FAAH
A Hidrolase de Amida de Ácido Graxo (FAAH) é uma enzima que degrada amidas de ácidos graxos, incluindo endocanabinoides como a anandamida. Esses compostos estão envolvidos na regulação da dor, humor, apetite e memória. A inibição da FAAH pode aumentar os níveis dessas moléculas de sinalização, oferecendo potenciais benefícios terapêuticos para dor, ansiedade e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de inibidores de FAAH para apoiar sua pesquisa em neurociência, manejo da dor e sinalização endocanabinoide.
Foram encontrados 63 produtos para "FAAH".
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N-Benzylpalmitamide
CAS:N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for theFórmula:C23H39NOPureza:97.08% - 99.77%Cor e Forma:SolidPeso molecular:345.56Biochanin A
CAS:Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Fórmula:C16H12O5Pureza:97.59% - 98.97%Cor e Forma:Yellow SolidPeso molecular:284.26JNJ-42165279
CAS:JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.Fórmula:C18H17ClF2N4O3Pureza:99.88% - 99.95%Cor e Forma:SolidPeso molecular:410.8Ref: TM-T3215
2mg43,00€5mg62,00€1mL*10mM (DMSO)72,00€10mg92,00€25mg161,00€50mg234,00€100mg344,00€200mg485,00€4-Nonylphenylboronic acid
CAS:4-Nonylphenylboronic acid is a inhibitor of FAAH.Fórmula:C15H25BO2Pureza:97.63%Cor e Forma:SolidPeso molecular:248.17URB-597
CAS:URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Fórmula:C20H22N2O3Pureza:97.20% - 98.24%Cor e Forma:White SolidPeso molecular:338.4N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Fórmula:C25H37NOPureza:98.7% - 99.92%Cor e Forma:SolidPeso molecular:367.57Ref: TM-TN1965
1mg81,00€5mg170,00€1mL*10mM (DMSO)177,00€10mg260,00€25mg440,00€50mg628,00€100mg872,00€200mg1.153,00€AA38-3
CAS:AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH)Fórmula:C12H14N2O4Pureza:99.56%Cor e Forma:SolidPeso molecular:250.25FAAH inhibitor 2
CAS:FAAH Inhibitor 2 (Compound 17b) is an irreversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrating an IC50 value of 0.153 μM [1].Fórmula:C24H40N2O2Cor e Forma:SolidPeso molecular:388.59AKU-005
CAS:AKU-005 is a dual inhibitor of FAAH and MAGL, exhibiting IC50 values of 63 nM and 389 nM against rat and human FAAH, respectively. This compound has potential for researching trigeminal nociceptive hypersensitivity.Fórmula:C20H21N5OCor e Forma:SolidPeso molecular:347.41FAAH-IN-8
CAS:FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 of 6.7 nM and a Ki of 5 nM. It exhibits high blood-brain permeability and a significant antioxidant profile without neurotoxicity [1].Fórmula:C18H14N4OCor e Forma:SolidPeso molecular:302.33FAAH-IN-5
CAS:FAAH-IN-5 (Compound 7) selectively, irreversibly inhibits FAAH (IC50: 10.5 nM) with low PAMPA permeability.Fórmula:C21H19N3O6SCor e Forma:SolidPeso molecular:441.46URB-694
CAS:URB-694 is a fatty acid amide hydrolase (FAAH) inhibitor.Fórmula:C19H21NO3Cor e Forma:SolidPeso molecular:311.37MDPD
CAS:MDPD boosts AtFAAH, the enzyme degrading NAEs in Arabidopsis, reducing NAE 12:0's growth inhibition.Fórmula:C21H19N3O3Cor e Forma:SolidPeso molecular:361.39Acetylhydrolase-IN-1
CAS:Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).Fórmula:C23H48NO7PPureza:98%Cor e Forma:SolidPeso molecular:481.6JNJ-40413269
CAS:JNJ-40413269 inhibits FAAH, engages central targets, and is effective in rat neuropathic pain.Fórmula:C19H15ClF3N3OCor e Forma:SolidPeso molecular:393.79FAAH-IN-7
FAAH-IN-7: Reversible FAAH inhibitor, IC50=8.29 nM, reduces oxidative stress, neuroprotective in neuroinflammation.Fórmula:C26H29N3O4Cor e Forma:SolidPeso molecular:447.53MK-4409
CAS:MK-4409, a potent and selective fatty acid amide hydrolase (FAAH) inhibitor, is being investigated for the treatment of inflammatory and neuropathic pain.Fórmula:C22H17ClFN3O2SPureza:99.58% - 99.87%Cor e Forma:White SolidPeso molecular:441.91VDM 11
CAS:anandamide transport inhibitorFórmula:C27H39NO2Pureza:98%Cor e Forma:SolidPeso molecular:409.6OL-135
CAS:OL-135: CNS-accessible, potent, selective FAAH inhibitor with analgesic effects in animals, no motor impairment.Fórmula:C21H22N2O2Cor e Forma:SolidPeso molecular:334.41
