Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 363 produtos para "Receptor GABA".
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CGP 36742
CAS:CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).Fórmula:C7H18NO2PCor e Forma:SolidPeso molecular:179.2Vigabatrin Hydrochloride
CAS:Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.Fórmula:C6H11NO2·HClPureza:98%Cor e Forma:SolidPeso molecular:165.62Valnoctamide
CAS:Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.Fórmula:C8H17NOPureza:98%Cor e Forma:SolidPeso molecular:143.23DL-Menthol
CAS:DL-Menthol ((±)-Menthol) is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis.Fórmula:C10H20OPureza:99.16% - 99.74%Cor e Forma:White Crystals /89-78-1/ Physical Description White Crystalline Solid With A Peppermint Odor And Taste (Ntp 1992)Peso molecular:156.27Neurotensin TFA
Neurotensin TFA (39379-15-2) is a 13-amino acid neuropeptide with opioid-independent pain relief, acting in the CNS and gut, linked to numerous disorders.Fórmula:C80H122F3N21O22Pureza:99.41%Cor e Forma:White SolidPeso molecular:1786.98Ocinaplon
CAS:Ocinaplon (DOV 273547) is a GABAA receptors modulator.Fórmula:C17H11N5OPureza:99.81%Cor e Forma:SolidPeso molecular:301.3Gabazine free base
CAS:Gabazine free base is a specific antagonist of the GABA receptor. It does not affect GABA-transaminase or glutamate-decarboxylase activities.Fórmula:C15H17N3O3Cor e Forma:SolidPeso molecular:287.31Ginkgolide A
CAS:Ginkgolide A (BN-52020), from Ginkgo biloba leaves, is an active PAF antagonist with potential in treating inflammation and immune disorders.Fórmula:C20H24O9Pureza:98.76% - 99.81%Cor e Forma:White SolidPeso molecular:408.406-Methylflavone
CAS:6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.Fórmula:C16H12O2Pureza:99.69%Cor e Forma:White SolidPeso molecular:236.27Saclofen
CAS:Saclofen is a GABA analog and GABAB receptor antagonist, useful for studying inhibitory brain signals. IC50: 7.8 μM.Fórmula:C9H12ClNO3SPureza:99.17%Cor e Forma:SolidPeso molecular:249.71Ref: TM-T4440
1mg52,00€1mL*10mM (DMSO)108,00€5mg113,00€10mg177,00€25mg340,00€50mg550,00€100mg860,00€200mg1.161,00€Baclofen hydrochloride
CAS:Baclofen HCL, a GABA-B agonist, treats muscle spasticity by reducing excitatory transmission.Fórmula:C10H13Cl2NO2Pureza:99.55%Cor e Forma:SolidPeso molecular:250.122γ-Acetylenic GABA
CAS:γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase.Fórmula:C6H9NO2Cor e Forma:SolidPeso molecular:127.143(+)-Kavain
CAS:(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.Fórmula:C14H14O3Pureza:97% - ≥95%Cor e Forma:SolidPeso molecular:230.26Phenibut (hydrochloride)
CAS:Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors.Fórmula:C10H14ClNO2Pureza:99.93%Cor e Forma:White SolidPeso molecular:215.68Thiocolchicoside
CAS:Thiocolchicoside, a muscle relaxant, has anti-inflammatory and analgesic properties; not for seizure-prone people.Fórmula:C27H33NO10SPureza:99.11% - 99.39%Cor e Forma:SolidPeso molecular:563.62(-)-Securinine
CAS:(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.Fórmula:C13H15NO2Pureza:99.58% - 99.87%Cor e Forma:Yellow SolidPeso molecular:217.26Imepitoin
CAS:Imepitoin (AWD 131-138), a new low-affinity partial benzodiazepine receptor agonist, shows potent anticonvulsant and anxiolytic properties in rodent models.Fórmula:C13H14ClN3O2Pureza:99.82%Cor e Forma:SolidPeso molecular:279.72Tiagabine hydrochloride
CAS:Tiagabine hydrochloride, a nipecotic acid derivative, is an anticonvulsant and selective GABA reuptake inhibitor.Fórmula:C20H25NO2S2·HClPureza:99.09% - 99.77%Cor e Forma:SolidPeso molecular:412.016-(4-Methoxyphenyl)-3-pyridazinamine
CAS:6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonistFórmula:C11H11N3OPureza:99.03%Cor e Forma:Yellow SolidPeso molecular:201.22L-838417-D9
CAS:L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].Fórmula:C19H10D9F2N7OPureza:99.65%Cor e Forma:SolidPeso molecular:408.45(R)-baclofen
CAS:(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.Fórmula:C10H12ClNO2Pureza:97.20% - 98.94%Cor e Forma:White SolidPeso molecular:213.66Arecaidine hydrochloride
CAS:Arecaidine hydrochloride may have carcinogenesis.Fórmula:C7H12ClNO2Pureza:99.69% - ≥95%Cor e Forma:White SolidPeso molecular:177.63Ref: TM-T5799
2mg34,00€5mg48,00€1mL*10mM (DMSO)49,00€10mg67,00€25mg100,00€50mg149,00€100mg213,00€200mg316,00€Temgicoluril
CAS:Temgicoluril (mebikar) acts on GABA Receptor.Fórmula:C8H14N4O2Pureza:99.8%Cor e Forma:SolidPeso molecular:198.22SKF89976A HCl
CAS:SKF89976A: GABA uptake inhibitor, selective for GAT-1, passes blood-brain barrier, active in vivo (IC50: 0.13 μM hGAT-1).Fórmula:C22H25NO2Cor e Forma:SolidPeso molecular:335.44Gaboxadol hydrochloride
CAS:Gaboxadol (hydrochloride) is a GABAA receptor agonist.Fórmula:C6H9ClN2O2Pureza:98.43% - 99.39%Cor e Forma:White SolidPeso molecular:176.601Lorediplon
CAS:Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.Fórmula:C20H15FN4O2SPureza:99.12% - 99.19%Cor e Forma:SolidPeso molecular:394.42Gabazine
CAS:Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)Fórmula:C15H18BrN3O3Pureza:98.51% - 99.24%Cor e Forma:White SolidPeso molecular:368.23Pipequaline hydrochloride
CAS:Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative.Fórmula:C22H25ClN2Pureza:99.78%Cor e Forma:Yellow SolidPeso molecular:352.9(2S)-6-Prenylnaringenin
CAS:(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin.Fórmula:C20H20O5Pureza:99.47%Cor e Forma:SolidPeso molecular:340.37α-Thujone
CAS:α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Fórmula:C10H16OPureza:97.02% - 98.41%Cor e Forma:Transparent OilPeso molecular:152.23Piperazine citrate
CAS:Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring.Fórmula:C24H46N6O14Pureza:99.8%Cor e Forma:Crystals IndicationPeso molecular:642.652'-O-Methylisoliquiritigenin
CAS:2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-Fórmula:C16H14O4Pureza:98.75%Cor e Forma:SolidPeso molecular:270.28U93631
CAS:GABAA antagonist; binds picrotoxin site, stabilizes inactive channel. Speeds GABA-induced Cl- decay, minor peak effect. Inhibits 5-HT3A receptors.Fórmula:C17H21N3O2Pureza:99.65% - 99.76%Cor e Forma:SolidPeso molecular:299.37Ginsenoside Rc
CAS:Ginsenoside Rc (Panaxoside Rc) is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.Fórmula:C53H90O22Pureza:98.83% - 99.86%Cor e Forma:White SolidPeso molecular:1079.27Cholesterol myristate
CAS:Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.Fórmula:C41H72O2Pureza:99.65%Cor e Forma:White SolidPeso molecular:597.01Tiagabine
CAS:Tiagabine (NO050328) is an Anti-epileptic Agent.Fórmula:C20H25NO2S2Pureza:99.25% - 99.67%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:375.55Acetoxyvalerensre
CAS:Acetoxyvalerensre (acetylvalerenolic acid) (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.Fórmula:C17H24O4Pureza:98.22%Cor e Forma:SolidPeso molecular:292.37Fipronil
CAS:Produto ControladoFipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.Fórmula:C12H4Cl2F6N4OSPureza:97.21%Cor e Forma:White SolidPeso molecular:437.15SKF89976A hydrochloride
CAS:SKF89976A hydrochloride (d,l-SKF89976A hydrochloride) is a selective inhibitor GABA transporter such as GAT-1 (IC50s = 0.28 μM), GAT-2 (IC50s = 137.34 μM) andFórmula:C22H26ClNO2Pureza:98.02%Cor e Forma:SolidPeso molecular:371.9Ref: TM-T12930
1mg34,00€5mg65,00€1mL*10mM (DMSO)71,00€10mg89,00€25mg167,00€50mg264,00€100mg409,00€200mg590,00€α-Asarone
CAS:alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice.Fórmula:C12H16O3Pureza:99.64% - 99.64%Cor e Forma:SolidPeso molecular:208.25Miltirone
CAS:Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.Fórmula:C19H22O2Pureza:99.22% - 99.66%Cor e Forma:SolidPeso molecular:282.38Amentoflavone
CAS:Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.Fórmula:C30H18O10Pureza:98.81% - 99.78%Cor e Forma:Yellow SolidPeso molecular:538.46Ref: TM-T3417
2mg34,00€5mg50,00€1mL*10mM (DMSO)59,00€10mg80,00€25mg126,00€50mg215,00€100mg349,00€200mg512,00€AZD-6280
CAS:AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.Fórmula:C20H22N4O3Pureza:98.99%Cor e Forma:White SolidPeso molecular:366.41Ref: TM-T7136
1mg215,00€5mg439,00€1mL*10mM (DMSO)484,00€10mg640,00€25mg1.018,00€50mg1.423,00€100mg1.935,00€Songorine
CAS:Songorine (Napellonine) shows anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.Fórmula:C22H31NO3Pureza:98% - 99.92%Cor e Forma:White SolidPeso molecular:357.49CL 218872
CAS:CL 218872: selective α1 GABAA receptor agonist, anxiolytic, and anticonvulsant; Ki=130 nM for α1, less potent for α2-α6.Fórmula:C13H9F3N4Pureza:99.92%Cor e Forma:SolidPeso molecular:278.23Kavain
CAS:Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation ofFórmula:C14H14O3Pureza:99.93% - ≥95%Cor e Forma:SolidPeso molecular:230.26SSD114 HCl
CAS:SSD114 is a novel GABAB receptor positive allosteric modulator.Fórmula:C18H21ClF3N3OPureza:99.03% - 99.95%Cor e Forma:White SolidPeso molecular:387.83Ref: TM-T4522
2mg34,00€1mL*10mM (DMSO)46,00€5mg50,00€10mg75,00€25mg111,00€50mg172,00€100mg290,00€200mg419,00€2'MeO6MF
CAS:2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functionalFórmula:C17H14O3Pureza:99.28% - 99.63%Cor e Forma:White SolidPeso molecular:266.29Ref: TM-T8887
1mg49,00€1mL*10mM (DMSO)96,00€5mg102,00€10mg152,00€25mg243,00€50mg340,00€100mg460,00€200mg627,00€Tiagabine hydrochloride hydrate
CAS:Tiagabine HCl hydrate, IC50: 67-446 nM, selectively inhibits GABA uptake, acts as an anticonvulsant.Fórmula:C20H28ClNO3S2Cor e Forma:SolidPeso molecular:430.02rac-BHFF
CAS:rac-BHFF, a GABA B receptor modulator, boosts GABA potency >15x, efficacy >149%, has anxiolytic effects, and is orally active.Fórmula:C17H21F3O3Pureza:99.69% - >99.99%Cor e Forma:White SolidPeso molecular:330.34Ref: TM-T4176
2mg40,00€5mg57,00€1mL*10mM (DMSO)67,00€10mg90,00€25mg177,00€50mg295,00€100mg447,00€200mg622,00€
