Fosfolipase
As fosfolipases são um grupo de enzimas que hidrolisam fosfolipídios em ácidos graxos e outras substâncias lipofílicas, desempenhando um papel crítico na biologia das membranas e na geração de moléculas sinalizadoras. Inibidores de fosfolipases são usados para estudar seu papel em doenças inflamatórias, distúrbios cardiovasculares e neurodegeneração. Esses inibidores também são valiosos na exploração de vias de sinalização lipídica e suas implicações nos mecanismos de doenças. Na CymitQuimica, oferecemos uma variedade de inibidores de fosfolipases para apoiar sua pesquisa em inflamação, metabolismo lipídico e sinalização celular.
Foram encontrados 84 produtos de "Fosfolipase"
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BIRM 271
CAS:BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.
Fórmula:C21H25N3OPureza:99.64%Cor e Forma:SoildPeso molecular:335.44MJ33 lithium salt
CAS:MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, inhibits PLA2 activity, and can be used to study acute lung injury.Fórmula:C22H43F3LiO6PPureza:99%Cor e Forma:SolidPeso molecular:498.48BMS493
CAS:BMS493 is an inverse agonist of RAR that inhibits retinoic acid-induced differentiation and inhibits the increase in phospholipase A2 activity.Fórmula:C29H24O2Pureza:99.12% - >99.99%Cor e Forma:SolidPeso molecular:404.5LEI-401
CAS:LEI-401 is a NAPE-PLD inhibitor.LEI-401 reduces the level of n-acyl ethanolamines in the brain of free-ranging mice and modulates their emotional behaviour.Fórmula:C24H31N5O2Pureza:99.79% - 99.79%Cor e Forma:SolidPeso molecular:421.54Phospholipase A2
CAS:Phospholipase A2 (PLA2) is an enzyme that hydrolyzes fatty acids present in the sn-2 position of phospholipids and is closely related to lipid metabolism.Cor e Forma:SolidPACOCF3
CAS:PACOCF3, a phospholipase A2 inhibitor, hinders Ca2+ signaling with an IC50 of 3.8 μM in renal cells.Fórmula:C17H31F3OPureza:99.93%Cor e Forma:SolidPeso molecular:308.42Bromoenol lactone
CAS:NeurokininBromoenol lactone ((6E)-Bromoenol lactone) is an iPLA2β and serine protease inhibitor that attenuates nicotine-induced breast cancer cell proliferation.Fórmula:C16H13BrO2Cor e Forma:SolidPeso molecular:317.18ST271
CAS:ST271 is an effective protein tyrosine kinase (PTK) inhibitor.
Fórmula:C16H20N2O2Pureza:98.94%Cor e Forma:SolidPeso molecular:272.34ML348
CAS:ML348 (GNF-Pf-1127) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).Fórmula:C18H17ClF3N3O3Pureza:99% - 99.88%Cor e Forma:SolidPeso molecular:415.79Ref: TM-T3439
2mg44,00€5mg65,00€10mg92,00€25mg215,00€50mg334,00€100mg537,00€200mg750,00€500mg1.134,00€BAPTA
CAS:BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.Fórmula:C22H24N2O10Pureza:97.21% - ≥95%Cor e Forma:White SolidPeso molecular:476.43N-(p-amylcinnamoyl) Anthranilic Acid
CAS:N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.Fórmula:C21H23NO3Pureza:99.35% - 99.67%Cor e Forma:SolidPeso molecular:337.411-Linoleoyl Glycerol
CAS:1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots.Fórmula:C21H38O4Pureza:98.95% - 99.15%Cor e Forma:Less Oil Colourless OilPeso molecular:354.52Varespladib
CAS:Varespladib (LY315920) inhibits hnsPLA2 effectively (IC50=7 nM), studied for sickle cell, VOC, and acute coronary syndrome.Fórmula:C21H20N2O5Pureza:99.97%Cor e Forma:SolidPeso molecular:380.39Ref: TM-T2044
1mg46,00€1mL*10mM (DMSO)81,00€5mg87,00€10mg144,00€25mg227,00€50mg338,00€100mg487,00€200mg705,00€Difluprednate
CAS:Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.Fórmula:C27H34F2O7Pureza:99.23% - 99.86%Cor e Forma:SolidPeso molecular:508.55Tanshinone I
CAS:Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.Fórmula:C18H12O3Pureza:98.31% - 98.70%Cor e Forma:SolidPeso molecular:276.29Rhamnetin
CAS:Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities.Fórmula:C16H12O7Pureza:99.61% - 99.905%Cor e Forma:SolidPeso molecular:316.26Ref: TM-TN1419
1mg60,00€5mg130,00€1mL*10mM (DMSO)137,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€Cambinol
CAS:Cambinol is a SIRT1/2 inhibitor (IC50: 56/59 μM), non-competitive with NAD, weak on SIRT5, and prompts apoptosis in lymphoma cells.Fórmula:C21H16N2O2SPureza:98.02% - 99.83%Cor e Forma:SolidPeso molecular:360.43Ref: TM-T4019
1mg38,00€2mg50,00€1mL*10mM (DMSO)63,00€5mg80,00€10mg117,00€25mg207,00€50mg333,00€100mg495,00€500mg1.071,00€CAY10594
CAS:CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Fórmula:C26H28N4O2Pureza:98%Cor e Forma:SolidPeso molecular:428.531-Naphthaleneacetic acid
CAS:1-Naphthaleneacetic acid, an auxin-like synthetic plant hormone, boosts rooting in horticulture.Fórmula:C12H10O2Pureza:98.67%Cor e Forma:Needles From Water White To Off White CrystalsPeso molecular:186.21ML-298
CAS:ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM).Fórmula:C22H23F3N4O2Pureza:99.35%Cor e Forma:SolidPeso molecular:432.44
