidPeso molecular:345.32Ref: TM-T8562
1mg64,00€5mg137,00€10mg215,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)144,00€Coelenterazine h
CAS:Coelenterazine H, a Ca2+ sensitive synthetic derivative, is a luminescent biomolecule used to measure Ca2+ changes.Fórmula:C26H21N3O2Pureza:99.58%Cor e Forma:Yellow To Brownish PowderPeso molecular:407.46Ref: TM-T14994
1mg87,00€5mg216,00€10mg354,00€25mg582,00€50mg825,00€100mg1.111,00€200mg1.491,00€500µg67,00€Iganidipine HCl
CAS:NKY-722 (HCl), also known as Iganidipine, is a calcium channel blocker potentially for the treatment of glaucoma.Fórmula:C28H40Cl2N4O6Cor e Forma:SolidPeso molecular:599.55Budiodarone
CAS:Budiodarone (ATI-2042) resembles amiodarone, potentially preventing atrial fibrillation.Fórmula:C27H31I2NO5Cor e Forma:SolidPeso molecular:703.35(S)-(-)-Bay-K-8644
CAS:(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.Fórmula:C16H15F3N2O4Pureza:98.28% - 99.37%Cor e Forma:SolidPeso molecular:356.3Nelutroctiv
CAS:Nelutroctiv is a potent activator of cardiac troponin.Fórmula:C24H22F5N3O4SCor e Forma:SolidPeso molecular:543.51Halofuginone hydrochloride
CAS:Halofuginone hydrochloride (RU-19110), a derivative of Febrifugine, functions as a competitive inhibitor of prolyl-tRNA synthetase, displaying a Ki value of 18.3 nM. This compound effectively inhibits type-I collagen synthesis, providing therapeutic benefits in osteoarthritis (OA) by impeding TGF-β signaling. Additionally, it serves as a potent pulmonary vasodilator, mainly through the activation of Kv channels and the inhibition of various calcium channels including voltage-gated, receptor-operated, and store-operated ones. Beyond its vascular effects, Halofuginone hydrochloride exhibits a broad spectrum of biological activities, including anti-malarial, anti-inflammatory, anti-cancer, and anti-fibrotic properties, supported by multiple studies.Fórmula:C16H18BrCl2N3O3Cor e Forma:SolidPeso molecular:451.14Piprofurol
CAS:Piprofurol is used as a Calcium channel blocker.Fórmula:C26H33NO6Pureza:98%Cor e Forma:SolidPeso molecular:455.54HA-1004 dihydrochloride
CAS:HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel proteinFórmula:C12H16ClN5O2SPureza:98%Cor e Forma:White Crystalline SolidPeso molecular:329.81Iganidipine
CAS:Iganidipine（NKY 722） is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.Fórmula:C28H38N4O6Pureza:96.3%Cor e Forma:SolidPeso molecular:526.62LOE 908 hydrochloride
CAS:Broad spectrum cation channel blockerFórmula:C41H49ClN2O9Pureza:98%Cor e Forma:SolidPeso molecular:749.29N-type calcium channel blocker-1
CAS:N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.Fórmula:C31H47N3Pureza:98%Cor e Forma:SolidPeso molecular:461.73ATI-22-107
CAS:ATI-22-107 is a positive cardiac inotropic agent which may affect myocyte calcium cycling and contractility.Fórmula:C31H32Cl2N4O8Cor e Forma:SolidPeso molecular:659.51RO 23-6152
CAS:RO 23-6152, a new calcium antagonist, can inhibit platelet aggregation in vitro associated with occlusive coronary thrombus formation.Fórmula:C26H29ClN2O4SCor e Forma:SolidPeso molecular:501.04Mioflazine
CAS:Mioflazine suppresses nucleoside uptake. Mioflazine is an orally active nucleoside transport inhibitor. It has the potential for sleep disorders treatment.Fórmula:C29H30Cl2F2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:575.485J-4
CAS:<p>5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE).</p>Fórmula:C16H12N2O3SPureza:96.12%Cor e Forma:SolidPeso molecular:312.34TROX-1
CAS:TROX-1 is the activation state-dependent Cav2 channel antagonist.Fórmula:C22H16ClFN6OPureza:98%Cor e Forma:SolidPeso molecular:434.85Cav 3.2 inhibitor 4
CAS:<p>Cav 3.2 Inhibitor 4 (Compound 21) is a selective and potent inhibitor of the T-type calcium channel (Ca v 3.2), demonstrating peripheral restriction with an</p>Fórmula:C21H32Cl2N4O3Pureza:98%Cor e Forma:SolidPeso molecular:459.41Mioflazine hydrochloride anhydrous
CAS:Mioflazine hydrochloride anhydrous is a nucleoside transport inhibitor that acts on adenosine to improve sleep.Fórmula:C29H32Cl4F2N4O2Cor e Forma:SolidPeso molecular:648.4MONIRO-1
CAS:MONIRO-1 blocks T/N-type Ca²⁺ channels: hCav2.2 (IC50: 34μM), hCav3.1 (3.3μM), hCav3.2 (1.7μM), hCav3.3 (7.2μM).Fórmula:C23H24ClFN4O3Cor e Forma:SolidPeso molecular:458.92TMDJ-035
CAS:TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2).Fórmula:C16H12F3N5OPureza:98%Cor e Forma:SolidPeso molecular:347.29BBT
CAS:BBT has anti-hyperglycemic activity, protecting beta cells from cytokine or streptozotocin-induced cell death, and restoring beta cell function.Fórmula:C18H12BrNO2SPureza:99.02%Cor e Forma:SolidPeso molecular:386.268-bromo NAD+ sodium
CAS:8-Bromo NAD+ serves as a prodrug for the cyclic ADP-ribose (cADPR) inhibitor, 8-bromo cADPR, undergoing conversion to its active form by the enzyme CD38.Fórmula:C21H25BrN7O14P2·NaCor e Forma:SolidPeso molecular:764.30Fluspirilene
CAS:Fluspirilene is a long-acting antipsychotic for schizophrenia, inhibiting L-type calcium channels (IC50: 0.03 μM).Fórmula:C29H31F2N3OPureza:99.59%Cor e Forma:SolidPeso molecular:475.57Reldesemtiv
CAS:<p>Reldesemtiv (CK-2127107) boosts exercise capacity, targeting fast muscle troponin, EC50 3.4 μM.</p>Fórmula:C19H18F2N6OPureza:97.27%Cor e Forma:SolidPeso molecular:384.38AY 77
CAS:<p>AY 77: Potent, selective PAR2 agonist, favors Ca2+ (ec50=40nM) & ERK1/2 (ec50=2μM), boosts breast cancer cell migration.</p>Fórmula:C21H32N4O4Pureza:99.7%Cor e Forma:SolidPeso molecular:404.5Bupivacaine hydrochloride monohydrate
CAS:Bupivacaine hydrochloride monohydrate is an NMDA receptor inhibitor that inhibits SCN5A channels and is commonly used in the study of chronic pain.Fórmula:C18H31ClN2O2Pureza:99.91%Cor e Forma:SolidPeso molecular:342.9Cis-22a
CAS:Cis-22a: selective TRPV6 inhibitor (IC50=0.32μM), halts T47D breast cancer cell growth.Fórmula:C24H30F3N3O2Pureza:99.99%Cor e Forma:SolidPeso molecular:449.51EMD57033
CAS:EMD57033 activates cardiac troponin C, enhances Ca2+ sensitivity to boost heart contraction.Fórmula:C22H23N3O4SPureza:97.24% - 99.11%Cor e Forma:SolidPeso molecular:425.5Calcium channel-modulator-1
CAS:<p>Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.</p>Fórmula:C26H24Cl2N2O7SPureza:99.95%Cor e Forma:SolidPeso molecular:579.45PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Fórmula:C33H33N3O4Cor e Forma:SolidPeso molecular:535.63NNC 55-0396
CAS:NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.Fórmula:C30H40Cl2FN3O2Pureza:99.00%Cor e Forma:SolidPeso molecular:564.56Ref: TM-T12238
1mg66,00€5mg126,00€10mg202,00€25mg354,00€50mg550,00€100mg787,00€1mL*10mM (DMSO)160,00€Sesamodil
CAS:<p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>Fórmula:C29H32N2O6SPureza:98.58% - 99.01%Cor e Forma:SolidPeso molecular:536.64Cav 3.2 inhibitor 1
Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.Fórmula:C32H39N3OCor e Forma:SolidPeso molecular:481.67Calpain Inhibitor-2
CAS:Calpain Inhibitor-2: Lipophilic, moderates growth of A-375, B-16F1, PC-3 cancers, and hinders 80% DU-145 cell invasion.Fórmula:C26H33N3O5SCor e Forma:SolidPeso molecular:499.62Cav 3.2 inhibitor 3
Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.Fórmula:C32H37N3O2Cor e Forma:SolidPeso molecular:495.66AZD 2066 hydrate
AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].Fórmula:C19H18ClN5O3Cor e Forma:SolidPeso molecular:386.33PD-217014
CAS:PD-217014 is an α2δ ligand that exhibits visceral analgesic activity and can suppress visceral hypersensitivity. Its antihyperalgesic effects are dose-dependent.Fórmula:C10H17NO2Cor e Forma:SolidPeso molecular:183.25SR 33805 oxalate
CAS:Ca2+ channel antagonistFórmula:C34H42N2O9SPureza:98%Cor e Forma:SolidPeso molecular:654.77IAB15
CAS:IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Fórmula:C15H14F3NO2Cor e Forma:SolidPeso molecular:297.27IAA65
CAS:IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].Fórmula:C16H13F6NO2Cor e Forma:SolidPeso molecular:365.27Cav 3.1 blocker 1
CAS:Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel inhibitor with an IC50 value of 160 nM for Cav3.1. It exhibits weaker inhibition on Cav 3.2 with an IC50 of 5000 nM and shows no inhibitory effect on Cav 3.3 and Cav 1.2 (IC50 > 10000 nM).Fórmula:C26H19F6N3O2Peso molecular:519.438Mibefradil dihydrochloride hydrate
CAS:Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Fórmula:C29H42Cl2FN3O4Cor e Forma:SolidPeso molecular:586.57Cav 2.2/3.2 blocker 1
Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM & 80 μM, respectively; penetrates CNS.Fórmula:C28H30N2O3Cor e Forma:SolidPeso molecular:442.55SB-423557
CAS:SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nMFórmula:C28H36N2O4Pureza:98%Cor e Forma:SolidPeso molecular:464.60(rel)-Mirogabalin
CAS:(rel)-Mirogabalin ((rel)-DS5565) is an inhibitor of voltage-dependent calcium channels, specifically targeting the α2δ-1 subunit.Fórmula:C12H19NO2Cor e Forma:SolidPeso molecular:209.28Mibefradil
CAS:Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).Fórmula:C29H38FN3O3Pureza:98%Cor e Forma:SolidPeso molecular:495.63Cav 3.2 inhibitor 2
Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.Fórmula:C32H37F2N3OCor e Forma:SolidPeso molecular:517.65T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Fórmula:C36H39FN4OSCor e Forma:SolidPeso molecular:594.78TTA-P1
CAS:TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Fórmula:C19H27Cl2FN2OCor e Forma:SolidPeso molecular:389.33BER-5
CAS:BER-5 is a potent MrgX2 antagonist, demonstrating broad-spectrum antagonistic activity against various MrgX2 agonists. It can inhibit Substance P(SP)-induced degranulation in LAD2 cells and alleviate SP-induced allergic reactions in mice. BER-5 is useful for researching mechanisms related to allergic reactions.Fórmula:C20H16O4Cor e Forma:SolidPeso molecular:320.34Emopamil
CAS:Emopamil, a calcium channel inhibitor, reduces neuronal damage caused by ischemia.Fórmula:C23H30N2Cor e Forma:SolidPeso molecular:334.5CAD204520
CAS:CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).Fórmula:C23H32F3N3O2Cor e Forma:SolidPeso molecular:439.51RWJ 22108
CAS:RWJ 22108 is a bronchial-selective calcium channel (calcium channel) blocker that exhibits an IC50 of 5.7 nM in dog bronchial smooth muscle calcium-dependent contractions.Fórmula:C27H30ClFN2O4SCor e Forma:SolidPeso molecular:533.06CCR4 antagonist 2
CAS:CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits TregFórmula:C26H28Cl2N6OPureza:98%Cor e Forma:SolidPeso molecular:511.45Leualacin
CAS:Leualacin is a novel calcium blocker from Hapsidospora irregularis.Fórmula:C31H47N3O7Pureza:98%Cor e Forma:SolidPeso molecular:573.72MP-010
CAS:<p>MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.</p>Fórmula:C14H20N4O2SCor e Forma:SolidPeso molecular:308.399Verapamil EP Impurity C hydrochloride
CAS:NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.Fórmula:C12H20ClNO2Cor e Forma:SolidPeso molecular:245.75(Rac)-PD0299685
CAS:<p>(Rac)-PD0299685 is a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.</p>Fórmula:C10H21NO2Pureza:97.20%Cor e Forma:SolidPeso molecular:187.28Fostedil
CAS:Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.Fórmula:C18H20NO3PSPureza:98%Cor e Forma:SolidPeso molecular:361.4
