Sintase de Ácidos graxos
A sintase de ácidos graxos (FAS) é um complexo multi-enzimático responsável pela síntese de ácidos graxos de cadeia longa. A superexpressão de FAS está associada a vários distúrbios metabólicos, incluindo obesidade, diabetes e câncer. Inibir a FAS pode reduzir a biossíntese de lipídios e induzir apoptose em células cancerígenas, tornando-a um alvo promissor para a terapia contra o câncer e a pesquisa em doenças metabólicas. Na CymitQuimica, oferecemos uma variedade de inibidores de FAS para apoiar sua pesquisa em oncologia, metabolismo e desenvolvimento terapêutico.
Foram encontrados 38 produtos de "Sintase de Ácidos graxos"
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FGH10019
CAS:FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).Fórmula:C18H19N3O2S2Pureza:98.93%Cor e Forma:SolidPeso molecular:373.49Ref: TM-T7798
1mg70,00€5mg152,00€1mL*10mM (DMSO)156,00€10mg212,00€25mg355,00€50mg505,00€100mg685,00€200mg888,00€PF 429242
CAS:PF-429242 inhibits SREBP site 1 protease selectively (IC50: 0.175 μM); reduces cholesterol synthesis in CHO cells (IC50: 0.53 μM).Fórmula:C25H35N3O2Pureza:99.27%Cor e Forma:SolidPeso molecular:409.56Ref: TM-T4317
1mg44,00€2mg55,00€5mg99,00€1mL*10mM (DMSO)99,00€10mg173,00€25mg384,00€50mg560,00€100mg817,00€TVB-3664
CAS:TVB-3664 is an orally active, selective, highly bioavailable fatty acid synthase inhibitor (FASN).Cost-effective and quality-assured.Fórmula:C25H23F3N4O2Pureza:99.17% - 99.64%Cor e Forma:SolidPeso molecular:468.47Ref: TM-T17181
1mg114,00€5mg268,00€1mL*10mM (DMSO)294,00€10mg432,00€25mg708,00€50mg1.044,00€100mg1.423,00€Fatostatin
CAS:Fatostatin inhibits SREBP-1/2 by binding to SCAP, blocking their ER-Golgi transport.Fórmula:C18H18N2SPureza:99.92%Cor e Forma:SolidPeso molecular:294.41Ref: TM-T9266
2mg34,00€5mg48,00€1mL*10mM (DMSO)50,00€10mg70,00€25mg112,00€50mg182,00€100mg309,00€200mg465,00€FT113
CAS:FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activityFórmula:C22H20FN3O4Pureza:97.05%Cor e Forma:SolidPeso molecular:409.41HS80
CAS:HS-80, a Fasnall enantiomer, selectively inhibits FASN, blocking lipid synthesis (IC50: 7.13 μM).Fórmula:C19H22N4SPureza:98%Cor e Forma:SolidPeso molecular:338.47FASN-IN-5
CAS:FASN-IN-5 is a FASN inhibitor, useful for studying cancer and metabolic diseases.Fórmula:C29H26N4O2Pureza:99.88%Cor e Forma:SolidPeso molecular:462.54FASN-IN-4
CAS:FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.Fórmula:C26H27N3O4SPureza:98%Cor e Forma:SolidPeso molecular:477.58HS79
CAS:HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.Fórmula:C19H22N4SPureza:98%Cor e Forma:SolidPeso molecular:338.47C75
CAS:C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).Fórmula:C14H22O4Pureza:98.84% - >99.99%Cor e Forma:SolidPeso molecular:254.32Ref: TM-T10657
1mg46,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg154,00€25mg299,00€50mg477,00€100mg757,00€Malic enzyme inhibitor ME1
CAS:Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.Fórmula:C20H21N3O3Pureza:99.84%Cor e Forma:SolidPeso molecular:351.4Ref: TM-T11940
1mg73,00€1mL*10mM (DMSO)157,00€5mg188,00€10mg344,00€25mg585,00€50mg833,00€100mg1.121,00€500mg2.270,00€SREBP/SCAP-IN-2
CAS:SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].Fórmula:C27H37ClF2N4OCor e Forma:SolidPeso molecular:507.061,3-Dipalmitoyl-2-Docosahexaenoyl Glycerol
CAS:1,3-Dipalmitoyl-2-docosahexaenoyl glycerol, a triacylglycerol, features palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position. Its dietary administration (30 g/kg) has been shown to decrease hepatic triglyceride and cholesterol levels in mice.Fórmula:C57H98O6Cor e Forma:SolidPeso molecular:879.38FAS-IN-1 Tosylate
FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.
Fórmula:C33H35N3O7S2Pureza:98%Cor e Forma:SolidPeso molecular:649.78SREBP/SCAP-IN-1
CAS:SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].Fórmula:C28H40F2N4OCor e Forma:SolidPeso molecular:486.64FASN-IN-1
CAS:FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzymeFórmula:C18H25N3O3S2Pureza:99.92% - >99.99%Cor e Forma:SolidPeso molecular:395.54PFM046
CAS:PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.Fórmula:C29H42O2Cor e Forma:SolidPeso molecular:422.643ONL-1204
CAS:ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.Fórmula:C71H100N18O16Cor e Forma:SolidPeso molecular:1461.66
