Sintase de Ácidos graxos
A sintase de ácidos graxos (FAS) é um complexo multi-enzimático responsável pela síntese de ácidos graxos de cadeia longa. A superexpressão de FAS está associada a vários distúrbios metabólicos, incluindo obesidade, diabetes e câncer. Inibir a FAS pode reduzir a biossíntese de lipídios e induzir apoptose em células cancerígenas, tornando-a um alvo promissor para a terapia contra o câncer e a pesquisa em doenças metabólicas. Na CymitQuimica, oferecemos uma variedade de inibidores de FAS para apoiar sua pesquisa em oncologia, metabolismo e desenvolvimento terapêutico.
Foram encontrados 32 produtos de "Sintase de Ácidos graxos"
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FASN-IN-3
CAS:<p>FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).</p>Fórmula:C24H24N4OPureza:97.41%Cor e Forma:SolidPeso molecular:384.47Denifanstat
CAS:<p>Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.</p>Fórmula:C27H29N5OPureza:98.33% - 99.35%Cor e Forma:SolidPeso molecular:439.55PF429242 dihydrochloride
CAS:<p>PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).</p>Fórmula:C25H37Cl2N3O2Pureza:99.68%Cor e Forma:SolidPeso molecular:482.49trans-C75
CAS:<p>trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).</p>Fórmula:C14H22O4Pureza:98.88% - 99.57%Cor e Forma:White To Off-White SolidPeso molecular:254.32CTL-12
<p>CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase.</p>Fórmula:C22H21ClN4O4Cor e Forma:SolidPeso molecular:440.88Betulin ditosylate
CAS:<p>Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.</p>Fórmula:C44H62O6S2Cor e Forma:SolidPeso molecular:751.09IPI-9119
CAS:<p>IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).</p>Fórmula:C24H19F2N5O5Pureza:99.81%Cor e Forma:SolidPeso molecular:495.43FASN-IN-4 tosylate
CAS:<p>FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.</p>Fórmula:C33H35N3O7S2Cor e Forma:SolidPeso molecular:649.78Fasnall HCl
<p>Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.</p>Fórmula:C19H23ClN4SPureza:99.9%Cor e Forma:SoildPeso molecular:374.93CTL-06
<p>CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 μM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase and</p>Fórmula:C21H21ClN4O4Cor e Forma:SolidPeso molecular:428.87ACSS2-IN-2
CAS:<p>MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.</p>Fórmula:C21H19F2N3O4Pureza:99.5%Cor e Forma:SoildPeso molecular:415.39Lipid Metabolism Compound Library
<p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>Cor e Forma:Odour SolidFASN Protein, Human, Recombinant (His)
<p>FASN Protein, Human, Recombinant (His) is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:35.26 kDa (predicted)Anti-FASN Antibody (6U56)
<p>Anti-FASN Antibody (6U56) is an antibody targeting FASN. Anti-FASN Antibody (6U56) can be used in ELISA, IF, FCM.</p>Cor e Forma:Odour LiquidBI 99179
CAS:<p>BI 99179 is a selective and potent inhibitor of type I fatty acid synthase (FAS), a tool compound for targeting FAS for cancer research.</p>Fórmula:C23H25N3O3Pureza:98.73%Cor e Forma:SolidPeso molecular:391.46FASN Protein, Mouse, Recombinant (His)
<p>FASN Protein, Mouse, Recombinant (His) is expressed in E.</p>Pureza:≥ 95 % as determined by SDS-PAGE. - ≥ 95 % as determined by SDS-PAGE.Cor e Forma:Lyophilized PowderPeso molecular:34.23 kDa (predicted)VY-3-135
CAS:<p>VY-3-135 is an orally active, stable and specific acetyl-CoA synthetase 2 (ACSS2) inhibitor.Cost-effective and quality-assured.</p>Fórmula:C26H27N3O3Pureza:99.25% - 99.79%Cor e Forma:SolidPeso molecular:429.51FT113
CAS:<p>FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity</p>Fórmula:C22H20FN3O4Pureza:97.05%Cor e Forma:SolidPeso molecular:409.41TVB-3664
CAS:<p>TVB-3664 is an orally active, selective, highly bioavailable fatty acid synthase inhibitor (FASN).Cost-effective and quality-assured.</p>Fórmula:C25H23F3N4O2Pureza:99.17% - 99.64%Cor e Forma:SolidPeso molecular:468.47PF 429242
CAS:<p>PF-429242 inhibits SREBP site 1 protease selectively (IC50: 0.175 μM); reduces cholesterol synthesis in CHO cells (IC50: 0.53 μM).</p>Fórmula:C25H35N3O2Pureza:99.27%Cor e Forma:SolidPeso molecular:409.56Fas C-Terminal Tripeptide Acetate
<p>Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.</p>Fórmula:C18H33N3O8Pureza:99.12%Cor e Forma:SolidPeso molecular:419.47HS79
CAS:<p>HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.</p>Fórmula:C19H22N4SPureza:98%Cor e Forma:SolidPeso molecular:338.47HS80
CAS:<p>HS-80, a Fasnall enantiomer, selectively inhibits FASN, blocking lipid synthesis (IC50: 7.13 μM).</p>Fórmula:C19H22N4SPureza:98%Cor e Forma:SolidPeso molecular:338.47FASN-IN-5
CAS:<p>FASN-IN-5 is a FASN inhibitor, useful for studying cancer and metabolic diseases.</p>Fórmula:C29H26N4O2Pureza:99.88%Cor e Forma:SolidPeso molecular:462.54FASN-IN-4
CAS:<p>FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.</p>Fórmula:C26H27N3O4SPureza:98%Cor e Forma:SolidPeso molecular:477.58C75
CAS:<p>C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).</p>Fórmula:C14H22O4Pureza:98.84% - >99.99%Cor e Forma:SolidPeso molecular:254.32Malic enzyme inhibitor ME1
CAS:<p>Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.</p>Fórmula:C20H21N3O3Pureza:99.84%Cor e Forma:SolidPeso molecular:351.4FASN-IN-1
CAS:<p>FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme</p>Fórmula:C18H25N3O3S2Pureza:99.92% - >99.99%Cor e Forma:SolidPeso molecular:395.54SREBP/SCAP-IN-2
CAS:<p>SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].</p>Fórmula:C27H37ClF2N4OCor e Forma:SolidPeso molecular:507.06SREBP/SCAP-IN-1
CAS:<p>SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].</p>Fórmula:C28H40F2N4OCor e Forma:SolidPeso molecular:486.64FAS-IN-1 Tosylate
<p>FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.</p>Fórmula:C33H35N3O7S2Pureza:98%Cor e Forma:SolidPeso molecular:649.78PFM046
CAS:<p>PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.</p>Fórmula:C29H42O2Cor e Forma:SolidPeso molecular:422.643
