Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 336 produtos de "Receptor GABA"
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Miltirone
CAS:<p>Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.</p>Fórmula:C19H22O2Pureza:99.22% - 99.66%Cor e Forma:SolidPeso molecular:282.38SKF89976A hydrochloride
CAS:<p>SKF89976A hydrochloride (d,l-SKF89976A hydrochloride) is a selective inhibitor GABA transporter such as GAT-1 (IC50s = 0.28 μM), GAT-2 (IC50s = 137.34 μM) and</p>Fórmula:C22H26ClNO2Pureza:98.02%Cor e Forma:SolidPeso molecular:371.9Piperazine
CAS:<p>Piperazine (1,4-Diazacyclohexane), a gamma-aminobutyric acid (GABA) agonist, serves as a crucial building block and core component in a wide range of marketed drugs known for their varied pharmacological activities.</p>Fórmula:C4H10N2Cor e Forma:SolidPeso molecular:86.14Ginkgolide A
CAS:<p>Ginkgolide A (BN-52020), from Ginkgo biloba leaves, is an active PAF antagonist with potential in treating inflammation and immune disorders.</p>Fórmula:C20H24O9Pureza:98.76% - 99.81%Cor e Forma:White PowderPeso molecular:408.4Imepitoin
CAS:<p>Imepitoin (AWD 131-138), a new low-affinity partial benzodiazepine receptor agonist, shows potent anticonvulsant and anxiolytic properties in rodent models.</p>Fórmula:C13H14ClN3O2Pureza:99.82%Cor e Forma:SolidPeso molecular:279.72Isonipecotic acid
CAS:<p>Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.</p>Fórmula:C6H11NO2Pureza:99.82%Cor e Forma:White To Faint Pink-Beige PowderPeso molecular:129.16Gabazine
CAS:<p>Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)</p>Fórmula:C15H18BrN3O3Pureza:98.51% - 99.24%Cor e Forma:SolidPeso molecular:368.23Tiagabine
CAS:<p>Tiagabine (NO050328) is an Anti-epileptic Agent.</p>Fórmula:C20H25NO2S2Pureza:99.25%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:375.55Acetoxyvalerensre
CAS:<p>Acetoxyvalerensre (acetylvalerenolic acid) (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.</p>Fórmula:C17H24O4Pureza:98.22%Cor e Forma:SolidPeso molecular:292.37Amentoflavone
CAS:<p>Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.</p>Fórmula:C30H18O10Pureza:98.21% - 99.22%Cor e Forma:Odourless Whitish SolidPeso molecular:538.46Aminooxyacetic acid hemihydrochloride
CAS:<p>Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride) is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA</p>Fórmula:C2H5NO3·5HClPureza:98.03%Cor e Forma:Light Beige Crystalline PowderPeso molecular:109.36-(4-Methoxyphenyl)-3-pyridazinamine
CAS:<p>6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist</p>Fórmula:C11H11N3OPureza:99.03%Cor e Forma:SolidPeso molecular:201.22Fipronil
CAS:<p>Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.</p>Fórmula:C12H4Cl2F6N4OSPureza:97.21%Cor e Forma:Solid PowderPeso molecular:437.15Darigabat
CAS:<p>Darigabat (PF-06372865) is a GABAA receptor modulator with anxiolytic activity that inhibits α2, α1 PAM, and α2 PAM.</p>Fórmula:C22H21FN4O3SPureza:98.42% - 99.29%Cor e Forma:SolidPeso molecular:440.49Riluzole
CAS:<p>Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.</p>Fórmula:C8H5F3N2OSPureza:99.71% - 99.88%Cor e Forma:PowderPeso molecular:234.2CGP 36216 hydrochloride
CAS:<p>CGP 36216 hydrochloride is a potent and selective antagonist of GABAB receptors (IC50: 43 μM).</p>Fórmula:C5H14NO2PPureza:98%Cor e Forma:SolidPeso molecular:151.14β-CCB
CAS:<p>benzodiazepine receptor ligand</p>Fórmula:C16H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:268.31NO 711
CAS:<p>NO 711（NNC-711 free acid） is a selective inhibitor of GAT-1, which enhances non-rapid eye movement sleep, and prevents paclitaxel-induced neuropathic pain.</p>Fórmula:C21H22N2O3Pureza:99.70%Cor e Forma:SolidPeso molecular:350.41(±)-Homoproline Hydrochloride
CAS:<p>(±)-Homoproline Hydrochloride. Affordable Excellence: Reliable Quality You Can Trust</p>Fórmula:C6H12ClNO2Pureza:99.69%Cor e Forma:SolidPeso molecular:165.62CP-457920
CAS:<p>CP-457920 is a selective α5 GABAA receptor inverse agonist that is suitable for investigating dementia in Alzheimer's disease.</p>Fórmula:C18H17N3O3Pureza:99.06% - 99.74%Cor e Forma:SolidPeso molecular:323.35Ro 41-3290
CAS:<p>Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is an agonist of nonbenzodiazepine partial at the benzodiazepine receptor.</p>Fórmula:C24H21ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:420.89PF-0713
CAS:<p>PF 0713, a GABAA receptor agonist, is used as an intravenous sedative-hypnotic for general anaesthesia, ICU sedation, procedural sedation, chemotherapy.</p>Fórmula:C14H22OPureza:98%Cor e Forma:SolidPeso molecular:206.32HZ166
CAS:<p>HZ-166 is a positive GABAA receptor modulator and a GABAA receptor subtype-selective benzodiazepine site ligand.</p>Fórmula:C21H16N4O2Pureza:98%Cor e Forma:SolidPeso molecular:356.38Pregabalin arenacarbil
CAS:<p>Pregabalin arenacarbil is a gabamimetic.</p>Fórmula:C15H27NO6Cor e Forma:SolidPeso molecular:317.38NCS-382
CAS:<p>γ-Hydroxybutyric acid antagonist</p>Fórmula:C13H14O3Pureza:98%Cor e Forma:SolidPeso molecular:218.25Ro 19-4603
CAS:<p>Benzodiazepine inverse agonist</p>Fórmula:C15H17N3O3SPureza:98%Cor e Forma:SolidPeso molecular:319.38GABAA receptor agent 4
CAS:<p>Compound 1e is a potent γ-GABAAR antagonist with a Ki of 0.18 µM, offering immunomodulatory effects on T cell proliferation.</p>Fórmula:C17H24N2OCor e Forma:SolidPeso molecular:272.39mGAT3/4-IN-1
CAS:<p>mGAT3/4-IN-1 inhibits mGAT3/4 with pIC50: 5.31/5.24, reduces neuropathic pain in diabetic mice.</p>Fórmula:C26H31ClN2O2S2Cor e Forma:SolidPeso molecular:503.12CGP11952
CAS:<p>CGP11952 is same the benzodiazepines in its pharmacological action and it also is an experimental benzodiazepine derivative.</p>Fórmula:C21H21Cl2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:446.3317-PA
CAS:<p>17-PA is a GABAA receptor antagonist.</p>Fórmula:C25H34OPureza:98%Cor e Forma:SolidPeso molecular:350.54MK-0343
CAS:<p>MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.</p>Fórmula:C19H17F2N7OPureza:98%Cor e Forma:SolidPeso molecular:397.38DS2
CAS:<p>Positive allosteric modulator of δ-subunit containing GABAA receptors</p>Fórmula:C18H12ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:353.83CGS8216
CAS:<p>CGS8216 shows analgesic activity at high doses, has anxiolytic activity, and can be used to study immune system disorders.</p>Fórmula:C16H11N3OPureza:98.53%Cor e Forma:SolidPeso molecular:261.28BHF-177
CAS:<p>BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.</p>Fórmula:C19H20F3N3Cor e Forma:SolidPeso molecular:347.38CGP 7930
CAS:<p>Positive allosteric modulator of GABAB receptors</p>Fórmula:C19H32O2Pureza:98%Cor e Forma:SolidPeso molecular:292.46TPA-023B
CAS:<p>TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.</p>Fórmula:C21H15F2N5OPureza:98%Cor e Forma:SolidPeso molecular:391.37U-101017
CAS:<p>U-101017 is a partial benzodiazepine receptor and GABAA receptor agonist.</p>Fórmula:C23H27ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:442.94Org 20599
CAS:<p>GABAA receptor agonist</p>Fórmula:C25H40ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:438.04SX-3228
CAS:<p>SX-3228 is a selective agonist of benzodiazepine1 (BZ1) receptor(IC50 of 17 nM).</p>Fórmula:C18H18N4O3Pureza:98%Cor e Forma:SolidPeso molecular:338.36CGS 20625
CAS:<p>partial agonist for the benzodiazepine binding site of the GABAA receptor</p>Fórmula:C18H19N3O2Pureza:99.61%Cor e Forma:SolidPeso molecular:309.362-Hydroxysaclofen
CAS:<p>2-Hydroxysaclofen is a GABAB receptor antagonist.</p>Fórmula:C9H12ClNO4SPureza:98%Cor e Forma:White SolidPeso molecular:265.71Ro15-4513
CAS:<p>Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.</p>Fórmula:C15H14N6O3Pureza:98%Cor e Forma:SolidPeso molecular:326.313-Methyl-GABA
CAS:<p>3-Methyl-GABA activates GABA aminotransferase, fits GABAaR, stimulates GAD, and acts as an anticonvulsant.</p>Fórmula:C20H30N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:522.59DS1
CAS:<p>DS1 is a GABAA receptor agonist which can stimulate gonadotropin subunit gene expression in mouse.</p>Fórmula:C18H10Br2ClN3OSCor e Forma:SolidPeso molecular:511.62Cyprodenate
CAS:<p>Cyprodenate (Actebral) is a potent orally active brain-activating agent with appetite-suppressing properties, useful in studying metabolic.</p>Fórmula:C13H25NO2Cor e Forma:SolidPeso molecular:227.34Y 23684
CAS:<p>Y-23684 is an anxiolytic drug with a novel chemical structure. It has similar effects to benzodiazepine drugs and is classed as a nonbenzodiazepine anxiolytic.</p>Fórmula:C18H13ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:356.83U-7524
CAS:<p>U-7524 (AOAA), an inhibitor of GABA-T and other PLP-dependent enzymes, disrupts the Schiff base linkage, forming oxime complexes.</p>Fórmula:C2H5NO3Cor e Forma:SolidPeso molecular:91.07Ethyl dirazepate
CAS:<p>Ethyl dirazepate has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties,is a drug which is a benzodiazepine derivative.</p>Fórmula:C18H14Cl2N2O3Pureza:98%Cor e Forma:SolidPeso molecular:377.22Arbaclofen placarbil
CAS:<p>Arbaclofen placarbil is a GABA(B) receptor agonist with better ADMET than R-baclofen, reducing postprandial reflux in GERD.</p>Fórmula:C19H26ClNO6Cor e Forma:SolidPeso molecular:399.87
