Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 336 produtos de "Receptor GABA"
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Bifenazate
CAS:<p>Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.</p>Fórmula:C17H20N2O3Pureza:99.62%Cor e Forma:Solid CrystallinePeso molecular:300.35E2730
CAS:<p>E2730 is a non-competitive GABA transporter 1 (GAT1) inhibitor with anti-epileptic activity, useful in studying neurological disorders.</p>Fórmula:C9H8F4N2O2SPureza:98.22% - 98.54%Cor e Forma:SolidPeso molecular:284.23U-89843A
CAS:<p>U-89843A is an allosteric modulator of the GABA_A receptor, known to enhance GABA-induced Cl^- currents [1].</p>Fórmula:C16H24ClN5Pureza:98%Cor e Forma:SolidPeso molecular:321.85(R)-Baclofen hydrochloride
CAS:<p>Arbaclofen HCl, a GABA-B agonist, treats spasticity from spinal injury by reducing excitatory transmission.</p>Fórmula:C10H13Cl2NO2Pureza:98%Cor e Forma:SolidPeso molecular:250.12Lesogaberan
CAS:<p>Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).</p>Fórmula:C3H9FNO2PPureza:98%Cor e Forma:SolidPeso molecular:141.08Tracazolate hydrochloride
CAS:<p>Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.</p>Fórmula:C16H25ClN4O2Pureza:99.52%Cor e Forma:SolidPeso molecular:340.85RO 4938581
CAS:<p>RO 4938581: potent GABAA α5 inverse agonist (Ki 4.6 nM); lower affinity for α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki: 174, 185, 80 nM).</p>Fórmula:C13H8BrF2N5Pureza:98%Cor e Forma:SolidPeso molecular:352.14AZD 3043
CAS:<p>AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.</p>Fórmula:C19H29NO5Pureza:98.19% - 99.55%Cor e Forma:SolidPeso molecular:351.44Phaclofen
CAS:<p>GABAB antagonist</p>Fórmula:C9H13ClNO3PPureza:99.32%Cor e Forma:White SolidPeso molecular:249.63Panadiplon
CAS:<p>Panadiplon (FG 10571) is a selective gamma-aminobutyric acid receptor agonist and partial agonist of 5GABAA, a benzodiazepine receptor, used in the treatment of</p>Fórmula:C18H17N5O2Pureza:98.30% - 98.94%Cor e Forma:SolidPeso molecular:335.36Cirsimaritin
CAS:<p>Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.</p>Fórmula:C17H14O6Pureza:99.9%Cor e Forma:SolidPeso molecular:314.29Progabide
CAS:<p>Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.</p>Fórmula:C17H16ClFN2O2Pureza:99.68%Cor e Forma:SolidPeso molecular:334.77Saripidem
CAS:<p>Saripidem (SL-85.0274) is a compound with anxiolytic activity.</p>Fórmula:C19H20ClN3OPureza:99.45%Cor e Forma:SolidPeso molecular:341.83NS-2710
CAS:<p>NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.</p>Fórmula:C22H20N4OPureza:99.7% - 99.82%Cor e Forma:SolidPeso molecular:356.42ELB-139
CAS:<p>ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.</p>Fórmula:C14H16ClN3OPureza:>99.99%Cor e Forma:SolidPeso molecular:277.75Ru-32514
CAS:<p>Ru-32514 is a benzodiazepine receptor agonist.</p>Fórmula:C18H17N3O2Pureza:99.21%Cor e Forma:SolidPeso molecular:307.35Fengabine
CAS:<p>Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.</p>Fórmula:C17H17Cl2NOPureza:99%Cor e Forma:SolidPeso molecular:322.23Nerisopam
CAS:<p>Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.</p>Fórmula:C18H19N3O2Pureza:97.07%Cor e Forma:SolidPeso molecular:309.36DMCM hydrochloride
CAS:<p>DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.</p>Fórmula:C17H19ClN2O4Pureza:99.56%Cor e Forma:SolidPeso molecular:350.8Suriclone
CAS:<p>Suriclone (RP 31264), a cyclic pyrrolidone for anxiety, modulates GABA-A receptors without major sedation.</p>Fórmula:C20H20ClN5O3S2Pureza:99.21% - 99.73%Cor e Forma:SolidPeso molecular:477.99NNC 05-711
CAS:<p>NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.</p>Fórmula:C21H23ClN2O3Pureza:99.92%Cor e Forma:SolidPeso molecular:386.87Riluzole hydrochloride
CAS:<p>Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).</p>Fórmula:C8H6ClF3N2OSPureza:99.76%Cor e Forma:SolidPeso molecular:270.66BPDBA
CAS:<p>BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and</p>Fórmula:C19H20Cl2N2OPureza:99.37% - 99.95%Cor e Forma:SolidPeso molecular:363.28RWJ-51204
CAS:<p>RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.</p>Fórmula:C21H19F2N3O3Pureza:99.57% - 99.95%Cor e Forma:SolidPeso molecular:399.39Lirequinil
CAS:<p>Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.</p>Fórmula:C26H25ClN2O3Pureza:98.54%Cor e Forma:SolidPeso molecular:448.94L-838417
CAS:<p>L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator used in the study of anxiety disorders</p>Fórmula:C19H19F2N7OPureza:98.12% - 99.70%Cor e Forma:SolidPeso molecular:399.4Divaplon
CAS:<p>Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.</p>Fórmula:C17H17N3O2Pureza:97.44% - 98.25%Cor e Forma:SolidPeso molecular:295.34Alpidem
CAS:<p>Alpidem (Ananxyl), a non-sedative imidazopyridine anxiolytic, treats anxiety with high benzodiazepine receptor affinity.</p>Fórmula:C21H23Cl2N3OPureza:99.56% - 99.97%Cor e Forma:White To Off-White SolidPeso molecular:404.33Sarmazenil
CAS:<p>Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor and is used in the study of chronic hepatic encephalopathy.</p>Fórmula:C15H14ClN3O3Pureza:99.46%Cor e Forma:SolidPeso molecular:319.74Golexanolone
CAS:<p>Golexanolone can be used to study neurological diseases.</p>Fórmula:C21H31NO2Pureza:99.90% - 99.99%Cor e Forma:SolidPeso molecular:329.48Muscimol HBr
CAS:<p>Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.</p>Fórmula:C4H7BrN2O2Pureza:98.13%Cor e Forma:Off-White PowderPeso molecular:195.01DSP-0565
CAS:<p>DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.</p>Fórmula:C14H12FNOPureza:99.51% - 99.56%Cor e Forma:SolidPeso molecular:229.25CGP 55845 hydrochloride
CAS:<p>CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].</p>Fórmula:C18H23Cl3NO3PCor e Forma:SolidPeso molecular:438.71FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Fórmula:C28H37FN2OPureza:99.86%Cor e Forma:SolidPeso molecular:436.6GMA-839
CAS:<p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>Fórmula:C21H31F3O3Pureza:98%Cor e Forma:SolidPeso molecular:388.46NO-711ME
CAS:<p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>Fórmula:C22H24N2O3Pureza:99.54%Cor e Forma:SolidPeso molecular:364.44U 89843A
CAS:<p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>Fórmula:C16H23N5Pureza:99.62%Cor e Forma:SolidPeso molecular:285.39(+)-Bicuculline methiodide
CAS:<p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>Fórmula:C21H20INO6Pureza:99.24%Cor e Forma:SolidPeso molecular:509.29CP-409092
CAS:<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Fórmula:C17H19N3O2Pureza:98%Cor e Forma:SolidPeso molecular:297.35mGAT3/4-IN-2
CAS:<p>mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.</p>Fórmula:C26H32ClN3OS2Cor e Forma:SolidPeso molecular:502.13COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Fórmula:C16H16ClNO3SPureza:99.75%Cor e Forma:SolidPeso molecular:337.82Diproqualone
CAS:<p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>Fórmula:C12H14N2O3Cor e Forma:SolidPeso molecular:234.255ADX71441
CAS:<p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.</p>Fórmula:C19H15ClF2N4O4Cor e Forma:SolidPeso molecular:436.8Adipiplon
CAS:<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Fórmula:C18H18FN7Cor e Forma:SolidPeso molecular:351.38PZ-II-029
CAS:<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Fórmula:C18H15N3O3Pureza:99.79%Cor e Forma:SolidPeso molecular:321.33CGP 64213
CAS:<p>CGP 64213 is a GABAb receptor agonist.</p>Fórmula:C26H36IN2O7PPureza:98%Cor e Forma:SolidPeso molecular:646.45(-)-Bicuculline methochloride
CAS:<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Fórmula:C21H20ClNO6Pureza:98%Cor e Forma:SolidPeso molecular:417.84GABAA receptor agent 2 TFA
CAS:<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Fórmula:C22H22F3N3O3Cor e Forma:SolidPeso molecular:433.42JM-1232
CAS:<p>JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.</p>Fórmula:C24H27N3O2Cor e Forma:SolidPeso molecular:389.49CGP-54626 free base
CAS:<p>CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).</p>Fórmula:C18H28Cl2NO3PPureza:98%Cor e Forma:SolidPeso molecular:408.3
