
Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 372 produtos de "Receptor GABA"
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Ethyl dirazepate
CAS:Ethyl dirazepate has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties,is a drug which is a benzodiazepine derivative.Fórmula:C18H14Cl2N2O3Pureza:98%Cor e Forma:SolidPeso molecular:377.22U-7524
CAS:U-7524 (AOAA), an inhibitor of GABA-T and other PLP-dependent enzymes, disrupts the Schiff base linkage, forming oxime complexes.Fórmula:C2H5NO3Cor e Forma:SolidPeso molecular:91.07Alfadolone
CAS:Alfadolone is an anesthetic derivative of pregnanedione.Fórmula:C21H32O4Cor e Forma:SolidPeso molecular:348.48Y 23684
CAS:Y-23684 is an anxiolytic drug with a novel chemical structure. It has similar effects to benzodiazepine drugs and is classed as a nonbenzodiazepine anxiolytic.Fórmula:C18H13ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:356.83Ro 22-8515
CAS:Ro 22-8515 is the ligand of benzodiazepine receptor.Fórmula:C18H12Cl2N2OCor e Forma:SolidPeso molecular:343.21Cyprodenate
CAS:Cyprodenate (Actebral) is a potent orally active brain-activating agent with appetite-suppressing properties, useful in studying metabolic.Fórmula:C13H25NO2Cor e Forma:SolidPeso molecular:227.34Ref: TM-T72977
1mg37,00€5mg72,00€10mg99,00€25mg169,00€50mg229,00€100mg320,00€200mg479,00€1mL*10mM (DMSO)79,00€ZK-91296
CAS:ZK-91296: GABA agonist, lowers anxiety without sedation, may target specific BZ receptor subtype.Fórmula:C23H22N2O4Pureza:98%Cor e Forma:SolidPeso molecular:390.43DS1
CAS:DS1 is a GABAA receptor agonist which can stimulate gonadotropin subunit gene expression in mouse.Fórmula:C18H10Br2ClN3OSCor e Forma:SolidPeso molecular:511.62SCH-50910 free base
CAS:SCH-50910 is an antagonist of GABAB receptor.Fórmula:C8H15NO3Cor e Forma:SolidPeso molecular:173.21Profadol hydrochloride
CAS:Profadol hydrochloride acts as a mixed agonist-antagonist of the μ-opioid receptor with analgesic activity.Fórmula:C14H22ClNOPureza:98%Cor e Forma:SolidPeso molecular:255.783-Methyl-GABA
CAS:3-Methyl-GABA activates GABA aminotransferase, fits GABAaR, stimulates GAD, and acts as an anticonvulsant.Fórmula:C20H30N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:522.59Ro15-4513
CAS:Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.Fórmula:C15H14N6O3Pureza:98%Cor e Forma:SolidPeso molecular:326.31Ro 14-7437
CAS:Ro 14-7437 is an antagonist of GABA-benzodiazepine receptor.Fórmula:C15H15N3O3Cor e Forma:SolidPeso molecular:285.3Adinazolam Mesylate
CAS:Adinazolam Mesylate is an anxiolytic and antidepressant agent. Adinazolam Mesylate binds to peripheral-type benzodiazepine receptors that interact allosterically with GABA receptors as an agonist to produce inhibitory effects.Fórmula:C20H22ClN5O3SPureza:98%Cor e Forma:SolidPeso molecular:447.94Ro 15-1310
CAS:Ro 15-3505, a benzodiazepine receptor partial inverse agonist, has shown the ability to improve impaired recent memory of aged mice.Fórmula:C15H14ClN3O3Cor e Forma:SolidPeso molecular:319.742-Hydroxysaclofen
CAS:2-Hydroxysaclofen is a GABAB receptor antagonist.Fórmula:C9H12ClNO4SPureza:98.56%Cor e Forma:White SolidPeso molecular:265.71CGS 20625
CAS:partial agonist for the benzodiazepine binding site of the GABAA receptorFórmula:C18H19N3O2Pureza:99.61%Cor e Forma:SolidPeso molecular:309.36SX-3228
CAS:SX-3228 is a selective agonist of benzodiazepine1 (BZ1) receptor(IC50 of 17 nM).Fórmula:C18H18N4O3Pureza:98%Cor e Forma:SolidPeso molecular:338.36CP-457920
CAS:CP-457920 is a selective α5 GABAA receptor inverse agonist that is suitable for investigating dementia in Alzheimer's disease.Fórmula:C18H17N3O3Pureza:99.06% - 99.74%Cor e Forma:SolidPeso molecular:323.35Org 20599
CAS:GABAA receptor agonistFórmula:C25H40ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:438.04U-101017
CAS:U-101017 is a partial benzodiazepine receptor and GABAA receptor agonist.Fórmula:C23H27ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:442.94TPA-023B
CAS:TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.Fórmula:C21H15F2N5OPureza:98%Cor e Forma:SolidPeso molecular:391.37CGP 7930
CAS:Positive allosteric modulator of GABAB receptorsFórmula:C19H32O2Pureza:98%Cor e Forma:SolidPeso molecular:292.46SCH 50911 hydrochloride
CAS:SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).Fórmula:C8H16ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:209.67BHF-177
CAS:BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.Fórmula:C19H20F3N3Cor e Forma:SolidPeso molecular:347.38CGS8216
CAS:CGS8216 shows analgesic activity at high doses, has anxiolytic activity, and can be used to study immune system disorders.Fórmula:C16H11N3OPureza:98.53%Cor e Forma:SolidPeso molecular:261.28DS2
CAS:Positive allosteric modulator of δ-subunit containing GABAA receptorsFórmula:C18H12ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:353.83(±)-Homoproline Hydrochloride
CAS:(±)-Homoproline Hydrochloride. Affordable Excellence: Reliable Quality You Can TrustFórmula:C6H12ClNO2Pureza:99.69%Cor e Forma:SolidPeso molecular:165.62MK-0343
CAS:MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.Fórmula:C19H17F2N7OPureza:98%Cor e Forma:SolidPeso molecular:397.3817-PA
CAS:17-PA is a GABAA receptor antagonist.Fórmula:C25H34OPureza:98%Cor e Forma:SolidPeso molecular:350.54Bifenazate
CAS:Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.Fórmula:C17H20N2O3Pureza:99.62%Cor e Forma:Solid CrystallinePeso molecular:300.35CGP11952
CAS:CGP11952 is same the benzodiazepines in its pharmacological action and it also is an experimental benzodiazepine derivative.Fórmula:C21H21Cl2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:446.33E2730
CAS:E2730 is a non-competitive GABA transporter 1 (GAT1) inhibitor with anti-epileptic activity, useful in studying neurological disorders.Fórmula:C9H8F4N2O2SPureza:98.22% - 98.54%Cor e Forma:SolidPeso molecular:284.23U-89843A
CAS:U-89843A is an allosteric modulator of the GABA_A receptor, known to enhance GABA-induced Cl^- currents [1].Fórmula:C16H24ClN5Pureza:98%Cor e Forma:SolidPeso molecular:321.85(R)-Baclofen hydrochloride
CAS:Arbaclofen HCl, a GABA-B agonist, treats spasticity from spinal injury by reducing excitatory transmission.Fórmula:C10H13Cl2NO2Pureza:98%Cor e Forma:SolidPeso molecular:250.12NO 711
CAS:NO 711(NNC-711 free acid) is a selective inhibitor of GAT-1, which enhances non-rapid eye movement sleep, and prevents paclitaxel-induced neuropathic pain.Fórmula:C21H22N2O3Pureza:99.70%Cor e Forma:SolidPeso molecular:350.41AZD 3043
CAS:AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.Fórmula:C19H29NO5Pureza:98.19% - 99.55%Cor e Forma:SolidPeso molecular:351.44mGAT3/4-IN-1
CAS:mGAT3/4-IN-1 inhibits mGAT3/4 with pIC50: 5.31/5.24, reduces neuropathic pain in diabetic mice.Fórmula:C26H31ClN2O2S2Cor e Forma:SolidPeso molecular:503.12GABAA receptor agent 4
CAS:Compound 1e is a potent γ-GABAAR antagonist with a Ki of 0.18 µM, offering immunomodulatory effects on T cell proliferation.Fórmula:C17H24N2OCor e Forma:SolidPeso molecular:272.39GABAA receptor agent 6
CAS:GABAA receptor agent 6 (compound 2027) is a potent γ-GABAAR antagonist with low cellular membrane permeability (Ki = 0.56 μM) [1].Fórmula:C18H25N3O2Cor e Forma:SolidPeso molecular:315.41TB 21007
CAS:GABAA receptor inverse agonistFórmula:C15H17NO2S3Pureza:98%Cor e Forma:SolidPeso molecular:339.5SL-651498
CAS:SL-651498, a GABAA receptor agonist, is used potentially for the treatment of anxiety.Fórmula:C23H20FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:389.42Bamaluzole
CAS:Bamaluzole is an agonist of GABA receptor.Fórmula:C14H12ClN3OPureza:98%Cor e Forma:SolidPeso molecular:273.72Ro 19-4603
CAS:Benzodiazepine inverse agonistFórmula:C15H17N3O3SPureza:98%Cor e Forma:SolidPeso molecular:319.38NAP-1
CAS:NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).Fórmula:C20H18ClNO2Cor e Forma:SolidPeso molecular:339.82GABAA receptor agent 7
CAS:Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.Fórmula:C18H13ClN4OCor e Forma:SolidPeso molecular:336.77MRK-623
CAS:MRK-623 (14k) is an oral GABA A agonist with high affinity for α1/α2/α3/α5 subunits and anxiolytic properties.Fórmula:C20H17FN4OCor e Forma:SolidPeso molecular:348.37Lesogaberan
CAS:Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).Fórmula:C3H9FNO2PPureza:98%Cor e Forma:SolidPeso molecular:141.08FG8119
CAS:FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.Fórmula:C17H15N5O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:321.33TG41
CAS:TG41 is a GABAA receptors positive modulator.Fórmula:C18H13BrCl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:440.12Etbicyphat
CAS:Etbicyphat: potent GABA(A) antagonist, induces epileptiform activity, binds to GABA/benzodiazepine receptors.Fórmula:C6H11O4PCor e Forma:SolidPeso molecular:178.12TCS 1105
CAS:TCS 1105 is a GABAA BZR ligand, blocking Sema3A and altering mouse anxiety, aggression, and social dominance.Fórmula:C17H13FN2O2Pureza:99.75%Cor e Forma:SolidPeso molecular:296.3Pipazethate
CAS:Pipipyrazine is a nonnarcotic oral cough suppressant, cough suppressant.Fórmula:C21H25N3O3SCor e Forma:SolidPeso molecular:399.51NNC052090
CAS:NNC052090 inhibits GABA uptake, favoring hBGT-1 (Ki=1.4μM), affects α1/D2 receptors (IC50=266/1632nM).Fórmula:C27H30N2O2Cor e Forma:SolidPeso molecular:414.54RU 33965
CAS:RU 33965, a 3-cyclopropyl carbonyl imidazobenzodiazepine, act as a low-efficacy benzodiazepine receptor inverse agonist.Fórmula:C16H15N3O2Pureza:98%Cor e Forma:SolidPeso molecular:281.31ZAPA sulfate
CAS:GABAA receptors agonistFórmula:C4H8N2O6S2Pureza:98%Cor e Forma:SolidPeso molecular:244.25ZK93423
CAS:ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.Fórmula:C23H22N2O4Cor e Forma:SolidPeso molecular:390.43NCS-382
CAS:γ-Hydroxybutyric acid antagonistFórmula:C13H14O3Pureza:98%Cor e Forma:SolidPeso molecular:218.25GABAA receptor modulator-2
CAS:Compound 20: Selective, oral α5-GABAAR inhibitor, Ki: 4.1 nM. High stability, CNS safe.Fórmula:C22H22FN3O5SCor e Forma:SolidPeso molecular:459.49Carburazepam
CAS:Carburazepam is a derivate of benzodiazepines. Benzodiazepines are a class of psychoactive drugs.Fórmula:C17H16ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:329.78UMB68 sodium
CAS:UMB-68 is a GHB receptor ligand with no affinity (IC(50) >100 microM) at GABA(A) or GABA(B) receptors.Fórmula:C6H12NaO3Cor e Forma:SolidPeso molecular:155.149β-CCB
CAS:benzodiazepine receptor ligandFórmula:C16H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:268.31GABAA receptor agent 8
CAS:Compound 5e, a GABAA receptor modulator, shows potent anticonvulsant effects with low neurotoxicity for epilepsy research.Fórmula:C19H16N4OCor e Forma:SolidPeso molecular:316.36Pregabalin arenacarbil
CAS:Pregabalin arenacarbil is a gabamimetic.Fórmula:C15H27NO6Cor e Forma:SolidPeso molecular:317.38CGP 36216 hydrochloride
CAS:CGP 36216 hydrochloride is a potent and selective antagonist of GABAB receptors (IC50: 43 μM).Fórmula:C5H14NO2PPureza:98%Cor e Forma:SolidPeso molecular:151.14(+)-Nipecotic acid
CAS:(+)-Nipecotic acid ((+)-β-Homoproline) is a specific inhibitor of GABA transport and uptake, capable of activating GABAA receptors.Fórmula:C6H11NO2Pureza:99.38%Cor e Forma:SolidPeso molecular:129.16Tracazolate hydrochloride
CAS:Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.Fórmula:C16H25ClN4O2Pureza:99.52%Cor e Forma:SolidPeso molecular:340.85GABA-AT-IN-1
CAS:GABA-AT-IN-1 (Compound 6) is an inhibitor of γ-aminobutyric acid transaminase (GABA-AT) that crosses the blood-brain barrier.Fórmula:C23H18N2O6Cor e Forma:SolidPeso molecular:418.4(S)-SNAP5114
CAS:(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.Fórmula:C30H35NO6Pureza:98.20%Cor e Forma:SolidPeso molecular:505.6Ref: TM-T16831
5mg49,00€10mg73,00€25mg152,00€50mg213,00€100mg309,00€200mg423,00€1mL*10mM (DMSO)49,00€Radequinil
CAS:Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).Fórmula:C18H14N4O3Pureza:98%Cor e Forma:SolidPeso molecular:334.333α,21-Dihydroxy-5α-pregnan-20-one
CAS:3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a GABAA modulator that can be used in the study of Alzheimer's-like neurological diseases.Fórmula:C21H34O3Pureza:98.00%Cor e Forma:SolidPeso molecular:334.49Phaclofen
CAS:GABAB antagonistFórmula:C9H13ClNO3PPureza:99.32%Cor e Forma:White SolidPeso molecular:249.63CCD-3693
CAS:CCD-3693 is a gamma-aminobutyric acid (GABA) receptor agonist.Fórmula:C21H31F3O2Pureza:98%Cor e Forma:SolidPeso molecular:372.46HZ166
CAS:HZ-166 is a positive GABAA receptor modulator and a GABAA receptor subtype-selective benzodiazepine site ligand.Fórmula:C21H16N4O2Pureza:98%Cor e Forma:SolidPeso molecular:356.38Chlormethiazole edisylate
CAS:Chlormethiazole edisylate is a positive allosteric modulator of the GABAA receptor. Chlormethiazole edisylate is a sedative and hypnotic.Fórmula:C8H14ClNO6S3Pureza:98%Cor e Forma:SolidPeso molecular:351.85COR628
CAS:COR628 is the GABA(B) receptor positive allosteric modulator.Fórmula:C16H23NO3SCor e Forma:SolidPeso molecular:309.42trans-4-Hydroxycrotonic acid
CAS:trans-4-Hydroxycrotonic acid (T-HCA) is a selective and competitive ligand for the γ-hydroxybutyric acid (GHB) binding site.Fórmula:C4H6O3Pureza:99.19%Cor e Forma:SolidPeso molecular:102.09LY 81067
CAS:LY 81067, a new anticonvulsant, prevents PTZ- and picrotoxin-induced seizures in mice via picrotoxin site interaction.Fórmula:C22H24N4OCor e Forma:SolidPeso molecular:360.45COR627
CAS:COR627 is the GABA receptor positive allosteric modulator.Fórmula:C20H27NO3SPureza:98%Cor e Forma:SolidPeso molecular:361.5CPP-115
CAS:CPP-115 is a GABA-aminotransferase inhibitor and a high-affinity vigabatrin analogue.Fórmula:C7H9F2NO2Cor e Forma:SolidPeso molecular:177.15JY-XHe-053
CAS:JY-XHe-053 is a selective modulator of GABAA receptors.Fórmula:C22H16FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:373.38HIE-124
CAS:HIE-124 is a central cervous system active anticonvulsant and ultra-short acting hypnotic.Fórmula:C10H12N2O3SPureza:98%Cor e Forma:SolidPeso molecular:240.28Suclofenide
CAS:Suclofenide: a benzenesulfonamide anticonvulsant, effective in mouse seizure models, with side effects like lethargy and diarrhea.Fórmula:C16H13ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:364.8(S)-Baclofen
CAS:(S)-Baclofen may treat hyperacusis and tinnitus by reducing auditory pathway excitation.Fórmula:C10H12ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:213.66Suriclone
CAS:Suriclone (RP 31264), a cyclic pyrrolidone for anxiety, modulates GABA-A receptors without major sedation.Fórmula:C20H20ClN5O3S2Pureza:99.21% - 99.73%Cor e Forma:SolidPeso molecular:477.99Ru-32514
CAS:Ru-32514 is a benzodiazepine receptor agonist.Fórmula:C18H17N3O2Pureza:99.21%Cor e Forma:SolidPeso molecular:307.35Divaplon
CAS:Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.Fórmula:C17H17N3O2Pureza:97.44% - 98.25%Cor e Forma:SolidPeso molecular:295.34DMCM hydrochloride
CAS:DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.Fórmula:C17H19ClN2O4Pureza:99.56%Cor e Forma:SolidPeso molecular:350.8Ref: TM-T11061
1mg34,00€2mg50,00€5mg80,00€10mg105,00€25mg236,00€50mg439,00€100mg620,00€1mL*10mM (DMSO)88,00€Sarmazenil
CAS:Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor and is used in the study of chronic hepatic encephalopathy.Fórmula:C15H14ClN3O3Pureza:99.46%Cor e Forma:SolidPeso molecular:319.74Muscimol HBr
CAS:Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.Fórmula:C4H7BrN2O2Pureza:98.13%Cor e Forma:Off-White PowderPeso molecular:195.01Ref: TM-T20657
1mg113,00€2mg169,00€5mg240,00€10mg385,00€25mg622,00€50mg898,00€100mg1.198,00€500mg2.422,00€1mL*10mM (DMSO)205,00€DSP-0565
CAS:DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.Fórmula:C14H12FNOPureza:99.51% - 99.56%Cor e Forma:SolidPeso molecular:229.25Ref: TM-T11106
1mg109,00€2mg163,00€5mg241,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.035,00€1mL*10mM (DMSO)208,00€ELB-139
CAS:ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.Fórmula:C14H16ClN3OPureza:>99.99%Cor e Forma:SolidPeso molecular:277.75Lirequinil
CAS:Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.Fórmula:C26H25ClN2O3Pureza:98.54%Cor e Forma:SolidPeso molecular:448.94L-838417
CAS:L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator used in the study of anxiety disordersFórmula:C19H19F2N7OPureza:98.12% - 99.70%Cor e Forma:SolidPeso molecular:399.4NNC 05-711
CAS:NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.Fórmula:C21H23ClN2O3Pureza:99.92%Cor e Forma:SolidPeso molecular:386.87Riluzole hydrochloride
CAS:Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).Fórmula:C8H6ClF3N2OSPureza:99.76%Cor e Forma:SolidPeso molecular:270.66Panadiplon
CAS:Panadiplon (FG 10571) is a selective gamma-aminobutyric acid receptor agonist and partial agonist of 5GABAA, a benzodiazepine receptor, used in the treatment ofFórmula:C18H17N5O2Pureza:98.30% - 98.94%Cor e Forma:SolidPeso molecular:335.36
