FAAH
A Hidrolase de Amida de Ácido Graxo (FAAH) é uma enzima que degrada amidas de ácidos graxos, incluindo endocanabinoides como a anandamida. Esses compostos estão envolvidos na regulação da dor, humor, apetite e memória. A inibição da FAAH pode aumentar os níveis dessas moléculas de sinalização, oferecendo potenciais benefícios terapêuticos para dor, ansiedade e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de inibidores de FAAH para apoiar sua pesquisa em neurociência, manejo da dor e sinalização endocanabinoide.
Foram encontrados 63 produtos de "FAAH"
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JZL195
CAS:<p>JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.</p>Fórmula:C24H23N3O5Pureza:99.81%Cor e Forma:SolidPeso molecular:433.46Biochanin A
CAS:<p>Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.</p>Fórmula:C16H12O5Pureza:97.1% - 98.97%Cor e Forma:SolidPeso molecular:284.26N-Benzyllinolenamide
CAS:<p>N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).</p>Fórmula:C25H37NOPureza:98.7% - 99.92%Cor e Forma:SolidPeso molecular:367.57PF-04457845
CAS:<p>PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).</p>Fórmula:C23H20F3N5O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:455.43N-Benzylpalmitamide
CAS:<p>N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the</p>Fórmula:C23H39NOPureza:97.08% - 99.77%Cor e Forma:SolidPeso molecular:345.56WWL 154
CAS:<p>WWL 154 is an serine hydrolase (SH) and fatty acid amide hydrolase FAAH-4 inhibitor.</p>Fórmula:C18H19N3O5Pureza:99.22%Cor e Forma:SolidPeso molecular:357.36MAGL-IN-4
CAS:<p>MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.</p>Fórmula:C18H21ClN2O4Pureza:99.79%Cor e Forma:SolidPeso molecular:364.82FAAH-IN-8
CAS:<p>FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 of 6.7 nM and a Ki of 5 nM. It exhibits high blood-brain permeability and a significant antioxidant profile without neurotoxicity [1].</p>Fórmula:C18H14N4OCor e Forma:SolidPeso molecular:302.33AKU-005
CAS:<p>AKU-005 is a dual inhibitor of FAAH and MAGL, exhibiting IC50 values of 63 nM and 389 nM against rat and human FAAH, respectively. This compound has potential for researching trigeminal nociceptive hypersensitivity.</p>Fórmula:C20H21N5OCor e Forma:SolidPeso molecular:347.41URB532
CAS:<p>URB532 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor.</p>Fórmula:C18H21NO3Pureza:98%Cor e Forma:SolidPeso molecular:299.36SA57
CAS:<p>SA57 is a potent, selective inhibitor of FAAH(IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH).</p>Fórmula:C17H23ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:338.83Acetylhydrolase-IN-1
CAS:<p>Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).</p>Fórmula:C23H48NO7PPureza:98%Cor e Forma:SolidPeso molecular:481.6OL-135
CAS:<p>OL-135: CNS-accessible, potent, selective FAAH inhibitor with analgesic effects in animals, no motor impairment.</p>Fórmula:C21H22N2O2Cor e Forma:SolidPeso molecular:334.41FAAH-IN-7
<p>FAAH-IN-7: Reversible FAAH inhibitor, IC50=8.29 nM, reduces oxidative stress, neuroprotective in neuroinflammation.</p>Fórmula:C26H29N3O4Cor e Forma:SolidPeso molecular:447.53FAAH-IN-5
CAS:<p>FAAH-IN-5 (Compound 7) selectively, irreversibly inhibits FAAH (IC50: 10.5 nM) with low PAMPA permeability.</p>Fórmula:C21H19N3O6SCor e Forma:SolidPeso molecular:441.46URB-694
CAS:<p>URB-694 is a fatty acid amide hydrolase (FAAH) inhibitor.</p>Fórmula:C19H21NO3Cor e Forma:SolidPeso molecular:311.37MDPD
CAS:<p>MDPD boosts AtFAAH, the enzyme degrading NAEs in Arabidopsis, reducing NAE 12:0's growth inhibition.</p>Fórmula:C21H19N3O3Cor e Forma:SolidPeso molecular:361.39TAK 21d
CAS:<p>Potent FAAH inhibitor</p>Fórmula:C19H17F2N7OPureza:98%Cor e Forma:SolidPeso molecular:397.38Arachidonyl serotonin
CAS:<p>Dual FAAH inhibitor/TRPV1 antagonist</p>Fórmula:C30H42N2O2Pureza:98%Cor e Forma:SolidPeso molecular:462.67FAAH inhibitor 1
CAS:<p>FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.</p>Fórmula:C24H23N3O3S3Pureza:99.6%Cor e Forma:SolidPeso molecular:497.65
