Receptor 5-HT
Os receptores 5-HT, também conhecidos como receptores de serotonina, são um grupo de receptores acoplados à proteína G (GPCRs) que mediam os efeitos da serotonina, um neurotransmissor envolvido na regulação do humor, ansiedade, sono, apetite e outros processos fisiológicos. Esses receptores são divididos em vários subtipos, cada um com funções e propriedades farmacológicas distintas. Moduladores de receptores 5-HT são amplamente estudados por seus papéis no tratamento da depressão, distúrbios de ansiedade e outras condições neuropsiquiátricas. Na CymitQuimica, oferecemos uma variedade de moduladores de receptores 5-HT de alta qualidade para apoiar sua pesquisa em neurofarmacologia, transtornos do humor e sinalização GPCR.
Foram encontrados 940 produtos de "Receptor 5-HT"
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Clozapine
CAS:<p>Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent.</p>Fórmula:C18H19ClN4Pureza:99.91% - 99.93%Cor e Forma:Yellow Crystals From Acetone-Petroleum Ether SolidPeso molecular:326.82PF-04995274
CAS:<p>PF-04995274: potent, selective partial 5-HT4R agonist; EC50 0.26-0.47 nM; brain penetrant; may treat Alzheimer's cognitive issues.</p>Fórmula:C23H32N2O6Pureza:99.52%Cor e Forma:SolidPeso molecular:432.51Alverine citrate
CAS:<p>Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.</p>Fórmula:C26H35NO7Pureza:98.53% - 99.43%Cor e Forma:CoaPeso molecular:473.57Mianserin hydrochloride
CAS:<p>Mianserin HCl (Org GB 94): a tetracyclic antidepressant; blocks alpha-adrenergic, H1, serotonin receptors; may induce drowsiness, hematological issues.</p>Fórmula:C18H21ClN2Pureza:99.63% - 99.82%Cor e Forma:White And Film Coated Tablet And Seem To Be White Or White-Like After Removing It'S Film CoatedPeso molecular:300.83Metoclopramide hydrochloride
CAS:<p>Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic.</p>Fórmula:C14H22ClN3O2·HClPureza:99.99%Cor e Forma:White To Off-White PowderPeso molecular:336.26Vabicaserin hydrochloride
CAS:<p>Vabicaserin hydrochloride (SCA 136) is a selective agonist of 5-hydroxytryptamine 2C (5-HT2C) receptor (EC50: 8 nM).</p>Fórmula:C15H21ClN2Pureza:98.32%Cor e Forma:SolidPeso molecular:264.79Risperidone
CAS:<p>Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.</p>Fórmula:C23H27FN4O2Pureza:99.73%Cor e Forma:Crystalline SolidPeso molecular:410.48Ondansetron hydrochloride dihydrate
CAS:<p>Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.</p>Fórmula:C18H19N3O·HCl·2H2OPureza:99.92%Cor e Forma:White Crystal PowderPeso molecular:365.86Tabernanthalog fumarate
CAS:<p>Tabernanthalog fumarate is a 5-HT2A agonist that promotes neuronal growth and reduces alcohol consumption in mice, producing antidepressant-like effects.</p>Fórmula:C18H22N2O5Pureza:99.83%Cor e Forma:SoildPeso molecular:346.38p-MPPI hydrochloride
CAS:<p>p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects.</p>Fórmula:C25H28ClIN4O2Pureza:99.95%Cor e Forma:SolidPeso molecular:578.87Fluoxetine
CAS:<p>Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.</p>Fórmula:C17H18F3NOPureza:99.07% - 99.28%Cor e Forma:SolidPeso molecular:309.33Promazine hydrochloride
CAS:<p>Promazine hydrochloride, a phenothiazine less potent than chlorpromazine, treats disturbed behavior and nausea.</p>Fórmula:C17H21ClN2SPureza:99.90%Cor e Forma:SolidPeso molecular:320.88Ziprasidone hydrochloride monohydrate
CAS:<p>Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic</p>Fórmula:C21H21ClN4OS·HCl·H2OPureza:98% - 99.83%Cor e Forma:Off-White PowderPeso molecular:467.12Azacyclonol
CAS:<p>Azacyclonol (MER 17) is a drug used to diminish hallucinations in psychotic individuals.</p>Fórmula:C18H21NOPureza:99.46%Cor e Forma:Solid PowderPeso molecular:267.37Zolmitriptan
CAS:<p>Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.</p>Fórmula:C16H21N3O2Pureza:99.69% - 99.91%Cor e Forma:White Or Kind Of White PowderPeso molecular:287.36Lafutidine
CAS:<p>Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.</p>Fórmula:C22H29N3O4SPureza:98.55%Cor e Forma:Yellowish White Crystalline PowderPeso molecular:431.55Cisapride
CAS:<p>Cisapride (R 51619), a 5-HT4 agonist, enhances gut peristalsis and gastric emptying, reduces reflux.</p>Fórmula:C23H29ClFN3O4Pureza:99.77%Cor e Forma:White To Slightly Biege Powder SolidPeso molecular:465.95Blonanserin
CAS:<p>Blonanserin (AD-5423), approved in Japan (2008), is an atypical antipsychotic with fewer side effects like EPS, sedation, or hypotension.</p>Fórmula:C23H30FN3Pureza:99.85%Cor e Forma:SolidPeso molecular:367.5Protriptyline hydrochloride
CAS:<p>Protriptyline HCl: a tricyclic antidepressant that increases norepinephrine and serotonin levels and has anticholinergic effects.</p>Fórmula:C19H21N·HClPureza:98.54% - 99.98%Cor e Forma:SolidPeso molecular:299.84Olanzapine
CAS:<p>Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.</p>Fórmula:C17H20N4SPureza:99.86% - ≥95%Cor e Forma:Yellowish Crystalline PowderPeso molecular:312.43Ketanserin
CAS:<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Fórmula:C22H22FN3O3Pureza:99.19% - 99.73%Cor e Forma:SolidPeso molecular:395.43Duloxetine hydrochloride
CAS:<p>Duloxetine hydrochloride is an SNRI used for depression, anxiety, and pain in diabetes and fibromyalgia.</p>Fórmula:C18H20ClNOSPureza:99.93% - >99.99%Cor e Forma:White Or White Crystalline PowderPeso molecular:333.88Azatadine dimaleate
CAS:<p>Azatadine dimaleate (SCH10649) is an inhibitor for histamine（IC50=6.5 nM） and cholinergic（IC50=10 nM）.</p>Fórmula:C28H30N2O8Pureza:99.7% - >99.99%Cor e Forma:PowderPeso molecular:522.55Talipexole dihydrochloride
CAS:<p>Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and</p>Fórmula:C10H17Cl2N3SPureza:99.89%Cor e Forma:Light Yellow SolidPeso molecular:282.234-Butyl-α-agarofuran
CAS:<p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>Fórmula:C18H30OCor e Forma:SolidPeso molecular:262.43ECPLA
CAS:<p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>Fórmula:C21H25N3OCor e Forma:SolidPeso molecular:335.44(+)-OSU 6162
CAS:<p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>Fórmula:C15H23NO2SPureza:98.19%Cor e Forma:SoildPeso molecular:281.41Minesapride
CAS:<p>Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.</p>Fórmula:C21H31ClN4O5Pureza:99.85% - 99.88%Cor e Forma:SolidPeso molecular:454.95Tiaspirone hydrochloride
CAS:<p>Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.</p>Fórmula:C24H33ClN4O2SPureza:99.87%Cor e Forma:SoildPeso molecular:477.06Tetrahydro-β-carboline
CAS:<p>Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C11H12N2Pureza:96.31%Cor e Forma:Tan SolidPeso molecular:172.22645-HT2C agonist-4
CAS:<p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>Fórmula:C24H25N5OCor e Forma:SolidPeso molecular:399.49N-Desmethyl Pimavanserin
CAS:<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Fórmula:C24H32FN3O2Pureza:98.02%Cor e Forma:SolidPeso molecular:413.53ALEPH hydrochloride
CAS:<p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>Fórmula:C12H20ClNO2SCor e Forma:SolidPeso molecular:277.81Mesoridazine Besylate
CAS:<p>Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.</p>Fórmula:C27H32N2O4S3Pureza:99.58%Cor e Forma:SolidPeso molecular:544.75SKF-83566 hydrochloride
CAS:<p>SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.</p>Fórmula:C17H19BrClNOPureza:99.27%Cor e Forma:SoildPeso molecular:368.69(R)-Citalopram oxalate
CAS:<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Fórmula:C22H23FN2O5Pureza:99.76%Cor e Forma:White SolidPeso molecular:414.43Femoxetine
CAS:<p>Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.</p>Fórmula:C20H25NO2Pureza:99.1% - 99.35%Cor e Forma:SolidPeso molecular:311.42GM-60186
<p>GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.</p>Fórmula:C30H33FN2O4Cor e Forma:SolidPeso molecular:504.595-MeO-pyr-T
CAS:<p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>Fórmula:C15H20N2OCor e Forma:SolidPeso molecular:244.33Tabernanthalog
CAS:<p>TBG is a 5-HT2A agonist reducing alcohol/heroin cravings and promoting neuroplasticity with antidepressant effects in rodents.</p>Fórmula:C14H18N2OPureza:99.82% - 99.89%Cor e Forma:SoildPeso molecular:230.31Paynantheine
CAS:<p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>Fórmula:C23H28N2O4Cor e Forma:SolidPeso molecular:396.48AMI-193
CAS:<p>AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.</p>Fórmula:C22H26FN3O2Pureza:99.65%Cor e Forma:SolidPeso molecular:383.46Sulamserod
CAS:<p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>Fórmula:C19H28ClN3O5SPureza:98.76%Cor e Forma:SolidPeso molecular:445.96Dapoxetine
CAS:<p>Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.</p>Fórmula:C21H23NOPureza:99.73%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:305.42HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Fórmula:C35H43Cl2F2N5O4Cor e Forma:SolidPeso molecular:706.65(Rac)-Norcisapride
CAS:<p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>Fórmula:C14H20ClN3O3Pureza:99.32%Cor e Forma:SoildPeso molecular:313.78Cabergoline
CAS:<p>Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.</p>Fórmula:C26H37N5O2Pureza:97.69% - 99.86%Cor e Forma:White Crystalline SolidPeso molecular:451.65-HT1AR agonist 2
<p>5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.</p>Fórmula:C31H31N5O3Cor e Forma:SolidPeso molecular:521.615-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Fórmula:C24H26N4O2SCor e Forma:SolidPeso molecular:434.55NPS ALX Compound 4a hydrochloride(1:1)
<p>NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.</p>Fórmula:C25H26ClN3O2SPureza:99.84%Cor e Forma:SoildPeso molecular:468.015-HT1AR/5-HT6R ligand-1
<p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>Fórmula:C25H29ClN4O2SCor e Forma:SolidPeso molecular:485.04SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Fórmula:C25H30ClN3O3SCor e Forma:SolidPeso molecular:488.04Dehydro Aripiprazole (hydrochloride)
CAS:<p>Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.</p>Fórmula:C23H26Cl3N3O2Cor e Forma:SolidPeso molecular:482.83Tryptamine hydrochloride
CAS:<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Fórmula:C10H13ClN2Pureza:99.89%Cor e Forma:SolidPeso molecular:196.68Mosapride citrate dihydrate
CAS:<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Fórmula:C27H35ClFN3O11Pureza:98%Cor e Forma:SolidPeso molecular:632.04LE 300
CAS:<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Fórmula:C20H22N2Pureza:97.91% - 98.79%Cor e Forma:SolidPeso molecular:290.4(Iso)-Landipirdine
CAS:<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Fórmula:C18H19FN2O3SPureza:98.50%Cor e Forma:SoildPeso molecular:362.42Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Fórmula:C17H19N3OCor e Forma:SolidPeso molecular:281.359Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.41isomer-Cilansetron
CAS:<p>isomer-Cilansetron is an isomer of Cilansetron.</p>Fórmula:C20H21N3OPureza:99.92% - 99.96%Cor e Forma:SoildPeso molecular:319.45-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Fórmula:C13H18N2OPureza:98.25%Cor e Forma:SolidPeso molecular:218.29Xaliproden
CAS:<p>Xaliproden is a biochemical.</p>Fórmula:C24H22F3NCor e Forma:SolidPeso molecular:381.43LY-53857 free base
CAS:<p>LY-53857 free base is a bioactive chemical.</p>Fórmula:C23H32N2O3Cor e Forma:SolidPeso molecular:384.51Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Fórmula:C18H19N3OCor e Forma:SolidPeso molecular:293.37Cannabidiolic acid methyl ester
CAS:<p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>Fórmula:C23H32O4Cor e Forma:SolidPeso molecular:372.5Quetiapine-d4 fumarate
CAS:<p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>Fórmula:C25H29N3O6SPureza:98%Cor e Forma:SolidPeso molecular:503.61Desmethyl Mirtazapine (hydrochloride)
CAS:<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Fórmula:C16H18ClN3Cor e Forma:SolidPeso molecular:287.79SB 699551
CAS:<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Fórmula:C34H45N3OPureza:99.83%Peso molecular:511.74Nemifitide diTFA
CAS:<p>Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.</p>Fórmula:C37H45F7N10O10Pureza:99.78% - 99.84%Cor e Forma:SolidPeso molecular:922.8LEK 8804
CAS:<p>LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.</p>Fórmula:C19H19N3OCor e Forma:SolidPeso molecular:305.37Triazolomethylindole-3-acetic acid
CAS:<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Fórmula:C13H12N4O2Cor e Forma:SolidPeso molecular:256.26Isobutyryl-L-carnitine
CAS:<p>Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.</p>Fórmula:C11H21NO4Pureza:98%Cor e Forma:SolidPeso molecular:231.29MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Fórmula:C22H28ClN3O2Peso molecular:401.187(R,R)-Palonosetron Hydrochloride
CAS:<p>(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron</p>Fórmula:C19H25ClN2OPureza:98%Cor e Forma:SolidPeso molecular:332.87R 50595
CAS:<p>R 50595 is a selective non-competitive cisapride antagonist.</p>Fórmula:C30H35Cl2F2N3O3Pureza:98%Cor e Forma:SolidPeso molecular:594.52Cinanserin hydrochloride
CAS:<p>Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.</p>Fórmula:C20H25ClN2OSPureza:99.57%Cor e Forma:SolidPeso molecular:376.94Zalospirone
CAS:<p>Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.</p>Fórmula:C24H29N5O2Pureza:98.41% - 99.82%Cor e Forma:SolidPeso molecular:419.52DSP-1053
CAS:<p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>Fórmula:C26H32BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:502.44Peptide 401
CAS:<p>Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.</p>Fórmula:C110H192N40O24S4Pureza:98%Cor e Forma:SolidPeso molecular:2587.22Alverine hydrochloride
CAS:<p>Alverine hydrochloride is a parasympatholytic.</p>Fórmula:C20H28ClNCor e Forma:SolidPeso molecular:317.9Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Fórmula:C18H22N2SPureza:98%Cor e Forma:SolidPeso molecular:306.51,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Fórmula:C10H18OPureza:97.44% - 97.44%Cor e Forma:SolidPeso molecular:154.25Serazapine
CAS:<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Fórmula:C22H23N3O2Pureza:98.71% - 99.57%Cor e Forma:SolidPeso molecular:361.44Donitriptan hydrochloride
CAS:<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Fórmula:C23H26ClN5O2Pureza:99.8% - 99.86%Cor e Forma:SolidPeso molecular:439.94Zicronapine fumarate
CAS:<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Fórmula:C26H31ClN2O4Cor e Forma:SolidPeso molecular:470.99Alosetron
CAS:<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Fórmula:C17H18N4OPureza:98%Cor e Forma:Crystalline PowderPeso molecular:294.362-Methyl-N,N-dimethyltryptamine
CAS:<p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>Fórmula:C13H18N2Cor e Forma:SolidPeso molecular:202.3Neocarzinostatin
CAS:<p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>Pureza:98%Cor e Forma:SolidPeso molecular:N/ASB 216641
CAS:<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Fórmula:C28H30N4O4Pureza:98.09%Cor e Forma:SolidPeso molecular:486.56Cianopramine hydrochloride
CAS:<p>Cianopramine hydrochloride is a bio-active chemical.</p>Fórmula:C20H24ClN3Cor e Forma:SolidPeso molecular:341.88AL 34662
CAS:<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Fórmula:C10H13N3OPureza:99.77%Cor e Forma:SolidPeso molecular:191.23Lisuride maleate
CAS:<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Fórmula:C24H30N4O5Pureza:99.85%Cor e Forma:SolidPeso molecular:454.52BMY-14802
CAS:<p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>Fórmula:C18H22F2N4OPureza:99.84%Cor e Forma:SoildPeso molecular:348.39Pellotine
CAS:<p>Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.</p>Fórmula:C13H19NO3Cor e Forma:SolidPeso molecular:237.2955-HT2A receptor agonist-5
CAS:<p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>Fórmula:C23H29N3OCor e Forma:SolidPeso molecular:363.5Asenapine citrate
CAS:<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Fórmula:C23H24ClNO8Cor e Forma:SolidPeso molecular:477.895-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Fórmula:C25H30N4O2SCor e Forma:SolidPeso molecular:450.6Minaprine
CAS:<p>Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.</p>Fórmula:C17H22N4OPureza:98%Cor e Forma:SolidPeso molecular:298.38pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Fórmula:C10H13Cl2NO2Pureza:99.73% - 99.88%Cor e Forma:SolidPeso molecular:250.12Galanin (1-15) (porcine, rat)
CAS:<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Fórmula:C72H105N19O20Pureza:98%Cor e Forma:SolidPeso molecular:1556.72
