FAAH
A Hidrolase de Amida de Ácido Graxo (FAAH) é uma enzima que degrada amidas de ácidos graxos, incluindo endocanabinoides como a anandamida. Esses compostos estão envolvidos na regulação da dor, humor, apetite e memória. A inibição da FAAH pode aumentar os níveis dessas moléculas de sinalização, oferecendo potenciais benefícios terapêuticos para dor, ansiedade e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de inibidores de FAAH para apoiar sua pesquisa em neurociência, manejo da dor e sinalização endocanabinoide.
Foram encontrados 62 produtos para "FAAH".
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PF-04457845
CAS:PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Fórmula:C23H20F3N5O2Pureza:99.93%Cor e Forma:SolidPeso molecular:455.43Ref: TM-T4323
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg84,00€25mg155,00€50mg222,00€100mg396,00€200mg515,00€Biochanin A
CAS:Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Fórmula:C16H12O5Pureza:97.59% - 98.97%Cor e Forma:SolidPeso molecular:284.26JNJ-42165279
CAS:JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.Fórmula:C18H17ClF2N4O3Pureza:99.88% - 99.95%Cor e Forma:SolidPeso molecular:410.8Ref: TM-T3215
2mg43,00€5mg62,00€1mL*10mM (DMSO)72,00€10mg92,00€25mg161,00€50mg234,00€100mg344,00€200mg485,00€4-Nonylphenylboronic acid
CAS:4-Nonylphenylboronic acid is a inhibitor of FAAH.Fórmula:C15H25BO2Pureza:97.63%Cor e Forma:SolidPeso molecular:248.17N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Fórmula:C25H37NOPureza:98.7% - 99.92%Cor e Forma:SolidPeso molecular:367.57Ref: TM-TN1965
1mg81,00€5mg170,00€1mL*10mM (DMSO)177,00€10mg260,00€25mg440,00€50mg628,00€100mg872,00€200mg1.153,00€AA38-3
CAS:AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH)Fórmula:C12H14N2O4Pureza:99.56%Cor e Forma:SolidPeso molecular:250.25FAAH inhibitor 2
CAS:FAAH Inhibitor 2 (Compound 17b) is an irreversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrating an IC50 value of 0.153 μM [1].Fórmula:C24H40N2O2Cor e Forma:SolidPeso molecular:388.59FAAH-IN-8
CAS:FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 of 6.7 nM and a Ki of 5 nM. It exhibits high blood-brain permeability and a significant antioxidant profile without neurotoxicity [1].Fórmula:C18H14N4OCor e Forma:SolidPeso molecular:302.33AKU-005
CAS:AKU-005 is a dual inhibitor of FAAH and MAGL, exhibiting IC50 values of 63 nM and 389 nM against rat and human FAAH, respectively. This compound has potential for researching trigeminal nociceptive hypersensitivity.Fórmula:C20H21N5OCor e Forma:SolidPeso molecular:347.41JNJ-40413269
CAS:JNJ-40413269 inhibits FAAH, engages central targets, and is effective in rat neuropathic pain.Fórmula:C19H15ClF3N3OCor e Forma:SolidPeso molecular:393.79Arachidonyl serotonin
CAS:Dual FAAH inhibitor/TRPV1 antagonistFórmula:C30H42N2O2Pureza:98%Cor e Forma:SolidPeso molecular:462.67URB532
CAS:URB532 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor.Fórmula:C18H21NO3Pureza:98%Cor e Forma:SolidPeso molecular:299.36JNJ-42165279 dihydrochloride
CAS:JNJ-42165279 (dihydrochloride) is an FAAH inhibitor with IC50 values of 70 nM for hFAAH and 313 nM for rFAAH, respectively [1].Fórmula:C18H19Cl3F2N4O3Cor e Forma:SolidPeso molecular:483.72VDM 11
CAS:anandamide transport inhibitorFórmula:C27H39NO2Pureza:98%Cor e Forma:SolidPeso molecular:409.6MK-4409
CAS:MK-4409, a potent and selective fatty acid amide hydrolase (FAAH) inhibitor, is being investigated for the treatment of inflammatory and neuropathic pain.Fórmula:C22H17ClFN3O2SPureza:99.80% - 99.87%Cor e Forma:White SolidPeso molecular:441.91FAAH inhibitor 1
CAS:FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Fórmula:C24H23N3O3S3Pureza:99.6%Cor e Forma:Yellow SolidPeso molecular:497.65Ref: TM-T11256
1mg38,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg124,00€25mg203,00€50mg294,00€100mg411,00€200mg553,00€OL-135
CAS:OL-135: CNS-accessible, potent, selective FAAH inhibitor with analgesic effects in animals, no motor impairment.Fórmula:C21H22N2O2Cor e Forma:SolidPeso molecular:334.41Acetylhydrolase-IN-1
CAS:Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).Fórmula:C23H48NO7PPureza:98%Cor e Forma:SolidPeso molecular:481.6SA57
CAS:SA57 is a potent, selective inhibitor of FAAH(IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH).Fórmula:C17H23ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:338.83
