FAAH
A Hidrolase de Amida de Ácido Graxo (FAAH) é uma enzima que degrada amidas de ácidos graxos, incluindo endocanabinoides como a anandamida. Esses compostos estão envolvidos na regulação da dor, humor, apetite e memória. A inibição da FAAH pode aumentar os níveis dessas moléculas de sinalização, oferecendo potenciais benefícios terapêuticos para dor, ansiedade e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de inibidores de FAAH para apoiar sua pesquisa em neurociência, manejo da dor e sinalização endocanabinoide.
Foram encontrados 64 produtos de "FAAH"
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AA38-3
CAS:AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH)Fórmula:C12H14N2O4Pureza:99.56%Cor e Forma:SolidPeso molecular:250.25JZL195
CAS:JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.Fórmula:C24H23N3O5Pureza:99.81%Cor e Forma:SolidPeso molecular:433.46Biochanin A
CAS:Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Fórmula:C16H12O5Pureza:97.1% - 98.97%Cor e Forma:SolidPeso molecular:284.26PF-04457845
CAS:PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Fórmula:C23H20F3N5O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:455.43Ref: TM-T4323
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg84,00€25mg155,00€50mg222,00€100mg396,00€200mg515,00€MAGL-IN-4
CAS:MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.Fórmula:C18H21ClN2O4Pureza:99.79%Cor e Forma:SolidPeso molecular:364.82Ref: TM-T9687
1mg133,00€5mg326,00€1mL*10mM (DMSO)353,00€10mg485,00€25mg803,00€50mg1.063,00€100mg1.431,00€URB-597
CAS:URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Fórmula:C20H22N2O3Pureza:97.20% - 98.24%Cor e Forma:SolidPeso molecular:338.4FAAH-IN-8
CAS:FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 of 6.7 nM and a Ki of 5 nM. It exhibits high blood-brain permeability and a significant antioxidant profile without neurotoxicity [1].Fórmula:C18H14N4OCor e Forma:SolidPeso molecular:302.33AKU-005
CAS:AKU-005 is a dual inhibitor of FAAH and MAGL, exhibiting IC50 values of 63 nM and 389 nM against rat and human FAAH, respectively. This compound has potential for researching trigeminal nociceptive hypersensitivity.Fórmula:C20H21N5OCor e Forma:SolidPeso molecular:347.41JNJ-40413269
CAS:JNJ-40413269 inhibits FAAH, engages central targets, and is effective in rat neuropathic pain.Fórmula:C19H15ClF3N3OCor e Forma:SolidPeso molecular:393.79SA57
CAS:SA57 is a potent, selective inhibitor of FAAH(IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH).Fórmula:C17H23ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:338.83Acetylhydrolase-IN-1
CAS:Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).Fórmula:C23H48NO7PPureza:98%Cor e Forma:SolidPeso molecular:481.6OL-135
CAS:OL-135: CNS-accessible, potent, selective FAAH inhibitor with analgesic effects in animals, no motor impairment.Fórmula:C21H22N2O2Cor e Forma:SolidPeso molecular:334.41FAAH-IN-7
FAAH-IN-7: Reversible FAAH inhibitor, IC50=8.29 nM, reduces oxidative stress, neuroprotective in neuroinflammation.Fórmula:C26H29N3O4Cor e Forma:SolidPeso molecular:447.53FAAH-IN-5
CAS:FAAH-IN-5 (Compound 7) selectively, irreversibly inhibits FAAH (IC50: 10.5 nM) with low PAMPA permeability.Fórmula:C21H19N3O6SCor e Forma:SolidPeso molecular:441.46URB-694
CAS:URB-694 is a fatty acid amide hydrolase (FAAH) inhibitor.Fórmula:C19H21NO3Cor e Forma:SolidPeso molecular:311.37MDPD
CAS:MDPD boosts AtFAAH, the enzyme degrading NAEs in Arabidopsis, reducing NAE 12:0's growth inhibition.Fórmula:C21H19N3O3Cor e Forma:SolidPeso molecular:361.39Arachidonyl serotonin
CAS:Dual FAAH inhibitor/TRPV1 antagonistFórmula:C30H42N2O2Pureza:98%Cor e Forma:SolidPeso molecular:462.67URB532
CAS:URB532 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor.Fórmula:C18H21NO3Pureza:98%Cor e Forma:SolidPeso molecular:299.36FAAH inhibitor 1
CAS:FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Fórmula:C24H23N3O3S3Pureza:99.6%Cor e Forma:SolidPeso molecular:497.65Ref: TM-T11256
1mg38,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg124,00€25mg203,00€50mg294,00€100mg411,00€200mg553,00€
