Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 372 produtos de "Receptor GABA"
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Ethyl dirazepate
CAS:Ethyl dirazepate has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties,is a drug which is a benzodiazepine derivative.Fórmula:C18H14Cl2N2O3Pureza:98%Cor e Forma:SolidPeso molecular:377.22U-7524
CAS:U-7524 (AOAA), an inhibitor of GABA-T and other PLP-dependent enzymes, disrupts the Schiff base linkage, forming oxime complexes.Fórmula:C2H5NO3Cor e Forma:SolidPeso molecular:91.07Alfadolone
CAS:Alfadolone is an anesthetic derivative of pregnanedione.Fórmula:C21H32O4Cor e Forma:SolidPeso molecular:348.48Y 23684
CAS:Y-23684 is an anxiolytic drug with a novel chemical structure. It has similar effects to benzodiazepine drugs and is classed as a nonbenzodiazepine anxiolytic.Fórmula:C18H13ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:356.83Ro 22-8515
CAS:Ro 22-8515 is the ligand of benzodiazepine receptor.Fórmula:C18H12Cl2N2OCor e Forma:SolidPeso molecular:343.21Cyprodenate
CAS:Cyprodenate (Actebral) is a potent orally active brain-activating agent with appetite-suppressing properties, useful in studying metabolic.Fórmula:C13H25NO2Cor e Forma:SolidPeso molecular:227.34Ref: TM-T72977
1mg37,00€5mg72,00€10mg99,00€25mg169,00€50mg229,00€100mg320,00€200mg479,00€1mL*10mM (DMSO)79,00€ZK-91296
CAS:ZK-91296: GABA agonist, lowers anxiety without sedation, may target specific BZ receptor subtype.Fórmula:C23H22N2O4Pureza:98%Cor e Forma:SolidPeso molecular:390.43DS1
CAS:DS1 is a GABAA receptor agonist which can stimulate gonadotropin subunit gene expression in mouse.Fórmula:C18H10Br2ClN3OSCor e Forma:SolidPeso molecular:511.62SCH-50910 free base
CAS:SCH-50910 is an antagonist of GABAB receptor.Fórmula:C8H15NO3Cor e Forma:SolidPeso molecular:173.21Profadol hydrochloride
CAS:Profadol hydrochloride acts as a mixed agonist-antagonist of the μ-opioid receptor with analgesic activity.Fórmula:C14H22ClNOPureza:98%Cor e Forma:SolidPeso molecular:255.783-Methyl-GABA
CAS:3-Methyl-GABA activates GABA aminotransferase, fits GABAaR, stimulates GAD, and acts as an anticonvulsant.Fórmula:C20H30N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:522.59Ro15-4513
CAS:Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.Fórmula:C15H14N6O3Pureza:98%Cor e Forma:SolidPeso molecular:326.31Ro 14-7437
CAS:Ro 14-7437 is an antagonist of GABA-benzodiazepine receptor.Fórmula:C15H15N3O3Cor e Forma:SolidPeso molecular:285.3Adinazolam Mesylate
CAS:Adinazolam Mesylate is an anxiolytic and antidepressant agent. Adinazolam Mesylate binds to peripheral-type benzodiazepine receptors that interact allosterically with GABA receptors as an agonist to produce inhibitory effects.Fórmula:C20H22ClN5O3SPureza:98%Cor e Forma:SolidPeso molecular:447.94Ro 15-1310
CAS:Ro 15-3505, a benzodiazepine receptor partial inverse agonist, has shown the ability to improve impaired recent memory of aged mice.Fórmula:C15H14ClN3O3Cor e Forma:SolidPeso molecular:319.742-Hydroxysaclofen
CAS:2-Hydroxysaclofen is a GABAB receptor antagonist.Fórmula:C9H12ClNO4SPureza:98.56%Cor e Forma:White SolidPeso molecular:265.71CGS 20625
CAS:partial agonist for the benzodiazepine binding site of the GABAA receptorFórmula:C18H19N3O2Pureza:99.61%Cor e Forma:SolidPeso molecular:309.36SX-3228
CAS:SX-3228 is a selective agonist of benzodiazepine1 (BZ1) receptor(IC50 of 17 nM).Fórmula:C18H18N4O3Pureza:98%Cor e Forma:SolidPeso molecular:338.36CP-457920
CAS:CP-457920 is a selective α5 GABAA receptor inverse agonist that is suitable for investigating dementia in Alzheimer's disease.Fórmula:C18H17N3O3Pureza:99.06% - 99.74%Cor e Forma:SolidPeso molecular:323.35Org 20599
CAS:GABAA receptor agonistFórmula:C25H40ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:438.04U-101017
CAS:U-101017 is a partial benzodiazepine receptor and GABAA receptor agonist.Fórmula:C23H27ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:442.94TPA-023B
CAS:TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.Fórmula:C21H15F2N5OPureza:98%Cor e Forma:SolidPeso molecular:391.37CGP 7930
CAS:Positive allosteric modulator of GABAB receptorsFórmula:C19H32O2Pureza:98%Cor e Forma:SolidPeso molecular:292.46SCH 50911 hydrochloride
CAS:SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).Fórmula:C8H16ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:209.67BHF-177
CAS:BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.Fórmula:C19H20F3N3Cor e Forma:SolidPeso molecular:347.38CGS8216
CAS:CGS8216 shows analgesic activity at high doses, has anxiolytic activity, and can be used to study immune system disorders.Fórmula:C16H11N3OPureza:98.53%Cor e Forma:SolidPeso molecular:261.28DS2
CAS:Positive allosteric modulator of δ-subunit containing GABAA receptorsFórmula:C18H12ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:353.83(±)-Homoproline Hydrochloride
CAS:(±)-Homoproline Hydrochloride. Affordable Excellence: Reliable Quality You Can TrustFórmula:C6H12ClNO2Pureza:99.69%Cor e Forma:SolidPeso molecular:165.62MK-0343
CAS:MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.Fórmula:C19H17F2N7OPureza:98%Cor e Forma:SolidPeso molecular:397.3817-PA
CAS:17-PA is a GABAA receptor antagonist.Fórmula:C25H34OPureza:98%Cor e Forma:SolidPeso molecular:350.54Bifenazate
CAS:Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.Fórmula:C17H20N2O3Pureza:99.62%Cor e Forma:Solid CrystallinePeso molecular:300.35CGP11952
CAS:CGP11952 is same the benzodiazepines in its pharmacological action and it also is an experimental benzodiazepine derivative.Fórmula:C21H21Cl2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:446.33E2730
CAS:E2730 is a non-competitive GABA transporter 1 (GAT1) inhibitor with anti-epileptic activity, useful in studying neurological disorders.Fórmula:C9H8F4N2O2SPureza:98.22% - 98.54%Cor e Forma:SolidPeso molecular:284.23U-89843A
CAS:U-89843A is an allosteric modulator of the GABA_A receptor, known to enhance GABA-induced Cl^- currents [1].Fórmula:C16H24ClN5Pureza:98%Cor e Forma:SolidPeso molecular:321.85(R)-Baclofen hydrochloride
CAS:Arbaclofen HCl, a GABA-B agonist, treats spasticity from spinal injury by reducing excitatory transmission.Fórmula:C10H13Cl2NO2Pureza:98%Cor e Forma:SolidPeso molecular:250.12NO 711
CAS:NO 711（NNC-711 free acid） is a selective inhibitor of GAT-1, which enhances non-rapid eye movement sleep, and prevents paclitaxel-induced neuropathic pain.Fórmula:C21H22N2O3Pureza:99.70%Cor e Forma:SolidPeso molecular:350.41AZD 3043
CAS:AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.Fórmula:C19H29NO5Pureza:98.19% - 99.55%Cor e Forma:SolidPeso molecular:351.44mGAT3/4-IN-1
CAS:mGAT3/4-IN-1 inhibits mGAT3/4 with pIC50: 5.31/5.24, reduces neuropathic pain in diabetic mice.Fórmula:C26H31ClN2O2S2Cor e Forma:SolidPeso molecular:503.12GABAA receptor agent 4
CAS:Compound 1e is a potent γ-GABAAR antagonist with a Ki of 0.18 µM, offering immunomodulatory effects on T cell proliferation.Fórmula:C17H24N2OCor e Forma:SolidPeso molecular:272.39GABAA receptor agent 6
CAS:GABAA receptor agent 6 (compound 2027) is a potent γ-GABAAR antagonist with low cellular membrane permeability (Ki = 0.56 μM) [1].Fórmula:C18H25N3O2Cor e Forma:SolidPeso molecular:315.41TB 21007
CAS:GABAA receptor inverse agonistFórmula:C15H17NO2S3Pureza:98%Cor e Forma:SolidPeso molecular:339.5SL-651498
CAS:SL-651498, a GABAA receptor agonist, is used potentially for the treatment of anxiety.Fórmula:C23H20FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:389.42Bamaluzole
CAS:Bamaluzole is an agonist of GABA receptor.Fórmula:C14H12ClN3OPureza:98%Cor e Forma:SolidPeso molecular:273.72Ro 19-4603
CAS:Benzodiazepine inverse agonistFórmula:C15H17N3O3SPureza:98%Cor e Forma:SolidPeso molecular:319.38NAP-1
CAS:NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).Fórmula:C20H18ClNO2Cor e Forma:SolidPeso molecular:339.82GABAA receptor agent 7
CAS:Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.Fórmula:C18H13ClN4OCor e Forma:SolidPeso molecular:336.77MRK-623
CAS:MRK-623 (14k) is an oral GABA A agonist with high affinity for α1/α2/α3/α5 subunits and anxiolytic properties.Fórmula:C20H17FN4OCor e Forma:SolidPeso molecular:348.37Lesogaberan
CAS:Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).Fórmula:C3H9FNO2PPureza:98%Cor e Forma:SolidPeso molecular:141.08FG8119
CAS:FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.Fórmula:C17H15N5O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:321.33
