Receptor de Retinóide
Os receptores de retinoides são receptores nucleares que mediam os efeitos dos retinoides (derivados da vitamina A) na expressão gênica. Esses receptores desempenham um papel vital na diferenciação celular, proliferação e apoptose. Inibidores dos receptores de retinoides são utilizados para estudar seu envolvimento em várias doenças, incluindo câncer, distúrbios de pele e condições metabólicas. Ao modular a atividade dos receptores de retinoides, esses inibidores podem fornecer insights sobre os mecanismos de sinalização dos retinoides e seu potencial terapêutico. Na CymitQuimica, oferecemos inibidores dos receptores de retinoides para apoiar sua pesquisa em dermatologia, oncologia e regulação metabólica.
Foram encontrados 26 produtos de "Receptor de Retinóide"
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LG-100064
CAS:LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Fórmula:C23H26O3Pureza:98.65%Cor e Forma:SolidPeso molecular:350.45Ref: TM-T11844
2mg47,00€5mg70,00€10mg97,00€25mg167,00€50mg249,00€100mg369,00€200mg545,00€1mL*10mM (DMSO)77,00€BMS 195614
CAS:BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.Fórmula:C29H24N2O3Pureza:97.14%Cor e Forma:SolidPeso molecular:448.51CD3254
CAS:CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.Fórmula:C24H28O3Pureza:98.71% - 98.71%Cor e Forma:SolidPeso molecular:364.48CD437
CAS:CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.Fórmula:C27H26O3Pureza:98.92% - 99.63%Cor e Forma:SolidPeso molecular:398.49Tazarotene
CAS:Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.Fórmula:C21H21NO2SPureza:97.01% - 99.14%Cor e Forma:White SolidPeso molecular:351.46Ref: TM-T6696
5mg38,00€10mg49,00€25mg88,00€50mg147,00€100mg256,00€200mg334,00€500mg563,00€1mL*10mM (DMSO)55,00€Fenretinide
CAS:Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Fórmula:C26H33NO2Pureza:98% - 99.68%Cor e Forma:Yellow PowderPeso molecular:391.55UVI 3003
CAS:UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Fórmula:C28H36O4Pureza:99.82%Cor e Forma:SolidPeso molecular:436.58Ref: TM-T17209
1mg35,00€2mg52,00€5mg74,00€10mg119,00€25mg243,00€50mg406,00€100mg607,00€1mL*10mM (DMSO)86,00€AR7
CAS:AR7 is a retinoic acid receptor α (RARα) antagonist.Fórmula:C15H12ClNOPureza:98.12% - 99.86%Cor e Forma:SolidPeso molecular:257.71Ref: TM-T3955
1mg37,00€5mg69,00€10mg96,00€25mg202,00€50mg329,00€100mg550,00€200mg758,00€500mg1.159,00€1mL*10mM (DMSO)74,00€palovarotene
CAS:<p>Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).</p>Fórmula:C27H30N2O2Pureza:97.88% - 98.05%Cor e Forma:SolidPeso molecular:414.54trifarotene
CAS:<p>Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.</p>Fórmula:C29H33NO4Pureza:99.51%Cor e Forma:SolidPeso molecular:459.58Bexarotene
CAS:Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).Fórmula:C24H28O2Pureza:99% - 99.65%Cor e Forma:White SolidPeso molecular:348.48BMS270394
CAS:BMS270394 is a RARγ agonist used in the study of breast cancer and skin diseases.Fórmula:C23H26FNO4Cor e Forma:SolidPeso molecular:399.46CD2665
CAS:CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.Fórmula:C31H34O5Pureza:99.71%Cor e Forma:SolidPeso molecular:486.6MM 11253
CAS:MM 11253 is a RARγ antagonist with IC50 of 44nM.Fórmula:C28H30O2S2Pureza:99.41%Cor e Forma:SolidPeso molecular:462.67Ch55
CAS:Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.Fórmula:C24H28O3Pureza:99.55%Cor e Forma:SolidPeso molecular:364.48Ref: TM-T14946
1mg42,00€5mg87,00€10mg124,00€25mg254,00€50mg394,00€100mg612,00€200mg842,00€1mL*10mM (DMSO)94,00€Fluorobexarotene
CAS:Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 nM and EC50 of 43 nM for RXRα.Fórmula:C24H27FO2Pureza:99.08%Cor e Forma:SolidPeso molecular:366.47Ref: TM-T11303
1mg170,00€5mg416,00€10mg615,00€25mg964,00€50mg1.305,00€100mg1.755,00€500mg3.501,00€1mL*10mM (DMSO)335,00€BMS 753
CAS:<p>BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).</p>Fórmula:C21H21NO4Pureza:98.55%Cor e Forma:SolidPeso molecular:351.4AGN 196996
CAS:AGN 196996: strong RARα inhibitor (Ki: 2 nM), weak for RARβ/γ (Ki: 1087/8523 nM).Fórmula:C24H20BrNO5Pureza:99.94%Cor e Forma:SolidPeso molecular:482.32Ref: TM-T10261
1mg59,00€5mg131,00€10mg190,00€25mg329,00€50mg477,00€100mg702,00€1mL*10mM (DMSO)138,00€AC-261066
CAS:AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.Fórmula:C17H20FNO4SPureza:99.64%Cor e Forma:SolidPeso molecular:353.41KCL-286
CAS:KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).Fórmula:C19H14N2O4Pureza:99.93%Cor e Forma:SolidPeso molecular:334.33
