Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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Ionomycin calcium
CAS:<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Fórmula:C41H70CaO9Pureza:98% - 98.11%Cor e Forma:SolidPeso molecular:747.07ORM-10103
CAS:ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).ORM-10103 inhibited NCX currents with estimated IC50 values of 55 and 67 nMFórmula:C20H16N2O4Pureza:99.9%Cor e Forma:SolidPeso molecular:348.35Ref: TM-T12321
1mg43,00€5mg90,00€10mg135,00€25mg278,00€50mg445,00€100mg605,00€200mg817,00€1mL*10mM (DMSO)90,00€R-(-)-Niguldipine hydrochloride
CAS:R-(-)-Niguldipine HCl: L-type Ca2+ blocker, K+ agonist, α1A antagonist; lowers blood pressure; weaker enantiomer.Fórmula:C36H40ClN3O6Cor e Forma:SolidPeso molecular:646.17Falipamil
CAS:Produto Controlado<p>Applications Falipamil is a specific bradycardic agent and a calcium channel blocker.<br>References Boucher, M., et al.: Eur. J. Pharmacol., 306, 93 (1996), Mubagwa, K., et al.: Arch. Int. Pharmacodyn. Ther., 286, 71 (1987), Chaudhry, A., et al.: Development Cardiovascular Medicine, 46, 196 (1985), Ogiwara, Y., et al.: Jpn Heart J., 29, (1988)<br></p>Fórmula:C24H32N2O5Cor e Forma:NeatPeso molecular:428.52(S)-Lercanidipine Hydrochloride
CAS:Produto ControladoFórmula:C36H41N3O6·ClHCor e Forma:NeatPeso molecular:648.19Dihydrocinnamyl Cilnidipine
Produto Controlado<p>Applications Dihydrocinnamyl Cilnidipine is a metabolite of Cilnidipine (C441375); a dihydropyridine calcium channel blocker.<br>References Ikeda, K., et al.: Oyo Yakuri, 44, 433 (1992); Hosono, M., et al.: J. Pharmacobio-Dyn., 15, 547, (1992); Ishii, M.: Japan Pharmacol. Ther., 21, 59 (1993)<br></p>Fórmula:C27H30N2O7Cor e Forma:NeatPeso molecular:494.543-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine
Produto Controlado<p>Stability Light and Temperature Sensitive<br>Applications 3-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine is a derivative of Amlodipine (A633495); a dihydropyridine calcium channel blocker where activity mainly resides in the (-)-isomer.<br>References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995)<br></p>Fórmula:C36H30ClN3O9Cor e Forma:NeatPeso molecular:684.091(R)-Lercanidipine Hydrochloride
CAS:Produto ControladoFórmula:C36H41N3O6·ClHCor e Forma:NeatPeso molecular:648.19Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Fórmula:C16H17BrClN3O3Pureza:99.53%Cor e Forma:Off-White SolidPeso molecular:414.68Ref: TM-T6856
1mg37,00€5mg87,00€10mg123,00€25mg240,00€50mg363,00€100mg547,00€500mg1.198,00€1mL*10mM (DMSO)A consultarVerapamil
CAS:Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, and angina research.Fórmula:C27H38N2O4Pureza:99.61% - 99.93%Cor e Forma:OilPeso molecular:454.6Ref: TM-T20656
10mg35,00€25mg51,00€50mg73,00€100mg96,00€200mg143,00€500mg230,00€1mL*10mM (DMSO)55,00€Aladorian
CAS:Aladorian (ARM036), a benzothiazepine, has anti-arrhythmic properties for heart failure and CPVT research.Fórmula:C12H13NO4SPureza:98%Cor e Forma:SolidPeso molecular:267.3Aprindine hydrochloride
CAS:Aprindine HCl, a Class 1b antiarrhythmic, treats heart arrhythmias, outperforming digoxin in delaying atrial fibrillation. It's effective orally.Fórmula:C22H31ClN2Cor e Forma:SolidPeso molecular:358.95Levamlodipine gentisate
CAS:Levamlodipine gentisate, an active amlodipine enantiomer, is a dihydropyridine calcium channel blocker for treating hypertension and angina.Fórmula:C27H31ClN2O9Pureza:98%Cor e Forma:SolidPeso molecular:563Ethacrynate Sodium
CAS:Ethacrynate Sodium, a sodium salt, blocks chloride, potassium, and sodium transport mainly in Henle's loop.Fórmula:C13H12Cl2NaO4Pureza:98%Cor e Forma:SolidPeso molecular:326.12JTV-519 hemifumarate
CAS:JTV-519 hemifumarate: Ca2+ blocker, SERCA inhibitor, ryanodine receptor partial agonist; antiarrhythmic, cardioprotective.Fórmula:C54H68N4O8S2Pureza:98%Cor e Forma:SolidPeso molecular:965.28JTV-519
CAS:K201 (JTV-519) is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) byFórmula:C25H33ClN2O2SPureza:99.88%Cor e Forma:SolidPeso molecular:461.06Ref: TM-T24239
1mg60,00€5mg110,00€10mg155,00€25mg248,00€50mg365,00€100mg545,00€500mg1.188,00€1mL*10mM (DMSO)134,00€S-312-d
CAS:S-312d is a calcium channel antagonist. S-312-d can offer marked neuronal protective effects against ischemic injury.Fórmula:C20H22N2O4SPureza:98%Cor e Forma:SolidPeso molecular:386.46UK-52831
CAS:UK-52831, a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.Fórmula:C22H26Cl2N6O5Pureza:98%Cor e Forma:SolidPeso molecular:525.39Niguldipine Free Base
CAS:<p>Niguldipine Free Base is a calcium channel blocker and a₁-adrenergic receptor antagonist and a clinical modulator of multidrug resistance.</p>Fórmula:C36H39N3O6Pureza:98.97%Cor e Forma:SolidPeso molecular:609.71CGP 28392
CAS:CGP 28392 is used as a partial calcium channel agonist.Fórmula:C18H17F2NO5Pureza:98%Cor e Forma:SolidPeso molecular:365.33Kadethrin
CAS:Kadethrin is a synthetic pyrethroid. It was used as a pesticide.Fórmula:C23H24O4SPureza:98%Cor e Forma:Yellow-Brown Viscous Oil SolidPeso molecular:396.5N-Salicyloyltryptamine
CAS:N-Salicyloyltryptamine (STP): a tryptamine with anticonvulsant, anti-inflammatory, analgesic effects; inhibits Na+, Ca2+, K+ channels (IC50 34.6 μM).Fórmula:C17H16N2O2Cor e Forma:SolidPeso molecular:280.32YS-035 hydrochloride
CAS:inhibitor of outward K+ currentsFórmula:C21H30ClNO4Pureza:98%Cor e Forma:SolidPeso molecular:395.92Norbormide
CAS:Norbormide is a toxic compound used as a rodenticide. It has several mechanisms of action, acting as a vasoconstrictor and calcium channel blocker.Fórmula:C33H25N3O3Pureza:98%Cor e Forma:Crystals From Methylene Chloride + Ether Norbormide Is A Colorless To Off-White Crystalline Powder Used As A Selective Rat Poison (Epa 1998)Peso molecular:511.57Anipamil
CAS:Anipamil is a long-acting blocker of calcium channel,and for the treatment of cardiovascular disease.Fórmula:C34H52N2O2Pureza:98%Cor e Forma:SolidPeso molecular:520.79(S)-Lercanidipine hydrochloride
CAS:(S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-lercanidipine hydrochloride is a potent blocker of calcium channel.Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:648.19SOCE inhibitor 1
CAS:SOCE inhibitor 1 is a inhibitor of store-operated calcium entry (SOCE)(IC50 of 4.4 μM).Fórmula:C25H22F3N5O4Pureza:98%Cor e Forma:SolidPeso molecular:513.47GSK-5498A
CAS:GSK-5498A: Selective CARC blocker, inhibits release of mediators from mast cells and cytokines from T-cells (IC50, 1 μM).Fórmula:C18H11F6N3OCor e Forma:SolidPeso molecular:399.29Lemildipine
CAS:Lemildipine is a new blocker of dihydropyridine calcium entry.Fórmula:C20H22Cl2N2O6Cor e Forma:SolidPeso molecular:457.3GSK-5503A
CAS:GSK-5503A is a novel channel blocker of CRAC.Fórmula:C23H17F2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:405.4ORM-10962
CAS:ORM-10962 is a potent, highly selective inhibitor of sodium-calcium exchanger (NCX) (for the reverse and forward mode inhibition with IC50 values of 67 and 55Fórmula:C27H29N3O4Pureza:98%Cor e Forma:SolidPeso molecular:459.54PD-217014 HCl
CAS:PD-217014, a GABA analog, blocks (3)H-gabapentin on alpha(2)delta calcium channels (K(i) 18 nmol/l), and is a visceral analgesic.Fórmula:C11H19NO2Pureza:98%Cor e Forma:SolidPeso molecular:197.27A 39355
CAS:A 39355 may specifically overcome multidrug resistance without the serious hypotensive effects associated with calcium antagonists.Fórmula:C28H39Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:504.54NP-252
CAS:NP-252 is a calcium channel antagonist potentially for the treatment of angina pectoris and congestive heart failure.Fórmula:C26H35N3O5Pureza:98%Cor e Forma:SolidPeso molecular:469.57KB-130015
CAS:KB-130015, a activator of hERG1 potassium channels, blocks native and recombinant hERG1 channels at high voltages.Fórmula:C18H14I2O4Pureza:98%Cor e Forma:SolidPeso molecular:548.11Watanidipine dihydrochloride
CAS:Watanidipine dihydrochloride is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.Fórmula:C41H44Cl2N4O6Pureza:98%Cor e Forma:SolidPeso molecular:759.73Gallopamil, (-)-
CAS:Gallopamil, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms.Fórmula:C28H40N2O5Pureza:98%Cor e Forma:SolidPeso molecular:484.63AK-2-38
CAS:AK-2-38 is a nifedipine analogue with potent smooth muscle calcium antagonist action and partial agonist effects on isolated guinea pig left atrium.Fórmula:C26H30N2O4Pureza:98%Cor e Forma:SolidPeso molecular:434.53Falipamil
CAS:Falipamil, a verapamil derivative, is a calcium channel blocker with antitachycardic and potential antianginal effects.Fórmula:C24H32N2O5Pureza:98%Cor e Forma:SolidPeso molecular:428.52Tiropramide
CAS:Tiropramide is an antispasmodic drug. It also useful to inhibit the contractile response of the urinary bladder and in managing abdominal pain in IBS.Fórmula:C28H41N3O3Pureza:98%Cor e Forma:SolidPeso molecular:467.64Bms 188107
CAS:Bms 188107 is a calcium antagonist, it has cardioprotective effects.Fórmula:C25H26N2O4Pureza:98%Cor e Forma:SolidPeso molecular:418.48AZD 2066
CAS:AZD 2066 is a selective, orally active, and brain-penetrant mGluR5 antagonist with analgesic activity.Fórmula:C19H16ClN5O2Pureza:98%Cor e Forma:SolidPeso molecular:381.82BBR 2160
CAS:BBR 2160: a calcium-antagonist dihydropyridine derivative, reduces heart tissue contractility and shortens action potentials.Fórmula:C21H25N3O7SCor e Forma:SolidPeso molecular:463.5Ronipamil
CAS:Ronipamil is an analogue of verapamil that used as a calcium entry blocker.Fórmula:C32H48N2Cor e Forma:SolidPeso molecular:460.74Lercanidipine, (S)-
CAS:(S)-Lercanidipine: a dihydropyridine calcium blocker with prolonged antihypertensive and kidney-protective properties.Fórmula:C36H41N3O6Pureza:98%Cor e Forma:SolidPeso molecular:611.73Riodipine
CAS:Riodipine, a calcium channel blocker, is used as cardiovascular drugs.Fórmula:C18H19F2NO5Pureza:98%Cor e Forma:SolidPeso molecular:367.34Hexadecylphosphoserine
CAS:Hexadecylphosphoserine is a representative growth inhibitor.Fórmula:C19H40NO6PPureza:98%Cor e Forma:SolidPeso molecular:409.5SB-237376 HCl
CAS:SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias.Fórmula:C20H26ClN3O5Pureza:98.70%Cor e Forma:SolidPeso molecular:423.89Dopropidil hydrochloride
CAS:Dopropidil, a calcium channel antagonist, is used potentially for the treatment of arrhymia and angina pectoris.Fórmula:C20H36ClNO2Cor e Forma:SolidPeso molecular:357.96
