
Lipase
As lipases são enzimas que catalisam a hidrólise de triglicerídeos em ácidos graxos livres e glicerol, desempenhando um papel crucial na digestão, absorção e metabolismo dos lipídios. Inibidores de lipase são de interesse no tratamento da obesidade, pancreatite e distúrbios metabólicos relacionados aos lipídios. Na CymitQuimica, oferecemos uma variedade de inibidores de lipase para apoiar sua pesquisa em metabolismo, obesidade e saúde gastrointestinal.
Foram encontrados 78 produtos para "Lipase".
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Hi 76-0079
CAS:Hi 76-0079: HSL inhibitor, IC50=184 nM; potential for obesity and diabetes research.Fórmula:C11H13ClN2O3Pureza:99.9%Cor e Forma:SolidPeso molecular:256.69JZP-430
CAS:JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM).Fórmula:C16H26N4O3SPureza:99.78%Cor e Forma:SolidPeso molecular:354.468JW 642
CAS:JW 642 inhibits MAGL in mouse, rat, human brains (IC50: 7.6, 14, 3.7 nM).Fórmula:C21H20F6N2O3Pureza:99.28%Cor e Forma:SolidPeso molecular:462.39DDAO
CAS:DDAO: NIR red fluorescent probe, λem 656 nm, excitation 600-650 nm, detects various enzymes.Fórmula:C15H11Cl2NO2Pureza:>99.99%Cor e Forma:SolidPeso molecular:308.159LP-922056
CAS:LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.Fórmula:C11H9ClN2O2S2Pureza:99.84%Cor e Forma:White SolidPeso molecular:300.784hPL-IN-1
CAS:hPL-IN-1 is a potent reversible pancreatic lipase (PL) inhibitor (IC50=1.86 μM) that can be used to study obesity-related diseases.Fórmula:C19H11Cl2F2NO3Pureza:98.41%Cor e Forma:SoildPeso molecular:410.2Lipase Substrate
CAS:Lipase Substrate is a substrate of lipase to detect activity.Fórmula:C45H69NO8Cor e Forma:SolidPeso molecular:752.046Pancreatic lipase-IN-1
Pancreatic lipase-IN-1 (compound 8) is an inhibitor of pancreatic lipase with a Ki value of 1.288 μM.Fórmula:C35H50O6Peso molecular:566.36074hPL-IN-2
CAS:hPL-IN-2 is a potent, reversible and non-competitive inhibitor of Pancreatic lipase (IC50: 1.63 μM) that can be used to investigate obesity-related diseases.Fórmula:C19H11Cl4NO3Pureza:97.31%Cor e Forma:SoildPeso molecular:443.111,2-Dioleoyl-3-behenoylglycerol
CAS:1,2-Dioleoyl-3-behenoylglycerol (BOO) decreases pancreatic lipase activity and hinders the accumulation of visceral fat as well as hepatic triacylglycerol (TAG) [1].Fórmula:C61H114O6Peso molecular:943.55Lipstatin
CAS:Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases.Fórmula:C29H49NO5Pureza:98%Cor e Forma:SolidPeso molecular:491.7Lalistat 2
CAS:Lalistat 2: selective lysosomal acid lipase inhibitor, IC50 152 nM, no effect on pancreatic/milk lipase <10 μM.Fórmula:C13H20N4O2SPureza:99.84%Cor e Forma:SolidPeso molecular:296.388URB754
CAS:"URB754 inhibits rat MAGL with an IC50 of 200 nM, possibly due to impurity. Weak FAAH and CB1 binding, no COX inhibition. Potential pain management target."Fórmula:C16H14N2O2Cor e Forma:SolidPeso molecular:266.2946Pancreatic lipase-IN-2
Pancreatic lipase-IN-2 (compound 7r) is a potent inhibitor of pancreatic lipase (PL), with an IC50 value of 2.67 μM, and exhibits anti-obesity effects.Fórmula:C32H33N3O2SCor e Forma:SolidPeso molecular:523.22935Lipase, triacylglycerol
CAS:Lipase, triacylglycerol (Alkaline lipase) is a specific enzyme catabolism of triacylglycerol to glycerol and fatty acids,transfer to various tissues.Fórmula:C11H9N3NaO2Cor e Forma:SolidPeso molecular:238.201MEDI-5884
CAS:MEDI-5884 is a humanized IgG4Pκ neutralizing monoclonal antibody that targets endothelial lipase (EL). By inhibiting EL, MEDI-5884 leads to an increase in high-density lipoprotein (HDL) levels, particularly phosphatidylinositol and cholesterol ester, thereby enhancing its functionality. This compound is applicable in research related to cardiovascular diseases, such as coronary artery disease (CAD).Cetilistat
CAS:Cetilistat (ATL-962) is a drug for obesity and type 2 diabetes, blocking pancreatic lipase. Developed by Alizyme.Fórmula:C25H39NO3Pureza:97.12% - 97.47%Cor e Forma:White SolidPeso molecular:401.58Ibrolipim
CAS:Ibrolipim (NO-1886) attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.Fórmula:C19H20BrN2O4PPureza:98.04%Cor e Forma:SolidPeso molecular:451.251MAGL-IN-4
CAS:MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.Fórmula:C18H21ClN2O4Pureza:99.79%Cor e Forma:SolidPeso molecular:364.823RHC 80267
CAS:RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)Fórmula:C20H34N4O4Pureza:99.54%Cor e Forma:White SolidPeso molecular:394.51

