Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 267 produtos de "Desidrogenase"
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BVT-2733 hydrochloride
CAS:<p>BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.</p>Fórmula:C17H22Cl2N4O3S2Cor e Forma:SolidPeso molecular:465.42MTHFD2-IN-3
<p>MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity</p>Fórmula:C22H19NO7SCor e Forma:SolidPeso molecular:441.45MCI-INI-3
CAS:<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Fórmula:C21H15N3O4Cor e Forma:SolidPeso molecular:373.36CM121
CAS:<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Fórmula:C24H17FN4O3SCor e Forma:SolidPeso molecular:460.48DHODH-IN-23
CAS:<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Fórmula:C24H21ClFNO4Pureza:99.7%Cor e Forma:SolidPeso molecular:441.88Osmanthuside H
CAS:<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Fórmula:C19H28O11Cor e Forma:SolidPeso molecular:432.422hDHODH-IN-16
<p>hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.</p>Fórmula:C18H20N2O2Cor e Forma:SolidPeso molecular:296.36D-Lactate dehydrogenase
CAS:<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Cor e Forma:SolidMTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Fórmula:C26H21F6N2O5Cor e Forma:SolidPeso molecular:555.45ALDH1A3-IN-1
CAS:<p>ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].</p>Fórmula:C13H18BrNOCor e Forma:SolidPeso molecular:284.192-Bromoacetamide
CAS:<p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>Fórmula:C2H4BrNOPureza:99.83%Cor e Forma:SolidPeso molecular:137.96Ketogestin
CAS:<p>Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.</p>Fórmula:C21H28O3Pureza:99.19%Cor e Forma:SolidPeso molecular:328.454-Isopropoxybenzaldehyde
CAS:<p>ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.</p>Fórmula:C10H12O2Pureza:99.00%Cor e Forma:SolidPeso molecular:164.2Aldehyde dehydrogenase (NAD(P))
CAS:<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Cor e Forma:SolidDSM265
CAS:<p>DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.</p>Fórmula:C14H12F7N5SPureza:99.79%Cor e Forma:SolidPeso molecular:415.33PKUMDL-WQ-2201
CAS:<p>PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.</p>Fórmula:C15H14ClN3O3SCor e Forma:SolidPeso molecular:351.81ALDH3A1-IN-1
CAS:<p>ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.</p>Fórmula:C13H18N2O3Pureza:99.86%Cor e Forma:SolidPeso molecular:250.29ABT-384
CAS:<p>ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.</p>Fórmula:C25H34F3N5O2Pureza:99.863%Cor e Forma:SolidPeso molecular:493.58ALDH1A2-IN-1
CAS:<p>ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.</p>Fórmula:C21H26N4O4SPureza:99.51%Cor e Forma:SolidPeso molecular:430.52DSM502
CAS:<p>DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.</p>Fórmula:C16H16F3N3OPureza:99.52%Cor e Forma:SolidPeso molecular:323.31
