HMG-CoA Reductase
A HMG-CoA Redutase é uma enzima chave na via do mevalonato, responsável pela síntese de colesterol e outros isoprenoides. Inibidores da HMG-CoA redutase, comumente conhecidos como estatinas, são amplamente utilizados para reduzir os níveis de colesterol e o risco de doenças cardiovasculares. Estes inibidores também têm potenciais benefícios na pesquisa sobre câncer e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma variedade de inibidores da HMG-CoA redutase para apoiar sua pesquisa em metabolismo lipídico, saúde cardiovascular e desenvolvimento terapêutico.
Foram encontrados 33 produtos de "HMG-CoA Reductase"
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Lovastatin hydroxy acid sodium
CAS:Lovastatin Sodium is an HMG-CoA reductase inhibitor.Fórmula:C24H38NaO6Cor e Forma:SolidPeso molecular:445.54(3S,5R)-Fluvastatin sodium
CAS:(3S,5R)-Fluvastatin sodium: synthetic HMG-CoA reductase inhibitor, IC50 8 nM, boosts vascular cell antioxidant defense.Fórmula:C24H26FNNaO4Pureza:98%Cor e Forma:SolidPeso molecular:434.463L 669262
CAS:L 669262 is a potent inhibitor of HMG-CoA reductase.Fórmula:C25H36O6Cor e Forma:SolidPeso molecular:432.55Simvastatin acid calcium hydrate
CAS:Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.Fórmula:C25H40O6Cor e Forma:SolidPeso molecular:436.28249Crilvastatin
CAS:Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.Fórmula:C14H23NO3Pureza:98.69% - 99.54%Cor e Forma:SolidPeso molecular:253.342'-Ethyl Simvastatin
CAS:2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.Fórmula:C23H34O5Pureza:98%Cor e Forma:SolidPeso molecular:390.51(Z)-Pitavastatin calcium
CAS:(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase.Fórmula:C50H50CaF2N2O8Pureza:98%Cor e Forma:SolidPeso molecular:885.031Dalvastatin
CAS:Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepaticFórmula:C24H31FO3Pureza:98.07%Cor e Forma:SolidPeso molecular:386.5(3R,5R)-Rosuvastatin calcium
CAS:(3R,5R)-Rosuvastatin, a potential impurity detected in bulk rosuvastatin formulations, arises as a degradation product through various stresses including acid or base hydrolysis, thermal, photolytic, hydrolytic, oxidative stress, or during storage. This compound is associated with the HMG-CoA reductase inhibitor class to which rosuvastatin belongs.Fórmula:C22H28FN3O6SCaCor e Forma:SolidPeso molecular:500.6Rosuvastatin zinc salt
CAS:Rosuvastatin zinc salt (Rosuvastatin zinc), a zinc-infused variant of Rosuvastatin, functions as an HMG-CoA reductase inhibitor, utilized primarily inFórmula:C44H54F2N6O12S2ZnCor e Forma:SolidPeso molecular:1026.47QH536
CAS:QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.Fórmula:C33H49N3O3Cor e Forma:SolidPeso molecular:535.76Bemfivastatin hemicalcium
CAS:Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.Fórmula:C34H36FN2O6CaCor e Forma:SolidPeso molecular:607.67L 668411
CAS:L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.Fórmula:C19H30O5Pureza:98%Cor e Forma:SolidPeso molecular:338.44
