Transportador de monocarboxilato
Os transportadores de monocarboxilatos são proteínas de membrana que facilitam o transporte de monocarboxilatos, como lactato, piruvato e corpos cetônicos, através das membranas celulares. Esses transportadores desempenham um papel crucial nos processos metabólicos, particularmente em tecidos que dependem de lactato e outros monocarboxilatos como fontes de energia. Os MCTs também estão envolvidos na regulação do pH e são implicados em condições como câncer e distúrbios metabólicos. Na CymitQuimica, oferecemos uma variedade de moduladores de MCT para apoiar sua pesquisa em metabolismo, oncologia e energetics celular.
Foram encontrados 18 produtos para "Transportador de monocarboxilato".
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AR-C155858
CAS:AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).Fórmula:C21H27N5O5SPureza:98.96% - 99.42%Cor e Forma:SolidPeso molecular:461.535AZD0095
CAS:AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM.Fórmula:C27H32N8O2Pureza:98.51%Cor e Forma:SoildPeso molecular:500.5954AZ1422
AZ1422 is a selective MCT4 inhibitor, applicable for cancer research.Fórmula:C31H40N2O6Cor e Forma:SolidPeso molecular:536.28864AR-C141990 hydrochloride
CAS:AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.Fórmula:C26H29ClN4O4SCor e Forma:SolidPeso molecular:529.05Lactate transportor 1
Lactate Transporter 1 (Compound 1) serves as an active lactate transporter within living cells and exerts cytotoxic effects, exhibiting IC50 values of 3.36 μMPureza:98%Cor e Forma:Odour SolidMSC-4381
CAS:MSC-4381 (MCT4-IN-1) is an orally available and selectively modeled highly potent inhibitor of monocarboxylic acid transporter protein 4 (MCT4/SLC16A3) with potential anticancer and antitumor activity for the study of osteosarcoma.Fórmula:C26H20ClN3O6SPureza:99.04% - 99.55%Cor e Forma:SolidPeso molecular:537.972α-Cyano-4-hydroxycinnamic acid
CAS:α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvateFórmula:C10H7NO3Pureza:98.96% - 99.82%Cor e Forma:SolidPeso molecular:189.16757ACC2
CAS:7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.Fórmula:C18H15NO4Pureza:99.19% - ≥95%Cor e Forma:Yellow SolidPeso molecular:309.3167ACC1
CAS:7ACC1 (D 142) selectively affects a single part of the MCT symporter translocation cycle, leading to strict inhibition of lactate influx.Fórmula:C14H15NO4Pureza:99.90%Cor e Forma:SolidPeso molecular:261.2732BAY-8002
CAS:BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).Fórmula:C20H14ClNO5SPureza:98.7% - 99.13%Cor e Forma:SolidPeso molecular:415.847Syrosingopine
CAS:Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux.Cost-effective and quality-assured.Fórmula:C35H42N2O11Pureza:99.25% - 99.78%Cor e Forma:White SolidPeso molecular:666.7148AZD3965
CAS:AZD3965 (AZD-3965) is a selective inhibitor of monocarboxylate transporter 1 (MCT1).Fórmula:C21H24F3N5O5SPureza:98% - 99.90%Cor e Forma:White SolidPeso molecular:515.506VB124
CAS:VB124 is an orally active, potent and selective MCT4 inhibitor. VB124 blocked lactate importand expor in MDA-MB-231 cells.Cost-effective and quality-assured.Fórmula:C23H23ClN2O4Pureza:99.21% - 99.57%Cor e Forma:SoildPeso molecular:426.893MCT-IN-1
CAS:MCT-IN-1 (compound 2) acts as a potent inhibitor of the monocarboxylate transporter (MCT), demonstrating IC50 values of 9 nM for MCT1 and 14 nM for MCT4.Fórmula:C19H26N2O3Cor e Forma:SolidPeso molecular:330.42MCT1-IN-2
CAS:SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable.Fórmula:C25H29N3O2SCor e Forma:SolidPeso molecular:435.58AR-C117977
CAS:AR-C117977: Potent MCT1 inhibitor, reduces immune response, extends graft survival, induces tolerance in vitro/in vivo.Fórmula:C25H28N2O3S2Cor e Forma:SolidPeso molecular:468.63MCT1-IN-3
CAS:MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor.Fórmula:C22H19N3O4Pureza:98.93%Cor e Forma:SoildPeso molecular:389.404AR-C141990
CAS:AR-C141990 is a lactate transporters inhibitor.Fórmula:C26H28N4O4SCor e Forma:SolidPeso molecular:492.59
