Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 302 produtos de "Desidrogenase"
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hDHODH-IN-3
CAS:hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Fórmula:C18H19BrN4O2Pureza:99.871%Cor e Forma:SolidPeso molecular:403.27Ref: TM-T11025
500mgA consultar1mg60,00€2mg88,00€5mg133,00€1mL*10mM (DMSO)142,00€10mg203,00€25mg335,00€50mg474,00€100mg623,00€ALDH1A1-IN-3
CAS:ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.Fórmula:C31H36F3N5O4Cor e Forma:SolidPeso molecular:599.64KM04416
CAS:KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.Fórmula:C12H11NO3SPureza:99.88%Cor e Forma:SolidPeso molecular:249.29hDHODH-IN-9
CAS:hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.Fórmula:C21H21NO4Cor e Forma:SolidPeso molecular:351.4DHODH-IN-13
CAS:DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.Fórmula:C10H6F3N3O3Pureza:99.66%Cor e Forma:SolidPeso molecular:273.17DHODH-IN-15
CAS:DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.Fórmula:C15H11N3O3Pureza:99.8%Cor e Forma:SolidPeso molecular:281.27Ref: TM-T11024
1mg109,00€1mL*10mM (DMSO)225,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€200mg1.378,00€Genz-669178
CAS:Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).Fórmula:C17H14N4OSPureza:98%Cor e Forma:SolidPeso molecular:322.38DHODH-IN-17
CAS:DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.Fórmula:C12H9ClN2O2Pureza:99.52% - 99.99%Cor e Forma:SolidPeso molecular:248.67Ref: TM-T60364
5mg43,00€1mL*10mM (DMSO)46,00€10mg65,00€25mg119,00€50mg172,00€100mg255,00€200mg356,00€EN40
CAS:EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).Fórmula:C13H15NO2Cor e Forma:SolidPeso molecular:217.26DHODH-IN-1
CAS:DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.Fórmula:C21H20F3N3O2Pureza:99.76%Cor e Forma:SolidPeso molecular:403.4hDHODH-IN-5
CAS:hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).Fórmula:C21H21F3N2O2Pureza:99.55%Cor e Forma:SolidPeso molecular:390.4Ref: TM-T11029
1mg80,00€5mg158,00€1mL*10mM (DMSO)172,00€10mg221,00€25mg356,00€50mg530,00€100mg755,00€p-Valerylphenol
CAS:p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.Fórmula:C11H14O2Pureza:99.87%Cor e Forma:White To Light Beige PowderPeso molecular:178.23M77976
CAS:M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.Fórmula:C17H16N2O3Pureza:99.92%Cor e Forma:SolidPeso molecular:296.32Manitimus
CAS:Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.Fórmula:C15H11F3N2O2Pureza:99.75% - 99.75%Cor e Forma:SolidPeso molecular:308.26Metapramine
CAS:Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.Fórmula:C16H18N2Pureza:99.03% - 99.67%Cor e Forma:SolidPeso molecular:238.3311β-HSD1-IN-1
CAS:11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.Fórmula:C18H14ClF4N3OPureza:99.84%Cor e Forma:SolidPeso molecular:399.77Ref: TM-T10160
1mg50,00€5mg105,00€1mL*10mM (DMSO)112,00€10mg155,00€25mg224,00€50mg314,00€100mg427,00€DHODH-IN-4
CAS:DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Fórmula:C17H12Cl2N2O2Pureza:99.34%Cor e Forma:SolidPeso molecular:347.2Ref: TM-T11027
1mg109,00€2mg163,00€5mg243,00€1mL*10mM (DMSO)248,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mg2.035,00€DHODH-IN-8
CAS:DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).Fórmula:C17H13ClN2O2Pureza:99.78%Cor e Forma:SolidPeso molecular:312.75Ref: TM-T11030
500mgA consultar1mg109,00€2mg163,00€1mL*10mM (DMSO)235,00€5mg241,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€11β-HSD1-IN-12
CAS:11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndromeFórmula:C19H27ClN2O3SPureza:99.89%Cor e Forma:SolidPeso molecular:398.95DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Fórmula:C22H18ClF6N3O3Cor e Forma:SolidPeso molecular:521.84
