Caseína quinase
As caseína quinases são uma família de proteínas quinases serina/treonina que regulam vários processos celulares, incluindo a reparação do DNA, os ritmos circadianos e a transdução de sinais. Essas quinases estão envolvidas na fosforilação de numerosas proteínas e estão implicadas em doenças como o câncer, distúrbios neurodegenerativos e síndromes metabólicas. Na CymitQuimica, oferecemos uma seleção de inibidores de caseína quinase para apoiar sua pesquisa em transdução de sinais, regulação do ciclo celular e desenvolvimento terapêutico.
Foram encontrados 130 produtos de "Caseína quinase"
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Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Fórmula:C16H16F3N5Pureza:99.97%Cor e Forma:SolidPeso molecular:335.33LH846
CAS:<p>LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2.</p>Fórmula:C16H13ClN2OSPureza:90% - 98.26%Cor e Forma:SolidPeso molecular:316.81NCC007
CAS:<p>NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.</p>Fórmula:C22H28F3N7Pureza:98.88%Cor e Forma:SolidPeso molecular:447.5MLN8054
CAS:<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Fórmula:C25H15ClF2N4O2Pureza:98.07% - 98.26%Cor e Forma:SolidPeso molecular:476.86Silmitasertib
CAS:<p>Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).</p>Fórmula:C19H12ClN3O2Pureza:98% - 99.90%Cor e Forma:SolidPeso molecular:349.77IC261
CAS:<p>IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.</p>Fórmula:C18H17NO4Pureza:99.45% - 99.91%Cor e Forma:SolidPeso molecular:311.33Umbralisib hydrochloride
CAS:<p>Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.</p>Fórmula:C31H25ClF3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:608.01SR-3029
CAS:<p>SR-3029 is a potent and highly specific CK1δ/CK1ε inhibitor.</p>Fórmula:C23H19F3N8OPureza:99.64%Cor e Forma:SolidPeso molecular:480.45TBB
CAS:<p>TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).</p>Fórmula:C6HBr4N3Pureza:98.51% - 99.45%Cor e Forma:Off-White SolidPeso molecular:434.71D4476
CAS:<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Fórmula:C23H18N4O3Pureza:99.7% - 99.96%Cor e Forma:SolidPeso molecular:398.41(E/Z)-GO289
CAS:<p>(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.</p>Fórmula:C17H15BrN4O2SPureza:98.1%Cor e Forma:SolidPeso molecular:419.3DMAT
CAS:<p>DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).</p>Fórmula:C9H7Br4N3Pureza:99.48%Cor e Forma:SolidPeso molecular:476.79AS-252424
CAS:<p>AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.</p>Fórmula:C14H8FNO4SPureza:99.06% - 99.09%Cor e Forma:SolidPeso molecular:305.28Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Fórmula:C31H24F3N5O3Pureza:99.56% - 99.56%Cor e Forma:White SolidPeso molecular:571.55TTP 22
CAS:<p>TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.</p>Fórmula:C16H14N2O2S2Pureza:97.08% - 97.78%Cor e Forma:SolidPeso molecular:330.42CKI-7
CAS:<p>CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Fórmula:C11H14Cl3N3O2SPureza:>99.99%Cor e Forma:SolidPeso molecular:358.67IWP-2
CAS:<p>IWP-2 is a Wnt pathway inhibitor and an ATP-competitive CK1δ inhibitor. IWP-2 inhibits self-renewal of embryonic stem cells. Cost effective and quality assured.</p>Fórmula:C22H18N4O2S3Pureza:96.1% - 99.49%Cor e Forma:SolidPeso molecular:466.6TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Fórmula:C24H21N3OSPureza:99.83%Cor e Forma:SolidPeso molecular:399.51Epiblastin A
CAS:Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.Fórmula:C12H10ClN7Pureza:99.45%Cor e Forma:SolidPeso molecular:287.71
