Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 336 produtos de "Receptor GABA"
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Furosemide sodium
CAS:<p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>Fórmula:C12H10ClN2NaO5SPureza:99.52% - >99.99%Cor e Forma:SolidPeso molecular:352.73Withasomniferolide B
CAS:<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Fórmula:C28H36O4Cor e Forma:SolidPeso molecular:436.58Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Cor e Forma:Odour SolidCGP 35348
CAS:<p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>Fórmula:C8H20NO4PPureza:≥98%Cor e Forma:SolidPeso molecular:225.22Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Fórmula:C17H30ClN5O2SCor e Forma:SolidPeso molecular:403.97Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Fórmula:C9H6Cl6O3SPureza:99.86%Cor e Forma:SolidPeso molecular:406.93Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Cor e Forma:Odour SolidAnticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Fórmula:C22H24N4O2Cor e Forma:SolidPeso molecular:376.45Nipecotic acid
CAS:<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C6H11NO2Cor e Forma:Off-White To Pale Yellow-Beige PowderPeso molecular:129.16α-Casozepine
CAS:<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Fórmula:C60H94N14O16Cor e Forma:SolidPeso molecular:1267.47Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Fórmula:C10H19NO2Cor e Forma:SolidPeso molecular:185.26Brexanolone caprilcerbate
CAS:<p>Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.</p>Fórmula:C48H78O12Cor e Forma:SolidPeso molecular:847.13Inaperisone
CAS:<p>Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.</p>Fórmula:C16H23NOPureza:99.48%Cor e Forma:SolidPeso molecular:245.36MIDD0301
CAS:<p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>Fórmula:C19H13BrFN3O2Pureza:98%Cor e Forma:SolidPeso molecular:414.233-Aminopropylphosphonic Acid
CAS:<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Fórmula:C3H10NO3PPureza:99.84%Cor e Forma:Light Yellow LiquidPeso molecular:139.09epi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48Cinazepam
CAS:<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Fórmula:C19H14BrClN2O5Cor e Forma:SolidPeso molecular:465.68GABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Fórmula:C15H17BrO4SCor e Forma:SolidPeso molecular:373.26GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Fórmula:C18H22O2Cor e Forma:SolidPeso molecular:270.37FGIN-1-43
CAS:<p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>Fórmula:C28H36Cl2N2OPureza:99.57%Cor e Forma:SolidPeso molecular:487.56,7-dimethylisatin
CAS:<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Fórmula:C10H9NO2Pureza:98.98%Cor e Forma:SolidPeso molecular:175.1812,14-Dichlorodehydroabietic acid
CAS:<p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>Fórmula:C20H26Cl2O2Cor e Forma:SolidPeso molecular:369.33Fipronil sulfone
CAS:<p>Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.</p>Fórmula:C12H4Cl2F6N4O2SPureza:98%Cor e Forma:SolidPeso molecular:453.14Chrodrimanin B
CAS:<p>Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.</p>Fórmula:C27H32O8Cor e Forma:SolidPeso molecular:484.545(Iso)-Atagabalin HCl
CAS:<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Fórmula:C10H20ClNO2Pureza:99.26% - >99.99%Cor e Forma:SoildPeso molecular:221.72Riluzole-13C,15N2
CAS:<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Fórmula:CC7H5F3OS15N2Cor e Forma:SolidPeso molecular:237.18Lesogaberan napadisylate
CAS:<p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>Fórmula:C13H17FNO5PSCor e Forma:SolidPeso molecular:349.31GABA-A Receptor Ligand-1
<p>GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.</p>Fórmula:C20H20FN3OCor e Forma:SolidPeso molecular:337.391Furosemide
CAS:<p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>Fórmula:C12H11ClN2O5SPureza:99.32% - 99.89%Cor e Forma:Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Peso molecular:330.744RuBi-GABA
CAS:<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Fórmula:C42H39F6N5O2P2RuPureza:98%Cor e Forma:SolidPeso molecular:922.8(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:<p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>Fórmula:C6H11NO2Cor e Forma:SolidPeso molecular:129.16Etifoxine
CAS:<p>Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.</p>Fórmula:C17H17ClN2OPureza:98%Cor e Forma:SolidPeso molecular:300.78Padsevonil
CAS:<p>Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.</p>Fórmula:C14H14ClF5N4O2SPureza:99.63%Cor e Forma:SolidPeso molecular:432.80MRK-016
CAS:<p>MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, orally available and penetrating the BBB. MRK-016 is antidepressant.</p>Fórmula:C17H20N8O2Pureza:99.76%Cor e Forma:SolidPeso molecular:368.39Propanidid
CAS:<p>Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and an intravenous anesthetic that lowers arterial blood pressure.</p>Fórmula:C18H27NO5Pureza:99.64%Cor e Forma:SolidPeso molecular:337.41Valnoctamide
CAS:<p>Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.</p>Fórmula:C8H17NOPureza:98%Cor e Forma:SolidPeso molecular:143.23Vigabatrin Hydrochloride
CAS:<p>Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.</p>Fórmula:C6H11NO2·HClPureza:98%Cor e Forma:SolidPeso molecular:165.62Dipropofol
CAS:<p>Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.</p>Fórmula:C24H34O2Pureza:99.51%Cor e Forma:SolidPeso molecular:354.53L-655708
CAS:<p>L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.</p>Fórmula:C18H19N3O4Pureza:98.41%Cor e Forma:PowderPeso molecular:341.36CGP 36742
CAS:<p>CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).</p>Fórmula:C7H18NO2PCor e Forma:SolidPeso molecular:179.2(-)-α-Pinene
CAS:<p>(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission,</p>Fórmula:C10H16Pureza:98.02% - 98.60%Cor e Forma:Colourless LiquidPeso molecular:136.23Furosemide-d5
CAS:<p>Furosemide-d5 is a deuterium marker for Furosemide and used in isotope tracer experiments. orally active inhibitor of Na+/K+/2Cl- (NKCC) diuretic reagent.</p>Fórmula:C12H11ClN2O5SCor e Forma:SolidPeso molecular:335.78Ocinaplon
CAS:<p>Ocinaplon (DOV 273547) is a GABAA receptors modulator.</p>Fórmula:C17H11N5OPureza:99.81%Cor e Forma:SolidPeso molecular:301.3Isoflurane
CAS:<p>Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation.</p>Fórmula:C3H2ClF5OPureza:98%Cor e Forma:Clear Colorless Liquid LiquidPeso molecular:184.49Ginkgolide A
CAS:<p>Ginkgolide A (BN-52020), from Ginkgo biloba leaves, is an active PAF antagonist with potential in treating inflammation and immune disorders.</p>Fórmula:C20H24O9Pureza:98.76% - 99.81%Cor e Forma:White PowderPeso molecular:408.4Imidazenil
CAS:<p>Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.</p>Fórmula:C18H12BrFN4OPureza:98.4%Cor e Forma:SolidPeso molecular:399.22γ-Acetylenic GABA
CAS:<p>γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase.</p>Fórmula:C6H9NO2Cor e Forma:SolidPeso molecular:127.1434-Acetamidobutanoic acid
CAS:<p>4-Acetamidobutanoic acid, a GABA derivative in eukaryotes, found in blood, feces, urine, and human prostate.</p>Fórmula:C6H11NO3Pureza:98.51%Cor e Forma:SolidPeso molecular:145.16(R)-baclofen
CAS:<p>(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.</p>Fórmula:C10H12ClNO2Pureza:97.20% - 98.94%Cor e Forma:SolidPeso molecular:213.66
