Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 302 produtos de "Desidrogenase"
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(R)-GNE-140
CAS:(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.Fórmula:C25H23ClN2O3S2Pureza:98.25% - 98.91%Cor e Forma:SolidPeso molecular:499.04Succinyl phosphonate trisodium salt
CAS:Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)Fórmula:C4H4Na3O6PPureza:99.8% - ≥95%Cor e Forma:SolidPeso molecular:248.01SW033291
CAS:SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.Fórmula:C21H20N2OS3Pureza:97.26% - 99.02%Cor e Forma:SolidPeso molecular:412.59Ref: TM-T2121
1mg38,00€2mg50,00€5mg82,00€10mg113,00€25mg200,00€50mg334,00€100mg485,00€1mL*10mM (DMSO)82,00€3-Hydroxybenzaldehyde
CAS:3-Hydroxybenzaldehyde is a compound useful in organic synthesis.Fórmula:C7H6O2Pureza:99.60%Cor e Forma:DrypowderPeso molecular:122.126PGD-IN-S3
CAS:6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).Fórmula:C15H10O4Pureza:99.12%Cor e Forma:SolidPeso molecular:254.24Enasidenib
CAS:Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potentialFórmula:C19H17F6N7OPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:473.38Ref: TM-T2346
5mg44,00€10mg66,00€25mg87,00€50mg105,00€100mg137,00€200mg197,00€500mg333,00€1mL*10mM (DMSO)48,00€DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Fórmula:C20H15NO5Pureza:99.13%Cor e Forma:SolidPeso molecular:349.34Ref: TM-T37655
1mg73,00€5mg160,00€10mg236,00€25mg409,00€50mg595,00€100mg858,00€1mL*10mM (DMSO)170,00€Enasidenib mesylate
CAS:Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.Fórmula:C20H21F6N7O4SPureza:99.85%Cor e Forma:SolidPeso molecular:569.48GSK1940029
CAS:GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.Fórmula:C18H16Cl2N4O2Pureza:99.48% - 99.49%Cor e Forma:SolidPeso molecular:391.25Nedosiran
CAS:Nedosiran, a GalNAc-dsRNA conjugate for RNAi, targets LDH to treat primary hyperoxaluria and ESRD.Cor e Forma:SolidTriflupromazine
CAS:Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.Fórmula:C18H19F3N2SCor e Forma:SolidPeso molecular:352.42Nitrophenide
CAS:Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.Fórmula:C12H8N2O4S2Pureza:99.78%Cor e Forma:SolidPeso molecular:308.33hDHODH-IN-2
CAS:hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Fórmula:C19H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:304.349Chlorisondamine diiodide
CAS:Chlorisondamine diiodide is a selective nAChR antagonist and ganglionic blocker that persistently antagonizes partial central effects of nicotine.Fórmula:C14H20Cl4I2N2Pureza:99.97%Cor e Forma:SolidPeso molecular:611.94BI-4924
CAS:BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.Fórmula:C21H20Cl2N2O6SPureza:99.55%Cor e Forma:SolidPeso molecular:499.36DHODH-IN-12
CAS:DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Fórmula:C10H9N3O2Pureza:99.53%Cor e Forma:SolidPeso molecular:203.2Ref: TM-T11021
1mg73,00€5mg149,00€10mg213,00€25mg319,00€50mg447,00€100mg610,00€200mg823,00€1mL*10mM (DMSO)122,00€BI-135585
CAS:BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.Fórmula:C28H32N2O4Pureza:99.45% - 99.57%Cor e Forma:SolidPeso molecular:460.57673-A
CAS:673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.Fórmula:C15H13NOCor e Forma:SolidPeso molecular:223.27CM026
CAS:CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.Fórmula:C22H30N6O4Cor e Forma:SolidPeso molecular:442.51ML387
CAS:ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.Fórmula:C20H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:335.4
