Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 302 produtos de "Desidrogenase"
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ASP3662
CAS:ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.Fórmula:C19H16ClF3N4O2Cor e Forma:SolidPeso molecular:424.8TM-1
CAS:TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.Fórmula:C26H32N2O6Cor e Forma:SolidPeso molecular:468.54DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Fórmula:C17H13ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:312.75ALDH3A1-IN-2
CAS:ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.Fórmula:C11H14N2O3Cor e Forma:SolidPeso molecular:222.2411β-HSD1-IN-10
CAS:11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitiveFórmula:C16H10F3NO2Cor e Forma:SolidPeso molecular:305.2511β-HSD1-IN-9
CAS:11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.Fórmula:C13H9F3N2OCor e Forma:SolidPeso molecular:266.22DHODH-IN-21
CAS:DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.Fórmula:C20H19ClF4N6O4Cor e Forma:SolidPeso molecular:518.85BRD9185
CAS:BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.Fórmula:C23H21F6N3O2Pureza:98%Cor e Forma:SolidPeso molecular:485.42P1788
CAS:P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].Fórmula:C15H17NO3Cor e Forma:SolidPeso molecular:259.3ML-148
CAS:ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).Fórmula:C20H21N3OPureza:99.88%Cor e Forma:SolidPeso molecular:319.4Ref: TM-T38163
1mg60,00€5mg165,00€1mL*10mM (DMSO)188,00€10mg254,00€25mg459,00€50mg658,00€100mg935,00€200mg1.283,00€AMG-221
CAS:AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.Fórmula:C14H22N2OSPureza:98%Cor e Forma:SolidPeso molecular:266.4hDHODH-IN-11
CAS:hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.Fórmula:C24H23N3O3Cor e Forma:SolidPeso molecular:401.46MEDS433
CAS:MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.Fórmula:C20H11F4N3O2Cor e Forma:SolidPeso molecular:401.31Epostane
CAS:Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.Fórmula:C22H31NO3Pureza:>99.99%Cor e Forma:SolidPeso molecular:357.4911β-HSD1-IN-6
CAS:11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).Fórmula:C21H19ClN4OCor e Forma:SolidPeso molecular:378.86Nitrefazole
CAS:Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.Fórmula:C10H8N4O4Cor e Forma:SolidPeso molecular:248.19CM39
CAS:CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.Fórmula:C19H15FN4OSCor e Forma:SolidPeso molecular:366.41DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Fórmula:C26H26N4Cor e Forma:SolidPeso molecular:394.51PHGDH-IN-3
CAS:PHGDH-IN-3, an oral PHGDH blocker with 2.8 μM IC50, may help in cancer research.Fórmula:C24H18FN3O4S2Pureza:97.24% - 99.1%Cor e Forma:SolidPeso molecular:495.55DS18561882
CAS:DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.Fórmula:C28H31F3N4O6SPureza:98.19% - >99.99%Cor e Forma:SolidPeso molecular:608.63Ref: TM-T11103
1mg109,00€5mg260,00€1mL*10mM (DMSO)358,00€10mg409,00€25mg737,00€50mg1.198,00€100mg1.611,00€
