Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 372 produtos de "Receptor GABA"
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Isoflurane
CAS:Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation.Fórmula:C3H2ClF5OPureza:98%Cor e Forma:Clear Colorless Liquid LiquidPeso molecular:184.49Cyclothiazide
CAS:Cyclothiazide enhances AMPA receptors, prevents desensitization, and boosts glutamic acid response (EC50 = 3.8µM).Fórmula:C14H16ClN3O4S2Pureza:98.23% - 99.49%Cor e Forma:Crystals From Dilute Alcohol SolidPeso molecular:389.88SSD114 HCl
CAS:SSD114 is a novel GABAB receptor positive allosteric modulator.Fórmula:C18H21ClF3N3OPureza:99.03% - 99.95%Cor e Forma:SolidPeso molecular:387.83Ref: TM-T4522
2mg34,00€5mg50,00€10mg75,00€25mg111,00€50mg172,00€100mg290,00€200mg419,00€1mL*10mM (DMSO)46,00€p-Hydroxybenzaldehyde
CAS:1.Fórmula:C7H6O2Pureza:99.05% - 99.86%Cor e Forma:SolidPeso molecular:122.12Aminooxyacetic acid hemihydrochloride
CAS:Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride) is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABAFórmula:C2H5NO3·5HClPureza:98.03%Cor e Forma:Light Beige Crystalline PowderPeso molecular:109.3Amentoflavone
CAS:Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.Fórmula:C30H18O10Pureza:98.21% - 99.22%Cor e Forma:Odourless Whitish SolidPeso molecular:538.46Ref: TM-T3417
2mg34,00€5mg50,00€10mg80,00€25mg126,00€50mg215,00€100mg349,00€200mg512,00€1mL*10mM (DMSO)59,00€Tiagabine
CAS:Tiagabine (NO050328) is an Anti-epileptic Agent.Fórmula:C20H25NO2S2Pureza:99.25% - 99.67%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:375.55Gaboxadol hydrochloride
CAS:Gaboxadol (hydrochloride) is a GABAA receptor agonist.Fórmula:C6H9ClN2O2Pureza:99.39%Peso molecular:176.601SKF89976A HCl
CAS:SKF89976A: GABA uptake inhibitor, selective for GAT-1, passes blood-brain barrier, active in vivo (IC50: 0.13 μM hGAT-1).Fórmula:C22H25NO2Cor e Forma:SolidPeso molecular:335.44Gabazine
CAS:Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)Fórmula:C15H18BrN3O3Pureza:98.51% - 99.24%Cor e Forma:SolidPeso molecular:368.236-(4-Methoxyphenyl)-3-pyridazinamine
CAS:6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonistFórmula:C11H11N3OPureza:99.03%Cor e Forma:SolidPeso molecular:201.22L-838417 D9
CAS:L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].Fórmula:C19H10D9F2N7OPureza:99.65%Cor e Forma:SolidPeso molecular:408.45Ref: TM-T22301
2mg34,00€5mg52,00€10mg71,00€25mg128,00€50mg200,00€100mg323,00€200mg447,00€1mL*10mM (DMSO)58,00€2'-O-Methylisoliquiritigenin
CAS:2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-Fórmula:C16H14O4Pureza:98.75%Cor e Forma:SolidPeso molecular:270.28Baclofen hydrochloride
CAS:Baclofen HCL, a GABA-B agonist, treats muscle spasticity by reducing excitatory transmission.Fórmula:C10H13Cl2NO2Pureza:99.55%Cor e Forma:SolidPeso molecular:250.1226-Methylflavone
CAS:6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.Fórmula:C16H12O2Pureza:99.69%Cor e Forma:SolidPeso molecular:236.27Neurotensin TFA
Neurotensin TFA (39379-15-2) is a 13-amino acid neuropeptide with opioid-independent pain relief, acting in the CNS and gut, linked to numerous disorders.Fórmula:C80H122F3N21O22Pureza:99.41%Cor e Forma:SolidPeso molecular:1786.98DL-Menthol
CAS:DL-Menthol ((±)-Menthol) is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis.Fórmula:C10H20OPureza:99.74%Cor e Forma:White Crystals /89-78-1/ Physical Description White Crystalline Solid With A Peppermint Odor And Taste (Ntp 1992)Peso molecular:156.27Saclofen
CAS:Saclofen is a GABA analog and GABAB receptor antagonist, useful for studying inhibitory brain signals. IC50: 7.8 μM.Fórmula:C9H12ClNO3SPureza:99.17%Cor e Forma:White Crystalline SolidPeso molecular:249.71Ref: TM-T4440
1mg52,00€5mg113,00€10mg177,00€25mg340,00€50mg550,00€100mg860,00€200mg1.161,00€1mL*10mM (DMSO)108,00€Imepitoin
CAS:Imepitoin (AWD 131-138), a new low-affinity partial benzodiazepine receptor agonist, shows potent anticonvulsant and anxiolytic properties in rodent models.Fórmula:C13H14ClN3O2Pureza:99.82%Cor e Forma:SolidPeso molecular:279.72U93631
CAS:GABAA antagonist; binds picrotoxin site, stabilizes inactive channel. Speeds GABA-induced Cl- decay, minor peak effect. Inhibits 5-HT3A receptors.Fórmula:C17H21N3O2Pureza:99.65% - 99.76%Cor e Forma:SolidPeso molecular:299.37Fluralaner
CAS:Fluralaner (A1443) is an isoxazoline ectoparasiticide.Fórmula:C22H17Cl2F6N3O3Pureza:99.72% - 99.99%Cor e Forma:Solid PowderPeso molecular:556.29Ginsenoside Rc
CAS:Ginsenoside Rc (Panaxoside Rc) is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
Fórmula:C53H90O22Pureza:98.83% - 99.56%Cor e Forma:White PowderPeso molecular:1079.27NS11394
CAS:NS11394 is a effective and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of α(5) > α(3) > α(2) > α(Fórmula:C23H19N3OPureza:99.44% - 99.86%Cor e Forma:SolidPeso molecular:353.42Ref: TM-T2067
2mg34,00€5mg50,00€10mg80,00€25mg131,00€50mg212,00€100mg321,00€200mg460,00€1mL*10mM (DMSO)58,00€ONO-8590580
CAS:ONO-8590580 (CS-2894) is a negative allosteric modulator of GABAA α5.Fórmula:C21H21FN6Pureza:99.43%Cor e Forma:SolidPeso molecular:376.43Ref: TM-TQ0040
1mg57,00€5mg119,00€10mg166,00€25mg356,00€50mg532,00€100mg760,00€1mL*10mM (DMSO)133,00€Jujuboside A
CAS:Jujuboside A: glycoside from Semen Ziziphi Spinosae, may treat Alzheimer's, has neuro-inhibitory effects.Fórmula:C58H94O26Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:1207.35Suritozole
CAS:Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptorFórmula:C10H10FN3SPureza:99.25%Cor e Forma:SolidPeso molecular:223.27Ref: TM-T8568
1mg58,00€5mg116,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)104,00€Basmisanil
CAS:Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for theFórmula:C21H20FN3O5SPureza:99.21% - 99.42%Cor e Forma:SolidPeso molecular:445.46Ref: TM-T7165
2mg35,00€5mg52,00€10mg74,00€25mg116,00€50mg187,00€100mg356,00€500mg802,00€1mL*10mM (DMSO)49,00€Dihydroergotoxine mesylate
CAS:Dihydroergotoxine mesylate (Ergoloid mesylates) is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.Fórmula:C20H29N3O5SPureza:99.39% - ≥95%Cor e Forma:SolidPeso molecular:423.53Bicuculline
CAS:Bicuculline, a plant-derived GABAA receptor antagonist, identified in 1932, reacts to light.Fórmula:C20H17NO6Pureza:98% - 99.99%Cor e Forma:Light Yellow PowderPeso molecular:367.35Loreclezole
CAS:Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.Fórmula:C10H6Cl3N3Pureza:99.78%Cor e Forma:SolidPeso molecular:274.53Afloqualone
CAS:Afloqualone (HQ-495) is a GABA Receptor agonist with sedative and muscle-relaxant properties.Fórmula:C16H14FN3OPureza:99.72%Cor e Forma:SolidPeso molecular:283.3Riluzole
CAS:Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.Fórmula:C8H5F3N2OSPureza:99.71% - 99.88%Cor e Forma:PowderPeso molecular:234.2Darigabat
CAS:Darigabat (PF-06372865) is a GABAA receptor modulator with anxiolytic activity that inhibits α2, α1 PAM, and α2 PAM.Fórmula:C22H21FN4O3SPureza:98.42% - 99.29%Cor e Forma:SolidPeso molecular:440.49PNU-107484A
CAS:PNU-107484A is a unique GABA(A) receptor ligand.Fórmula:C18H23ClN6Pureza:98%Cor e Forma:SolidPeso molecular:358.87ABP-700
CAS:ABP-700 is a positive allosteric modulator of the GABAA receptor.Fórmula:C17H18N2O4Pureza:98%Cor e Forma:SolidPeso molecular:314.34DAA-1097
CAS:DAA-1097 is a novel ligand of peripheral benzodiazepine receptor.Fórmula:C24H24ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:409.91(S)-3-Carboxy-4-hydroxyphenylglycine
CAS:group I metabotropic glutamate receptor antagonist and group II mGlu agonistFórmula:C9H9NO5Pureza:98%Cor e Forma:SolidPeso molecular:211.17BGT1-IN-9
CAS:BGT1-IN-9 is an M1 muscarinic agonist.Fórmula:C5H10ClN3O2Cor e Forma:SolidPeso molecular:179.605GABAA receptor agent 5
CAS:Compound 018 is a potent γ-GABAAR antagonist, Ki of 0.020 μM, with low membrane permeability.Fórmula:C21H25N3O2SPureza:99.39%Cor e Forma:SolidPeso molecular:383.51CGP 46381
CAS:CGP 46381 is a GABAB receptor antagonist.Fórmula:C10H22NO2PPureza:98%Cor e Forma:White SolidPeso molecular:219.26RO 4938581
CAS:RO 4938581: potent GABAA α5 inverse agonist (Ki 4.6 nM); lower affinity for α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki: 174, 185, 80 nM).Fórmula:C13H8BrF2N5Pureza:98%Cor e Forma:SolidPeso molecular:352.14GS 39783
CAS:GS 39783 is a positive allosteric modulator (PAM) of GABABR, which reduces the motivational properties of alcohol and the conditioned reinforcement andFórmula:C15H23N5O2SPureza:99.92%Cor e Forma:SolidPeso molecular:337.44PF-0713
CAS:PF 0713, a GABAA receptor agonist, is used as an intravenous sedative-hypnotic for general anaesthesia, ICU sedation, procedural sedation, chemotherapy.Fórmula:C14H22OPureza:98%Cor e Forma:SolidPeso molecular:206.32Ro 41-3290
CAS:Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is an agonist of nonbenzodiazepine partial at the benzodiazepine receptor.Fórmula:C24H21ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:420.89SCH 50911
CAS:SCH 50911 is a selective GABA(B) receptor antagonist with IC50: 1.1 μM, boosting 3H overflow at IC50: 3 μM.Fórmula:C8H15NO3Pureza:98%Cor e Forma:SolidPeso molecular:173.21Anxiolytic/nonsedative agent-1
CAS:TCS 1205: Selective GABAA agonist, BzR affinity in bovine brain (Kis: 14-239 nM), α2 efficacy in vitro, anxioselective in vivo.Fórmula:C18H15N3O4Pureza:98.61%Cor e Forma:SolidPeso molecular:337.33Ref: TM-T23445
1mg64,00€2mg96,00€5mg115,00€10mg150,00€25mg330,00€50mg472,00€100mg655,00€500mg1.293,00€CP-409092 hydrochloride
CAS:CP-409092 hydrochloride is a partial agonist of the GABAA receptor with anti-anxiety activity.Fórmula:C17H20ClN3O2Cor e Forma:SolidPeso molecular:333.81Ciclotizolam
CAS:Ciclotizolam, a thienotriazolodiazepine derivative and partial GABAA receptor agonist, has low efficacy but similar affinity as brotizolam.Fórmula:C20H18BrClN4SCor e Forma:SolidPeso molecular:461.81Arbaclofen placarbil
CAS:Arbaclofen placarbil is a GABA(B) receptor agonist with better ADMET than R-baclofen, reducing postprandial reflux in GERD.Fórmula:C19H26ClNO6Cor e Forma:SolidPeso molecular:399.87SH-053-S-CH3-2'F
CAS:SH-053-S-CH3-2'F is a potent and selective agonist of GABAA receptors.Fórmula:C23H18FN3O2Cor e Forma:SolidPeso molecular:387.41
