Tansportador
As proteínas transportadoras estão envolvidas no movimento de moléculas através das membranas celulares, desempenhando papéis vitais na captação de nutrientes, eliminação de resíduos e resistência a medicamentos. Inibidores de proteínas transportadoras são usados para estudar a função dessas proteínas em vários processos fisiológicos e patológicos, incluindo distúrbios metabólicos, câncer e liberação de medicamentos. Ao modular a atividade dos transportadores, os pesquisadores podem obter insights sobre os mecanismos de transporte celular e desenvolver novas estratégias terapêuticas. Na CymitQuimica, oferecemos uma gama de inibidores de transportadores para apoiar sua pesquisa em farmacologia, biologia celular e regulação metabólica.
Foram encontrados 46 produtos de "Tansportador"
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EAAT2 activator 1
CAS:EAAT2 activator 1 (3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine) is a thiopyridazine derivative that has been found to increase EAAT2 proteinFórmula:C16H11ClFN3SPureza:98.86%Cor e Forma:SolidPeso molecular:331.8BPTES
CAS:<p>BPTES(IC50 of 0.16 μM) is an effective and specific GlutamiN/Ase GLS1 (KGA) inhibitor.</p>Fórmula:C24H24N6O2S3Pureza:95.83% - 99.64%Cor e Forma:SolidPeso molecular:524.68STF-31
CAS:STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.Fórmula:C23H25N3O3SPureza:99.55% - >99.99%Cor e Forma:SolidPeso molecular:423.53Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Fórmula:C23H26FN5O3Pureza:97.35%Cor e Forma:SolidPeso molecular:439.48Clodronate disodium tetrahydrate
CAS:<p>Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.</p>Fórmula:CH10Cl2Na2O10P2Pureza:98%Cor e Forma:SolidPeso molecular:360.92Nefazodone hydrochloride
CAS:<p>Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.</p>Fórmula:C25H33Cl2N5O2Pureza:99% - 99.86%Cor e Forma:White SolidPeso molecular:506.47KL-11743
CAS:KL-11743 blocks glucose metabolism, collapses NADH, and increases aspartate, shifting cells to oxidative phosphorylation.Fórmula:C30H30N6O3Pureza:98.46% - 99.57%Cor e Forma:SolidPeso molecular:522.6AHN 1-055 hydrochloride
CAS:AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).Fórmula:C21H24ClF2NOPureza:99.89%Cor e Forma:SolidPeso molecular:379.87Tormentic acid
CAS:Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties,Fórmula:C30H48O5Pureza:97.02% - 99.86%Cor e Forma:SolidPeso molecular:488.7Indican
CAS:Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.Fórmula:C14H17NO6Pureza:99.78% - 99.92%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:295.29BAY-876
CAS:BAY-876 is a selective and orally GLUT1 inhibitor. BAY-876 inhibits glycolytic metabolism and exhibits antitumor activity. Cost-effective and quality-assured.Fórmula:C24H16F4N6O2Pureza:98.61% - 99.78%Cor e Forma:SolidPeso molecular:496.42Dotinurad
CAS:Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).Fórmula:C14H9Cl2NO4SPureza:97.43% - 98.04%Cor e Forma:SolidPeso molecular:358.2CTPI-2
CAS:CTPI-2 inhibits SLC25A1 (KD: 3.5 μM), glycolysis, PPARγ, GLUT4, has anti-tumor effects, and combats NASH and diet-induced obesity.Fórmula:C13H9ClN2O6SPureza:97.23%Cor e Forma:SolidPeso molecular:356.74Valbenazine
CAS:Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.Fórmula:C24H38N2O4Pureza:97.58%Cor e Forma:SolidPeso molecular:418.57α-Cyano-4-hydroxycinnamic acid
CAS:α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvateFórmula:C10H7NO3Pureza:99.8% - 99.86%Cor e Forma:PowderPeso molecular:189.17TCID
CAS:<p>TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.</p>Fórmula:C9H2Cl4O2Pureza:99.34%Cor e Forma:SolidPeso molecular:283.92L-Arginine
CAS:<p>L-Arginine (L-Arg) is a substrate of endothelial nitric oxide synthase (eNOS). High-Quality, Low-Cost!</p>Fórmula:C6H14N4O2Pureza:99.7% - 99.98%Cor e Forma:Solid CrystallinePeso molecular:174.2WZB117
CAS:WZB117 inhibits GLUT1; IC50 ~10μM slows A549 lung & MCF7 breast cancer cell growth.Fórmula:C20H13FO6Pureza:99.03% - 99.18%Cor e Forma:SolidPeso molecular:368.31DA-023
CAS:DA-023 (Compound 4) acts as a selective positive allosteric modulator (PAM) of EAAT2, exhibiting an EC 50 value of 1 nM [1].Fórmula:C20H25N7Peso molecular:363.46GT 949
CAS:GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) (EC50: 0.26 nM).Fórmula:C30H37N7O2Pureza:99.95%Cor e Forma:SolidPeso molecular:527.66
