PPAR
Os receptores ativados por proliferadores de peroxissomas (PPARs) são um grupo de proteínas receptoras nucleares que funcionam como fatores de transcrição, regulando a expressão de genes envolvidos no metabolismo, particularmente no armazenamento de ácidos graxos e no metabolismo da glicose. Inibidores de PPAR são ferramentas importantes para o estudo de distúrbios metabólicos como diabetes, obesidade e doenças cardiovasculares. Esses inibidores podem modular o metabolismo lipídico, a sensibilidade à insulina e a inflamação, tornando-os valiosos na pesquisa terapêutica. Na CymitQuimica, oferecemos uma gama de inibidores de PPAR para apoiar sua pesquisa em doenças metabólicas, endocrinologia e desenvolvimento de medicamentos.
Foram encontrados 164 produtos de "PPAR"
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T0070907
CAS:<p>T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.</p>Fórmula:C12H8ClN3O3Pureza:98.25% - 99.98%Cor e Forma:SolidPeso molecular:277.66Angeloylgomisin H
CAS:<p>Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.</p>Fórmula:C28H36O8Pureza:99.84% - 99.95%Cor e Forma:SolidPeso molecular:500.58Oleuropein
CAS:<p>Oleuropein is an antioxidant polyphenol isolated from olive leaf.</p>Fórmula:C25H32O13Pureza:98% - 99.95%Cor e Forma:Brown PowderPeso molecular:540.51GSK0660
CAS:<p>GSK0660 is an antagonist and inverse agonist of PPARβ/δ.</p>Fórmula:C19H18N2O5S2Pureza:99.26% - ≥95%Cor e Forma:SolidPeso molecular:418.49Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Cor e Forma:SolidPeso molecular:393.89EPI-001
CAS:<p>EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.</p>Fórmula:C21H27ClO5Pureza:99% - 99.67%Cor e Forma:SolidPeso molecular:394.89Clofibrate
CAS:<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Fórmula:C12H15ClO3Pureza:98.77%Cor e Forma:Oil LiquidPeso molecular:242.70DG172 dihydrochloride
CAS:<p>DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).</p>Fórmula:C20H22BrCl2N3Pureza:99.87%Cor e Forma:SolidPeso molecular:455.2L-165041
CAS:<p>L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)</p>Fórmula:C22H26O7Pureza:97.97%Cor e Forma:SolidPeso molecular:402.44GSK3787
CAS:<p>GSK3787 is a specific and irreversible PPARδ inhibitor（pIC50= 6.6）.</p>Fórmula:C15H12ClF3N2O3SPureza:98% - 99.56%Cor e Forma:SolidPeso molecular:392.78Oroxin A
CAS:<p>Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.</p>Fórmula:C21H20O10Pureza:98.05% - 99.74%Cor e Forma:SolidPeso molecular:432.38AMG131
CAS:<p>AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for</p>Fórmula:C21H12Cl4N2O3SPureza:99.37%Cor e Forma:SolidPeso molecular:514.21Gypenoside XLIX
CAS:<p>Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry condition</p>Fórmula:C52H86O21Pureza:97.05% - 99.78%Cor e Forma:SolidPeso molecular:1047.23Elafibranor
CAS:<p>Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with</p>Fórmula:C22H24O4SPureza:98.42% - 98.78%Cor e Forma:SolidPeso molecular:384.49Cinnamyl alcohol
CAS:<p>Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.</p>Fórmula:C9H10OPureza:99.00%Cor e Forma:Colourless LiquidPeso molecular:134.18Tesaglitazar
CAS:<p>Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα</p>Fórmula:C20H24O7SPureza:99.95%Cor e Forma:SolidPeso molecular:408.47Pparδ agonist 2
CAS:<p>Pparδ agonist 2 is an agonist of PPARδ.</p>Fórmula:C20H18F3N3O3SPureza:98%Cor e Forma:SolidPeso molecular:437.44FTX-6746
CAS:<p>FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.</p>Fórmula:C16H7ClF2N2OPureza:98.68%Cor e Forma:SolidPeso molecular:316.6913-Oxo-9E,11E-octadecadienoic acid
CAS:<p>13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.</p>Fórmula:C18H30O3Pureza:98%Cor e Forma:SolidPeso molecular:294.43Peliglitazar racemate
CAS:<p>Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesity</p>Fórmula:C30H30N2O7Pureza:97.75%Cor e Forma:SolidPeso molecular:530.57
