Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 367 produtos para "Receptor GABA".
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Imagabalin
CAS:Imagabalin is an active compound used in the study of neurological diseases.Fórmula:C9H19NO2Cor e Forma:SolidPeso molecular:173.25SCS
CAS:SCS is a GABAA receptor antagonist.Fórmula:C14H12N2O3Pureza:99.73%Cor e Forma:Yellow SolidPeso molecular:256.26PHP 501 trifluoroacetate
CAS:GABAA antagonistFórmula:C20H21N3OPureza:98%Cor e Forma:SolidPeso molecular:319.4GABA-IN-4
CAS:GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.Fórmula:C17H13ClN2O2Cor e Forma:SolidPeso molecular:312.75GABA receptor antagonist 2
CAS:GABA receptor antagonist 2 (Compound IId) is a GABA receptor blocker with an LC50 of 0.0735 μg/mL against Plutella xylostella (P. xylostella). This compound exhibits significant insecticidal activity against P. xylostella and its resistant strains, as well as against Spodoptera frugiperda and Chilo suppressalis. GABA receptor antagonist 2 can bind to the GABA receptor at the Drosophila RdlG335 site and is useful for managing resistant pest populations.Fórmula:C27H17BrF12N2O3Peso molecular:725.32EF1502 free base
CAS:EF1502 is a potent and selective GABA transporter inhibitor.Fórmula:C22H26N2O2S2Pureza:98%Cor e Forma:SolidPeso molecular:414.58Piperidine-4-sulfonic acid
CAS:Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].Fórmula:C5H11NO3SPureza:98%Cor e Forma:SolidPeso molecular:165.21Fletazepam
CAS:Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.Fórmula:C17H13ClF4N2Cor e Forma:SolidPeso molecular:356.74SGE-516
CAS:SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.Fórmula:C23H35N3O2Pureza:98%Cor e Forma:SolidPeso molecular:385.54Moxetomidate
CAS:Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.Fórmula:C15H18N2O3Cor e Forma:SolidPeso molecular:274.315Tuclazepam
CAS:Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.Fórmula:C17H16Cl2N2OCor e Forma:SolidPeso molecular:335.23GABAA receptor agonist 2
Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.Fórmula:C22H36O5Cor e Forma:SolidPeso molecular:380.52β-CCM
CAS:β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and convulsant effects. It enhances emotional reactivity and reduces interference sensitivity in spatial working memory tasks. β-CCM is applicable in research related to anxiety disorders.Fórmula:C13H10N2O2Cor e Forma:SolidPeso molecular:226.231CGS-9895
CAS:CGS-9895 is a GABA antagonist that operates by interacting with the benzodiazepine binding site on GABA receptors containing the γ subunit (ag).Fórmula:C17H13N3O2Cor e Forma:SolidPeso molecular:291.304S-8510 phosphate
CAS:S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).Fórmula:C12H13N4O6PPureza:98%Cor e Forma:SolidPeso molecular:340.23ZK 93426 hydrochloride
CAS:benzodiazepine receptor antagonist,competitiveFórmula:C18H21ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:348.82RPC425 free base
CAS:RPC425 is a noncompetitive inhibitors of the Betaine-γ-Aminobutyric Acid Transporter 1 (BGT1).Fórmula:C22H27NO2S2Pureza:98%Cor e Forma:SolidPeso molecular:401.595α-Androstan-3α-ol
CAS:5α-Androstan-3α-ol is a γ-aminobutyric acid (GABA) receptor agonist. It inhibits the transcriptional activity of the orphan nuclear receptor CAR (constitutive androstane receptor). By binding to CAR and promoting its dissociation from coactivator proteins, 5α-Androstan-3α-ol negatively regulates CAR's activity. This compound is useful for studying hormone metabolism and drug detoxification mechanisms mediated by nuclear receptors.Fórmula:C19H32OPeso molecular:276.46ADX71441
CAS:ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.Fórmula:C19H15ClF2N4O4Cor e Forma:SolidPeso molecular:436.8GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.45
