Beta Amilóide
Os inibidores de beta-amiloide são compostos que visam especificamente inibir a formação ou agregação de peptídeos beta-amiloides, que desempenham um papel crítico na patogênese da doença de Alzheimer. O acúmulo de placas de beta-amiloide no cérebro é uma característica marcante da doença, levando à disfunção neuronal e ao declínio cognitivo. Ao impedir a agregação de beta-amiloide, esses inibidores estão sendo explorados como potenciais agentes terapêuticos para retardar ou prevenir a progressão da doença de Alzheimer. Na CymitQuimica, oferecemos uma variedade de inibidores de beta-amiloide de alta qualidade para apoiar sua pesquisa em neurodegeneração, agregação de proteínas e terapia para Alzheimer.
Foram encontrados 276 produtos para "Beta Amilóide".
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Donanemab
CAS:Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.Pureza:95%Cor e Forma:Transparent LiquidPeso molecular:145.36 kDa (Predicted)Chlorzoxazone
CAS:Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.Fórmula:C7H4ClNO2Pureza:99.49% - 99.6%Cor e Forma:White SolidPeso molecular:169.565Lecanemab
CAS:Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated beta amyloid (Abeta) for the study of cognitive disorders.Pureza:95% - >95.0% (SDS-PAGE); 100% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:147.06 kDa (Predicted)LY 2389575 hydrochloride
CAS:LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.Fórmula:C15H16BrCl3N4Pureza:99.9%Cor e Forma:SolidPeso molecular:438.58Glimepiride
CAS:Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.Fórmula:C24H34N4O5SPureza:97.84% - 98.87%Cor e Forma:White SolidPeso molecular:490.62Methoxy-X04
CAS:Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).Fórmula:C23H20O3Pureza:98.96%Cor e Forma:SolidPeso molecular:344.4Eprodisate disodium
CAS:Eprodisate disodium (NC-503) is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.Fórmula:C3H6Na2O6S2Pureza:99.88%Cor e Forma:SolidPeso molecular:248.19Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Fórmula:C23H14Na2O11Pureza:99.4% - 99.95%Cor e Forma:White SolidPeso molecular:512.33Birtamimab
CAS:Birtamimab (NEOD001) is a monoclonal antibody selectively targeting and depleting amyloid protein, used in research on light chain amyloidosis.Pureza:>95%Cor e Forma:Transparent LiquidPeso molecular:146.44 kDa (Predicted)Gantenerumab
CAS:Gantenerumab (R-1450) is a humanized antibody targeting amyloid-β (Aβ), used in studies of Alzheimer's disease.Pureza:>95%Cor e Forma:Transparent LiquidPeso molecular:146.28 kDa (Predicted)ALZ-801
CAS:ALZ-801, an oral valine-prodrug of tramiprosate, enhances treatment of Alzheimer's by inhibiting β-amyloid aggregation with better PK and tolerance.Fórmula:C8H18N2O4SPureza:99.36%Cor e Forma:SolidPeso molecular:238.305QSH peptide
CAS:The QSH peptide is a polypeptide that specifically binds to Aβ1-42, and is employed in the synthesis of siRNA delivery complexes. It is applicable in research related to Alzheimer's disease (AD).Fórmula:C62H95N21O18Cor e Forma:SolidPeso molecular:1422.55Nivegacetor
CAS:Nivegacetor(RG6289) is a selective and orally administrable γ-secretase regulator that can affect the production of amyloid-β in cerebrospinal fluid.Fórmula:C23H25F2N7O2Pureza:99.84%Cor e Forma:Yellow SolidPeso molecular:469.49β-Amyloid (12-28) (TFA)
β-Amyloid (12-28) (TFA), a peptide fragment of the β-amyloid protein (β1-42)—a 42 amino acid protein primarily found in senile plaque cores—exhibits aggregationFórmula:C91H136N25F3O27Cor e Forma:SolidPeso molecular:2069.25-TAMRA-Amyloid β-Protein (1-40)
CAS:5-TAMRA-Amyloid β-Protein (1-40) is a TAMRA-labeled variant of Amyloid β-Protein (1-40), featuring an absorption/emission spectrum at 544/572 nm [1].Cor e Forma:Solid(Pyr3)-Amyloid β-Protein (3-42)
CAS:(Pyr3)-Amyloid β-Protein (3-42) is the predominant amyloid β peptide structure found deposited in the brains of individuals with Alzheimer's disease and Down syndrome. It is thought that (Pyr3)-Amyloid β-Protein (3-42) accumulates in the brain, leading to the formation of insoluble amyloid β-peptide deposits.Fórmula:C196H299N53O55SCor e Forma:SolidPeso molecular:4307.19498(Gly22)-amyloid β-protein(1-40)
CAS:Amyloid beta-protein(1-40) Arctic variant (Ab40ARC (E22G)), featuring a glycine at position 22 (Gly22), is a peptide utilized in Alzheimer's disease research [1Cor e Forma:Solidβ Amyloid(28-35) human
CAS:β-Amyloid(28-35) human is a neurotoxic β-amyloid peptide fragment that contributes to Alzheimer's disease pathogenesis by interacting with neuronal membranes,Fórmula:C36H67N9O9SCor e Forma:SolidPeso molecular:802.04p-HTAA
CAS:p-HTAA is a pentamer thiopheneacetic acid labeling Aβ deposits, used in amyloid research.Fórmula:C24H16O4S5Pureza:98.68% - 99.09%Cor e Forma:Yellow SolidPeso molecular:528.71Amilo-5MER sodium salt
Amilo-5MER sodium salt is an oral SAA inhibitor that reduces IL-6 and IL-1β release and is used in inflammation research.Fórmula:C23H39N6NaO9SPureza:99.28%Peso molecular:598.65
