Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 267 produtos de "Desidrogenase"
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PDHK-IN-5
<p>PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.</p>Fórmula:C30H31N5O2Cor e Forma:SolidPeso molecular:493.6Deamino-NAD sodium
CAS:<p>Deamino-NAD sodium, a structural analog of NAD+, serves as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH) in glycolysis. It exhibits a Km of 2300 pm and a Kd of 112 pm.</p>Fórmula:C21H25N6NaO15P2Cor e Forma:SolidPeso molecular:686.39Etamicastat
CAS:<p>Etamicastat can be used in the research of cardiovascular diseases.</p>Fórmula:C14H15F2N3OSPureza:98%Cor e Forma:SolidPeso molecular:311.3511β-HSD2-IN-2
CAS:<p>11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.</p>Fórmula:C22H21NO2Pureza:99.61%Cor e Forma:SolidPeso molecular:331.41GSK864
CAS:<p>GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).</p>Fórmula:C30H31FN6O4Pureza:97.07%Cor e Forma:SolidPeso molecular:558.6MDH1/2-IN-1
CAS:<p>MDH1/2-IN-1 is an MDH1/2 inhibitor with IC50 values of 1.07 nM and 1.06 nM, respectively. It suppresses mitochondrial respiration and the HIF-1α pathway. MDH1/2-IN-1 exhibits significant antitumor potential and offers new avenues for developing drugs targeting cancer metabolism.</p>Fórmula:C25H33NO4Cor e Forma:SolidPeso molecular:411.534AXKO-0046
<p>AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.</p>Fórmula:C25H33N3Cor e Forma:SolidPeso molecular:375.55Indoluidin E
<p>Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.</p>Fórmula:C28H30N4O2Cor e Forma:SolidPeso molecular:454.56LDHA-IN-5
CAS:<p>LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary</p>Fórmula:C27H22FN7O6S3Cor e Forma:SolidPeso molecular:655.7hDHODH-IN-10
<p>hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.</p>Fórmula:C21H15ClF4N2O4Cor e Forma:SolidPeso molecular:470.8RORγt/DHODH-IN-1
CAS:<p>RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significant</p>Fórmula:C24H26ClF6N3O3SCor e Forma:SolidPeso molecular:585.99Etamicastat hydrochloride
CAS:<p>Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.</p>Fórmula:C14H16ClF2N3OSPureza:98.54%Cor e Forma:SolidPeso molecular:347.81CP-642931
CAS:<p>CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.</p>Fórmula:C17H25N7OPureza:99.67% - >99.99%Cor e Forma:SolidPeso molecular:343.43PS10
CAS:<p>PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of the pyruvate dehydrogenase complex.</p>Fórmula:C14H13NO6SPureza:99.01%Cor e Forma:SolidPeso molecular:323.32GNE-140 racemate
CAS:<p>GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.</p>Fórmula:C25H23ClN2O3S2Cor e Forma:SolidPeso molecular:499.04(S)-GNE-140
CAS:<p>(S)-GNE-140 is the less active enantiomer of GNE-140.</p>Fórmula:C25H23ClN2O3S2Cor e Forma:SolidPeso molecular:499.0511β-HSD1-IN-8
CAS:<p>11β-HSD1-IN-8 is a useful organic compound for research related to life sciences. The catalog number is T65743 and the CAS number is 386704-15-0.</p>Fórmula:C10H8F3NO3Cor e Forma:SolidPeso molecular:247.173
