Lipoxigenase
As lipoxigenases são uma família de enzimas que catalisam a oxigenação de ácidos graxos poli-insaturados, levando à produção de mediadores lipídicos bioativos, como os leucotrienos e as lipoxinas. Esses mediadores desempenham papéis críticos na inflamação, nas respostas imunes e no câncer. Inibidores de lipoxigenase são utilizados para estudar seu papel em doenças inflamatórias, asma e câncer. Na CymitQuimica, oferecemos uma variedade de inibidores de lipoxigenase para apoiar sua pesquisa em inflamação, oncologia e metabolismo lipídico.
Foram encontrados 133 produtos de "Lipoxigenase"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFórmula:C16H14N2SPureza:99.44%Cor e Forma:SolidPeso molecular:266.36Ref: TM-T77288
2mg37,00€5mg56,00€1mL*10mM (DMSO)58,00€10mg84,00€25mg126,00€50mg197,00€100mg330,00€200mg472,00€h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Fórmula:C22H30Cl2N6O3Cor e Forma:SolidPeso molecular:497.42ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Fórmula:C23H24FNO4Pureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:397.44Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Fórmula:C20H24N2O7Cor e Forma:SolidPeso molecular:404.419E 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Fórmula:C17H20ClN3O3S2Pureza:99.80%Cor e Forma:SoildPeso molecular:413.94Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Fórmula:C13H16N2O2RuCor e Forma:SolidPeso molecular:333.35(-)-Dihydroguaiaretic acid
(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.Fórmula:C20H26O4Cor e Forma:SolidPeso molecular:330.424LOX-IN-5
CAS:LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.Fórmula:C21H25FN4O2SCor e Forma:SolidPeso molecular:416.51mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Fórmula:C20H22N4O6SPeso molecular:446.126011-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Fórmula:C17H10N2O6Pureza:99.79%Cor e Forma:SolidPeso molecular:338.27Ref: TM-T21838
5mg54,00€1mL*10mM (DMSO)55,00€10mg86,00€25mg161,00€50mg245,00€100mg346,00€200mg474,00€CBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Fórmula:C13H14ClN3Pureza:99.93%Cor e Forma:SoildPeso molecular:247.72CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Fórmula:C16H19FN2O4Pureza:98%Cor e Forma:SolidPeso molecular:322.3315-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Fórmula:C22H21ClN2O4Cor e Forma:SolidPeso molecular:412.87Zileuton sodium
CAS:Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.Fórmula:C11H11N2NaO2SCor e Forma:SolidPeso molecular:258.27Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can TrustFórmula:C19H15NO4Cor e Forma:SolidPeso molecular:321.33β-Boswellic acid
CAS:β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemicFórmula:C30H48O3Pureza:99.2% - 99.96%Cor e Forma:Off-White SolidPeso molecular:456.70Ref: TM-TN1097
1mg58,00€5mg137,00€1mL*10mM (DMSO)161,00€10mg212,00€25mg363,00€50mg527,00€100mg747,00€Chebulagic acid
CAS:Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Fórmula:C41H30O27Pureza:97.82% - 99.8%Cor e Forma:SolidPeso molecular:954.66Ref: TM-TQ0180
1mg74,00€5mg157,00€10mg225,00€1mL*10mM (DMSO)244,00€25mg376,00€50mg560,00€100mg798,00€4-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Fórmula:C16H19N5SPureza:97.18%Cor e Forma:SolidPeso molecular:313.42Ref: TM-T8794
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg86,00€25mg156,00€50mg245,00€100mg403,00€200mg568,00€Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Fórmula:C9H10N2OPureza:97.24%Cor e Forma:White Solid Solid CrystallinePeso molecular:162.19ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.Fórmula:C12H13NO3Pureza:98.9%Cor e Forma:Off-White To Light Tan Crystalline PowderPeso molecular:219.24
