Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 373 produtos de "Receptor GABA"
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Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Cor e Forma:Odour SolidCAY10787
CAS:CAY10787, an oxysterol, inhibits GABAA receptors (IC50s: 1-1.5μM) and lessens GABA responses in mouse DRG neurons.Fórmula:C27H42OCor e Forma:SolidPeso molecular:382.632GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Fórmula:C18H22O2Cor e Forma:SolidPeso molecular:270.37RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFórmula:C42H39F6N5O2P2RuPureza:98%Cor e Forma:SolidPeso molecular:922.8CGP 35348
CAS:CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。Fórmula:C8H20NO4PPureza:≥98%Cor e Forma:SolidPeso molecular:225.22Antidepressant agent 3
Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.Fórmula:C17H30ClN5O2SCor e Forma:SolidPeso molecular:403.97Riluzole-13C,15N2
CAS:Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.Fórmula:CC7H5F3OS15N2Cor e Forma:SolidPeso molecular:237.18(Iso)-Atagabalin HCl
CAS:(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.Fórmula:C10H20ClNO2Pureza:99.88% - >99.99%Cor e Forma:SoildPeso molecular:221.72Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Fórmula:C12H10ClN2NaO5SPureza:99.52% - >99.99%Cor e Forma:SolidPeso molecular:352.73Flufiprole
CAS:Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.Fórmula:C16H10Cl2F6N4OSCor e Forma:SolidPeso molecular:491.24Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.Fórmula:C19H38ClN5O2SCor e Forma:SolidPeso molecular:436.06Nitrazolam
CAS:Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Fórmula:C17H13N5O2Cor e Forma:SolidPeso molecular:319.32GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Fórmula:C15H17BrO4SCor e Forma:SolidPeso molecular:373.265α-Androst-16-en-3α-ol
CAS:5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFórmula:C19H30OCor e Forma:SolidPeso molecular:274.448Guvacine hydrobromide
CAS:Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Fórmula:C6H10BrNO2Pureza:98%Cor e Forma:SolidPeso molecular:208.05Etifoxine
CAS:Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.Fórmula:C17H17ClN2OPureza:98%Cor e Forma:SolidPeso molecular:300.78CGP 36742
CAS:CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).Fórmula:C7H18NO2PCor e Forma:SolidPeso molecular:179.2Valnoctamide
CAS:Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.Fórmula:C8H17NOPureza:98%Cor e Forma:SolidPeso molecular:143.23Vigabatrin Hydrochloride
CAS:Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.Fórmula:C6H11NO2·HClPureza:98%Cor e Forma:SolidPeso molecular:165.62
