Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 302 produtos de "Desidrogenase"
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DSM421
CAS:DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shownFórmula:C14H11F5N6Pureza:99.67% - 99.82%Cor e Forma:SolidPeso molecular:358.27Ref: TM-T27214
1mg110,00€5mg259,00€1mL*10mM (DMSO)301,00€10mg353,00€25mg533,00€50mg718,00€100mg945,00€200mg1.251,00€PBRM
CAS:PBRM (17β-HSD1-IN-2) is a selective covalent inhibitor of 17β-HSD1, used in breast cancer and endometriosis research.Fórmula:C28H34BrNO2Pureza:99.56% - 99.59%Cor e Forma:SolidPeso molecular:496.48G6PD activator AG1
CAS:G6PD activator AG1 is a G6PD agonist that promotes G6PD oligomerization to a catalytically competent form.Fórmula:C24H30N4S2Pureza:98.38% - 99.51%Cor e Forma:SolidPeso molecular:438.65CPS-11
CAS:CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.Fórmula:C14H12N2O5Pureza:99.8% - 99.98%Cor e Forma:SolidPeso molecular:288.26PKUMDL-WQ-2101
CAS:PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.Fórmula:C14H11N3O6Pureza:99.57%Cor e Forma:SolidPeso molecular:317.25ALDH1A3-IN-2
CAS:ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.Fórmula:C13H17NOPureza:99.84%Cor e Forma:SolidPeso molecular:203.28CM037
CAS:CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminateFórmula:C21H25N3O3S2Pureza:99.77%Cor e Forma:SolidPeso molecular:431.57IGP-1
CAS:iGP-1 is a cell-permeable mitochondrial sn-Glycerol 3-phosphate dehydrogenase (mGPDH) inhibitor.Fórmula:C17H15N3O3Pureza:99.12% - 99.15%Cor e Forma:SolidPeso molecular:309.32Ref: TM-T25526
2mg34,00€5mg49,00€10mg71,00€1mL*10mM (DMSO)84,00€25mg126,00€50mg192,00€100mg304,00€200mg444,00€BMS-823778
CAS:BMS-823778 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) for the study of type 2 diabetes.Fórmula:C18H18ClN3OPureza:99.39% - 99.75%Cor e Forma:SolidPeso molecular:327.81Ref: TM-T71394
1mg164,00€2mg234,00€5mg389,00€10mg532,00€25mg820,00€50mg1.063,00€100mg1.350,00€200mg1.783,00€hDHODH-IN-7
CAS:hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Fórmula:C21H23FN4OPureza:99.87%Cor e Forma:SolidPeso molecular:366.43Ref: TM-T11031
1mg115,00€2mg172,00€5mg255,00€1mL*10mM (DMSO)266,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€IDH2R140Q-IN-2
CAS:IDH2R140Q-IN-2 is an IDH2R140Q inhibitor indicated for the study of acute myeloid leukaemia (AML).Fórmula:C21H18F6N6OPureza:99.92%Cor e Forma:SolidPeso molecular:484.4Qc1
CAS:Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.Fórmula:C23H16F3N3O2SPureza:99.75%Cor e Forma:SolidPeso molecular:455.45HSD-016
CAS:HSD-016: Oral 11β-HSD1 inhibitor, active in humans, mice, rats (IC50: 11, 1, 8 nM), potential for type 2 diabetes research.Fórmula:C21H21F7N2O3SPureza:99.40% - >99.99%Cor e Forma:SolidPeso molecular:514.46Ref: TM-T63569
1mg84,00€5mg280,00€1mL*10mM (DMSO)310,00€10mg439,00€25mg888,00€50mg1.485,00€100mg2.358,00€GSK321
CAS:GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.Fórmula:C28H28FN5O3Pureza:99.73%Cor e Forma:SolidPeso molecular:501.55DHODH-IN-22
CAS:DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.Fórmula:C21H21ClF4N6O5Cor e Forma:SolidPeso molecular:548.88Anticancer agent 122
CAS:Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use inFórmula:C18H15ClN2O2SCor e Forma:SolidPeso molecular:358.84AKR1C3-IN-6
CAS:AKR1C3-IN-6: Strong AKR1C3 inhibitor (IC50: 0.31 μM); weak on AKR1C2 (IC50: 73.23 μM); shows antitumor effects.Fórmula:C18H15F3N4O3Cor e Forma:SolidPeso molecular:392.3311α-Hydroxyprogesterone
CAS:11alpha-Hydroxyprogesterone, an inactive analogue of 11beta-Hydroxyprogesterone, serves as an experimental control. Meanwhile, 11beta-Hydroxyprogesterone functions as a potent inhibitor of 11β-Hydroxysteroid dehydrogenase and activates the human mineralocorticoid receptor in COS-7 cells, with an effective dose (ED)50 of 10 nM.Fórmula:C21H30O3Cor e Forma:SolidPeso molecular:330.468Tetrahydro-11-dehydrocorticosterone
CAS:Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].Fórmula:C21H32O4Cor e Forma:SolidPeso molecular:348.48HSD17B13-IN-3
CAS:HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].Fórmula:C22H21NO6S2Cor e Forma:SolidPeso molecular:459.54
