Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 302 produtos de "Desidrogenase"
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15-PGDH-IN-1
CAS:15-PGDH-IN-1: potent oral 15-PGDH inhibitor, IC50=3nM, useful for tissue repair research.Fórmula:C24H22N4O2Cor e Forma:SolidPeso molecular:398.46IDH889
CAS:IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).Fórmula:C23H25FN6O2Pureza:≥98%Cor e Forma:SolidPeso molecular:436.48YG1702
CAS:YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.Fórmula:C23H30N2O7SCor e Forma:SolidPeso molecular:478.56CHK-336
CAS:CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluriaFórmula:C24H20F2N4O4S2Cor e Forma:SolidPeso molecular:530.57hDHODH-IN-1
CAS:hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.Fórmula:C17H14N2O2Pureza:99.97%Cor e Forma:SolidPeso molecular:278.31Ref: TM-T11546
1mg34,00€5mg71,00€1mL*10mM (DMSO)78,00€10mg103,00€25mg200,00€50mg290,00€100mg404,00€200mg545,00€AZD 4017
CAS:AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).Fórmula:C22H33N3O3SPureza:99.61%Cor e Forma:SolidPeso molecular:419.58Ref: TM-T14388
1mg70,00€5mg152,00€1mL*10mM (DMSO)166,00€10mg260,00€25mg520,00€50mg750,00€100mg1.035,00€Anticancer agent 121
CAS:Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].Fórmula:C19H18N2O3SCor e Forma:SolidPeso molecular:354.42MK-0736
CAS:MK-0736 is a potent and selective 11β-HSD-1 inhibitor.Fórmula:C23H30F3N3O2SCor e Forma:SolidPeso molecular:469.56HSD17B13-IN-2
CAS:HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1Fórmula:C21H23F2NO4Cor e Forma:SolidPeso molecular:391.41S07-1066
CAS:S07-1066, an aldo-keto reductase 1C3 (AKR1C3) inhibitor, enhances doxorubicin (DOX) cytotoxicity by selectively inhibiting AKR1C3-mediated reduction of DOX andFórmula:C16H11Cl2FO2Pureza:98%Cor e Forma:SolidPeso molecular:325.16DHODH-IN-14
CAS:DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726.Fórmula:C15H7F4N3O3Pureza:99.81%Cor e Forma:SolidPeso molecular:353.23Ref: TM-T11023
500mgA consultar1mg109,00€2mg163,00€5mg243,00€1mL*10mM (DMSO)250,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€IDH1 Inhibitor 2
CAS:IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).Fórmula:C26H22N4OPureza:98%Cor e Forma:SolidPeso molecular:406.48PF-915275
CAS:PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.Fórmula:C18H14N4O2SPureza:99.58% - 99.61%Cor e Forma:SolidPeso molecular:350.39Ref: TM-T16510
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)85,00€10mg120,00€25mg241,00€50mg472,00€100mg685,00€500mg1.431,00€MK-0736 hydrochloride
CAS:MK-0736 hydrochloride is a potent and selective 11β-HSD-1 inhibitor.Fórmula:C23H31ClF3N3O2SCor e Forma:SolidPeso molecular:506.03α-Pyridoin
CAS:α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.Fórmula:C12H12N2O2Cor e Forma:SolidPeso molecular:216.2415-PGDH-IN-2
CAS:15-PGDH-IN-2 (Compound 2) is an inhibitor of 15-PGDH with an IC50 value of 0.274 nM. This compound is useful for research into hair loss, bone formation, gastric ulcer healing, and dermal wound healing [1].Fórmula:C16H13NO3S2Cor e Forma:SolidPeso molecular:331.41BI-3231
CAS:BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.Fórmula:C16H14F2N4O3SPureza:98.2%Cor e Forma:SolidPeso molecular:380.37Ref: TM-T73446
1mg69,00€5mg147,00€1mL*10mM (DMSO)164,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€200mg982,00€CB29
CAS:CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
Fórmula:C15H15N3O5SPureza:99.36%Cor e Forma:SolidPeso molecular:349.36KB-74935
CAS:KB-74935: enzyme inhibitor, mineralocorticoid blocker, treats cholesterol, hypolipidemia, neurological issues, Alzheimer's.Fórmula:C19H18ClF4N3O3SPureza:99.4%Cor e Forma:SolidPeso molecular:479.88ALDH2 modulator 1
CAS:ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
Fórmula:C18H18ClFN2O3Pureza:99.68%Cor e Forma:SoildPeso molecular:364.8
