Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 302 produtos de "Desidrogenase"
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Triflupromazine
CAS:Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.Fórmula:C18H19F3N2SCor e Forma:SolidPeso molecular:352.42Nitrophenide
CAS:Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.Fórmula:C12H8N2O4S2Pureza:99.78%Cor e Forma:SolidPeso molecular:308.33hDHODH-IN-2
CAS:hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Fórmula:C19H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:304.349Chlorisondamine diiodide
CAS:Chlorisondamine diiodide is a selective nAChR antagonist and ganglionic blocker that persistently antagonizes partial central effects of nicotine.Fórmula:C14H20Cl4I2N2Pureza:99.97%Cor e Forma:SolidPeso molecular:611.94BI-4924
CAS:BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.Fórmula:C21H20Cl2N2O6SPureza:99.55%Cor e Forma:SolidPeso molecular:499.36DHODH-IN-12
CAS:DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Fórmula:C10H9N3O2Pureza:99.53%Cor e Forma:SolidPeso molecular:203.2Ref: TM-T11021
1mg73,00€5mg149,00€10mg213,00€25mg319,00€50mg447,00€100mg610,00€200mg823,00€1mL*10mM (DMSO)122,00€BI-135585
CAS:BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.Fórmula:C28H32N2O4Pureza:99.45% - 99.57%Cor e Forma:SolidPeso molecular:460.57673-A
CAS:673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.Fórmula:C15H13NOCor e Forma:SolidPeso molecular:223.27CM026
CAS:CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.Fórmula:C22H30N6O4Cor e Forma:SolidPeso molecular:442.51ML387
CAS:ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.Fórmula:C20H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:335.4Oxycinchophen
CAS:Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.Fórmula:C16H11NO3Pureza:98%Cor e Forma:SolidPeso molecular:265.26GW648495
CAS:GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.Fórmula:C16H13N5Pureza:98%Cor e Forma:SolidPeso molecular:275.31BVT-116429
CAS:BVT-116429 is an inhibitor of 11β-HSD1.Fórmula:C13H12F4N2OSPureza:98%Cor e Forma:SolidPeso molecular:320.31AGI-14100
CAS:AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.Fórmula:C29H22ClF4N5O3Pureza:99.91%Cor e Forma:SolidPeso molecular:599.96GA11
CAS:GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.Fórmula:C19H14N2Pureza:98%Cor e Forma:SolidPeso molecular:270.33UCK2 Inhibitor-2
CAS:UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.Fórmula:C28H23N3O4SPureza:98.76% - 99.25%Cor e Forma:SolidPeso molecular:497.57NCT-506
CAS:NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).Fórmula:C25H23FN4O3SPureza:98%Cor e Forma:SolidPeso molecular:478.54IMB-XMA0038
CAS:IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.Fórmula:C11H10N4O6Pureza:98.94% - 99.96%Cor e Forma:SolidPeso molecular:294.22hDHODH-IN-4
CAS:hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.Fórmula:C21H24N4O2Pureza:99.87%Cor e Forma:SolidPeso molecular:364.44SCH-451659
CAS:SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.Fórmula:C30H39Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:544.56INCB13739
CAS:INCB13739 is an 11β-HSD1 inhibitor that can be used in the study of hyperlipidemia and hypertriglyceridemia.Fórmula:C28H25N3O4Pureza:99.32%Cor e Forma:SoildPeso molecular:467.52Ref: TM-T60203
1mg94,00€5mg215,00€10mg344,00€25mg683,00€50mg945,00€100mg1.251,00€200mg1.701,00€1mL*10mM (DMSO)227,00€AZD8329
CAS:AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.Fórmula:C25H31N3O3Pureza:99.31%Cor e Forma:SolidPeso molecular:421.53Ref: TM-T14383
1mg87,00€5mg178,00€10mg295,00€25mg612,00€50mg897,00€100mg1.558,00€1mL*10mM (DMSO)203,00€ALDH1A1-IN-2
CAS:ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesityFórmula:C25H23ClN4O3SPureza:99.48%Cor e Forma:SolidPeso molecular:494.99MDH1-IN-2
CAS:MDH1-IN-2 is a potent MDH1 inhibitor with potential anticancer activity for the study of diseases related to the immune system.Fórmula:C25H33NO5Pureza:99.21%Cor e Forma:SolidPeso molecular:427.53Laflunimus
CAS:Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.Fórmula:C15H13F3N2O2Pureza:99.86%Cor e Forma:SolidPeso molecular:310.27RS6212
CAS:RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.Fórmula:C20H22N4O3SCor e Forma:SolidPeso molecular:398.48RORγt/DHODH-IN-2
CAS:RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).Fórmula:C25H30N4OSCor e Forma:SolidPeso molecular:434.6S07-2005 (racemic)
CAS:S07-2005 is a selective AKR1C3 inhibitor with IC50 of 0.13 μM, potential in enhancing cancer chemotherapy.Fórmula:C20H23NO6Cor e Forma:SolidPeso molecular:373.4DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Fórmula:C24H25F4N3O3Cor e Forma:SolidPeso molecular:479.47RV01
CAS:RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.Fórmula:C17H13NO2Pureza:99.93%Cor e Forma:SolidPeso molecular:263.29Ref: TM-T12781
1mg58,00€5mg128,00€10mg197,00€25mg334,00€50mg482,00€100mg637,00€200mg863,00€1mL*10mM (DMSO)141,00€hDHODH-IN-3
CAS:hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Fórmula:C18H19BrN4O2Pureza:99.871%Cor e Forma:SolidPeso molecular:403.27Ref: TM-T11025
1mg60,00€2mg88,00€5mg133,00€10mg203,00€25mg335,00€50mg474,00€100mg623,00€500mgA consultar1mL*10mM (DMSO)142,00€ALDH1A1-IN-3
CAS:ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.Fórmula:C31H36F3N5O4Cor e Forma:SolidPeso molecular:599.64KM04416
CAS:KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.Fórmula:C12H11NO3SPureza:99.88%Cor e Forma:SolidPeso molecular:249.29hDHODH-IN-9
CAS:hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.Fórmula:C21H21NO4Cor e Forma:SolidPeso molecular:351.4DHODH-IN-13
CAS:DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.Fórmula:C10H6F3N3O3Pureza:99.66%Cor e Forma:SolidPeso molecular:273.17DHODH-IN-15
CAS:DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.Fórmula:C15H11N3O3Pureza:99.8%Cor e Forma:SolidPeso molecular:281.27Ref: TM-T11024
1mg109,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€200mg1.378,00€1mL*10mM (DMSO)225,00€Genz-669178
CAS:Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).Fórmula:C17H14N4OSPureza:98%Cor e Forma:SolidPeso molecular:322.38DHODH-IN-17
CAS:DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.Fórmula:C12H9ClN2O2Pureza:99.52% - 99.99%Cor e Forma:SolidPeso molecular:248.67Ref: TM-T60364
5mg43,00€10mg65,00€25mg119,00€50mg172,00€100mg255,00€200mg356,00€1mL*10mM (DMSO)46,00€EN40
CAS:EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).Fórmula:C13H15NO2Cor e Forma:SolidPeso molecular:217.26DHODH-IN-1
CAS:DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.Fórmula:C21H20F3N3O2Pureza:99.76%Cor e Forma:SolidPeso molecular:403.4hDHODH-IN-5
CAS:hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).Fórmula:C21H21F3N2O2Pureza:99.55%Cor e Forma:SolidPeso molecular:390.4Ref: TM-T11029
1mg80,00€5mg158,00€10mg221,00€25mg356,00€50mg530,00€100mg755,00€1mL*10mM (DMSO)172,00€p-Valerylphenol
CAS:p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.Fórmula:C11H14O2Pureza:99.87%Cor e Forma:White To Light Beige PowderPeso molecular:178.23M77976
CAS:M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.Fórmula:C17H16N2O3Pureza:99.92%Cor e Forma:SolidPeso molecular:296.32Manitimus
CAS:Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.Fórmula:C15H11F3N2O2Pureza:99.75% - 99.75%Cor e Forma:SolidPeso molecular:308.26Metapramine
CAS:Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.Fórmula:C16H18N2Pureza:99.03% - 99.67%Cor e Forma:SolidPeso molecular:238.3311β-HSD1-IN-1
CAS:11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.Fórmula:C18H14ClF4N3OPureza:99.84%Cor e Forma:SolidPeso molecular:399.77Ref: TM-T10160
1mg50,00€5mg105,00€10mg155,00€25mg224,00€50mg314,00€100mg427,00€1mL*10mM (DMSO)112,00€DHODH-IN-4
CAS:DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Fórmula:C17H12Cl2N2O2Pureza:99.34%Cor e Forma:SolidPeso molecular:347.2Ref: TM-T11027
1mg109,00€2mg163,00€5mg243,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mg2.035,00€1mL*10mM (DMSO)248,00€DHODH-IN-8
CAS:DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).Fórmula:C17H13ClN2O2Pureza:99.78%Cor e Forma:SolidPeso molecular:312.75Ref: TM-T11030
1mg109,00€2mg163,00€5mg241,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€500mgA consultar1mL*10mM (DMSO)235,00€11β-HSD1-IN-12
CAS:11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndromeFórmula:C19H27ClN2O3SPureza:99.89%Cor e Forma:SolidPeso molecular:398.95DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Fórmula:C22H18ClF6N3O3Cor e Forma:SolidPeso molecular:521.84
