Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 267 produtos de "Desidrogenase"
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PDK-IN-1
CAS:<p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>Fórmula:C20H16BrN7OCor e Forma:SolidPeso molecular:450.29MCI-INI-3
CAS:<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Fórmula:C21H15N3O4Cor e Forma:SolidPeso molecular:373.36BMS-770767
CAS:<p>BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.</p>Fórmula:C19H18ClN3O2Cor e Forma:SolidPeso molecular:355.82SW209049
CAS:<p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>Fórmula:C25H18N2O4SPureza:99.72%Cor e Forma:SolidPeso molecular:442.49DSM1465
<p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>Fórmula:C17H12ClF6N5O2Cor e Forma:SolidPeso molecular:467.75317β-HSD10-IN-1
CAS:<p>17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.</p>Fórmula:C16H13ClN4O3SPureza:98.47%Cor e Forma:SoildPeso molecular:376.82Osmanthuside H
CAS:<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Fórmula:C19H28O11Cor e Forma:SolidPeso molecular:432.422PDK-IN-2
<p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>Fórmula:C17H23AsCl2N2O2S2Cor e Forma:SolidPeso molecular:497.33MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Fórmula:C26H21F6N2O5Cor e Forma:SolidPeso molecular:555.45Diethanolamine hydrochloride
CAS:<p>Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.</p>Fórmula:C4H12ClNO2Pureza:99.69%Cor e Forma:SolidPeso molecular:141.6D-Lactate dehydrogenase
CAS:<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Cor e Forma:SolidhDHODH-IN-13
CAS:<p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>Cor e Forma:SoildOctanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Fórmula:C29H49N7NaO17P3SCor e Forma:SolidPeso molecular:915.7111β-HSD1 inibitor 19
CAS:<p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>Fórmula:C19H16ClF4N3O2SPureza:99.58%Cor e Forma:SoildPeso molecular:461.86MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Fórmula:C26H21F6N2NaO5Cor e Forma:SolidPeso molecular:578.44DHODH-IN-23
CAS:<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Fórmula:C24H21ClFNO4Pureza:99.7%Cor e Forma:SolidPeso molecular:441.88DHODH-IN-16
CAS:<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Fórmula:C24H25FN4O3Pureza:99.64%Cor e Forma:SolidPeso molecular:436.48Antiproliferative agent-13
CAS:<p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>Fórmula:C20H18N2O6Pureza:99.723%Cor e Forma:SolidPeso molecular:382.37DSM705
CAS:<p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>Fórmula:C19H19F3N6OCor e Forma:SolidPeso molecular:404.397Aldehyde dehydrogenase (NAD(P))
CAS:<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Cor e Forma:SolidALDH1A2-IN-1
CAS:<p>ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.</p>Fórmula:C21H26N4O4SPureza:99.51%Cor e Forma:SolidPeso molecular:430.52Ketogestin
CAS:<p>Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.</p>Fórmula:C21H28O3Pureza:99.19%Cor e Forma:SolidPeso molecular:328.45PKUMDL-WQ-2201
CAS:<p>PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.</p>Fórmula:C15H14ClN3O3SCor e Forma:SolidPeso molecular:351.81DSM265
CAS:<p>DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.</p>Fórmula:C14H12F7N5SPureza:99.79%Cor e Forma:SolidPeso molecular:415.332-Bromoacetamide
CAS:<p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>Fórmula:C2H4BrNOPureza:99.83%Cor e Forma:SolidPeso molecular:137.96ALDH1A3-IN-1
CAS:<p>ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].</p>Fórmula:C13H18BrNOCor e Forma:SolidPeso molecular:284.19DSM502
CAS:<p>DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.</p>Fórmula:C16H16F3N3OPureza:99.52%Cor e Forma:SolidPeso molecular:323.31ALDH3A1-IN-1
CAS:<p>ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.</p>Fórmula:C13H18N2O3Pureza:99.86%Cor e Forma:SolidPeso molecular:250.29ABT-384
CAS:<p>ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.</p>Fórmula:C25H34F3N5O2Pureza:99.863%Cor e Forma:SolidPeso molecular:493.584-Isopropoxybenzaldehyde
CAS:<p>ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.</p>Fórmula:C10H12O2Pureza:99.00%Cor e Forma:SolidPeso molecular:164.2Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Cor e Forma:SolidPeso molecular:375.37BVT 2733
CAS:<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Fórmula:C17H21ClN4O3S2Pureza:98% - 99.64%Cor e Forma:SolidPeso molecular:428.96Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Fórmula:C20H18FNO4CaCor e Forma:SolidPeso molecular:375.4AGI-6780
CAS:<p>AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.</p>Fórmula:C21H18F3N3O3S2Pureza:98.19% - 99.7%Cor e Forma:SolidPeso molecular:481.51Mutant IDH1-IN-1
CAS:<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Fórmula:C30H31FN4O2Pureza:99.49% - >99.99%Cor e Forma:SolidPeso molecular:498.59(E/Z)-Teriflunomide
CAS:<p>(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.</p>Fórmula:C12H9F3N2O2Pureza:99.49% - 99.76%Cor e Forma:White SolidPeso molecular:270.21Nitrofurazone
CAS:<p>Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.</p>Fórmula:C6H6N4O4Pureza:99.87%Cor e Forma:Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Peso molecular:198.14NCT-503
CAS:<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C20H23F3N4SPureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:408.48L-Allylglycine
CAS:<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Fórmula:C5H9NO2Pureza:≥98%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:115.13R162
CAS:<p>R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.</p>Fórmula:C17H12O3Pureza:96.21% - 98.15%Cor e Forma:SolidPeso molecular:264.28PfDHODH-IN-2
CAS:<p>PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.</p>Fórmula:C13H12ClNO3SPureza:98.9%Cor e Forma:SolidPeso molecular:297.76VER-246608
CAS:<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Fórmula:C28H23ClF2N4O4Pureza:98.5%Cor e Forma:SolidPeso molecular:552.96NCT-505
CAS:<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Fórmula:C27H28FN5O3SPureza:99.93%Cor e Forma:SolidPeso molecular:521.61BI-187004
CAS:<p>BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.</p>Fórmula:C21H18N4OPureza:98.63%Cor e Forma:SolidPeso molecular:342.39NCT-501 hydrochloride
CAS:<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Fórmula:C21H33ClN6O3Cor e Forma:SolidPeso molecular:452.98Galloflavin
CAS:<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Fórmula:C12H6O8Pureza:96.24% - 97.47%Cor e Forma:SolidPeso molecular:278.17CM10
CAS:<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Fórmula:C20H23N3OPureza:99.84%Cor e Forma:SolidPeso molecular:321.42DS-1001b
CAS:<p>DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)</p>Fórmula:C29H29Cl3FN3O4Pureza:99.81%Cor e Forma:SolidPeso molecular:608.92Perfluorooctanoic acid
CAS:<p>Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.</p>Fórmula:C8HF15O2Pureza:99.70%Cor e Forma:White To Off-White Powder OthersolidPeso molecular:414.07G6PDi-1
CAS:<p>G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.</p>Fórmula:C14H12N4OSPureza:98.69%Cor e Forma:SolidPeso molecular:284.34
