Anidrase carbónica
A anidrase carbônica é uma enzima que catalisa a conversão reversível de dióxido de carbono e água em bicarbonato e prótons. Esta enzima desempenha um papel crucial na manutenção do equilíbrio ácido-base, respiração e transporte de dióxido de carbono no sangue. Inibidores da anidrase carbônica são usados no tratamento de glaucoma, epilepsia e mal da altitude, bem como em pesquisas sobre homeostase ácido-base e troca gasosa. Na CymitQuimica, oferecemos uma gama de inibidores e reagentes de anidrase carbônica de alta qualidade para apoiar sua pesquisa em enzimologia, fisiologia respiratória e desenvolvimento terapêutico.
Foram encontrados 197 produtos de "Anidrase carbónica"
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(E)-Dehydrodiconiferyl alcohol
CAS:(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.Fórmula:C20H22O6Cor e Forma:SolidPeso molecular:358.39CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Cor e Forma:Odour SolidDPP IV/hCA II-IN-1
CAS:DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).Fórmula:C17H20N2O5SCor e Forma:SolidPeso molecular:364.42CAIX Inhibitor S4
CAS:CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.Fórmula:C15H17N3O4SPureza:99.07%Cor e Forma:SolidPeso molecular:335.38Ref: TM-T36758
2mg38,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg90,00€25mg178,00€50mg334,00€100mg500,00€500mg1.099,00€hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Fórmula:C20H25N3O4SCor e Forma:SolidPeso molecular:403.5hCAIX-IN-17
hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.Fórmula:C19H18N2O3SCor e Forma:SolidPeso molecular:354.422-Methoxy-4-propylphenol
CAS:2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.
Fórmula:C10H14O2Cor e Forma:SolidPeso molecular:166.225,6-Dihydro-2H-pyran-2-one
CAS:5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.Fórmula:C5H6O2Cor e Forma:SolidPeso molecular:98.1Carbonic anhydrase inhibitor 30
Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].Fórmula:C23H22FN3O5SCor e Forma:SolidPeso molecular:471.12642Chlorothiazide
CAS:Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Cor e Forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.72Dorzolamide
CAS:Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.
Fórmula:C10H16N2O4S3Pureza:98%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:324.44hCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Fórmula:C24H17Cl2N3O3S2Cor e Forma:SolidPeso molecular:530.446CAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Fórmula:C23H21N5O3SCor e Forma:SolidPeso molecular:447.51hCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.Fórmula:C24H28N6O6SPureza:98%Cor e Forma:SolidPeso molecular:528.58Pyrocatechol
CAS:Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.Fórmula:C6H6O2Pureza:99.96%Cor e Forma:SolidPeso molecular:110.11hCAIX/XII-IN-14
hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.Fórmula:C16H14F3N3O4SCor e Forma:SolidPeso molecular:401.36Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Fórmula:C17H16N6O3SCor e Forma:SolidPeso molecular:384.41hCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII andFórmula:C23H26N6O5SPureza:98%Cor e Forma:SolidPeso molecular:498.55α-Pyrone
CAS:Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9Fórmula:C5H4O2Cor e Forma:SolidPeso molecular:96.08hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Cor e Forma:Odour Solid
