Beta Amilóide
Os inibidores de beta-amiloide são compostos que visam especificamente inibir a formação ou agregação de peptídeos beta-amiloides, que desempenham um papel crítico na patogênese da doença de Alzheimer. O acúmulo de placas de beta-amiloide no cérebro é uma característica marcante da doença, levando à disfunção neuronal e ao declínio cognitivo. Ao impedir a agregação de beta-amiloide, esses inibidores estão sendo explorados como potenciais agentes terapêuticos para retardar ou prevenir a progressão da doença de Alzheimer. Na CymitQuimica, oferecemos uma variedade de inibidores de beta-amiloide de alta qualidade para apoiar sua pesquisa em neurodegeneração, agregação de proteínas e terapia para Alzheimer.
Foram encontrados 205 produtos de "Beta Amilóide"
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β-Amyloid (12-28)
CAS:<p>Amyloid β-peptide fragment; minimum section required to bind to brain proteins.</p>Fórmula:C89H135N25O25Pureza:98%Cor e Forma:SolidPeso molecular:1955.18AZD4694 Precursor
CAS:<p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>Fórmula:C22H25N3O7Cor e Forma:SolidPeso molecular:443.45RAGE antagonist peptide
CAS:<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Fórmula:C57H101N13O17SPureza:98%Cor e Forma:SolidPeso molecular:1272.56β-Amyloid (18-28)
CAS:<p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>Fórmula:C55H81N13O18Pureza:98%Cor e Forma:SolidPeso molecular:1212.31β-Amyloid (10-20)
CAS:<p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>Fórmula:C71H99N17O16Pureza:98%Cor e Forma:Lyophilized PowderPeso molecular:1446.65Sabirnetug
CAS:<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Cor e Forma:Liquidγ-Secretase Modulators
CAS:<p>gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.</p>Fórmula:C26H24F3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:483.48Davunetide
CAS:<p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>Fórmula:C36H60N10O12Pureza:98%Cor e Forma:SolidPeso molecular:824.92BIBD-124
CAS:<p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>Fórmula:C19H24FN3O3Cor e Forma:SolidPeso molecular:361.41SEN177
CAS:<p>SEN177 shows the potential in the research of Huntington's disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].</p>Fórmula:C18H19FN6Cor e Forma:SolidPeso molecular:338.38TH-237A
CAS:<p>TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.</p>Fórmula:C18H17F2NO3Pureza:98%Cor e Forma:SolidPeso molecular:333.335Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Fórmula:C9H8ClF6NO3S2Cor e Forma:SolidPeso molecular:391.74(Rac)-Z-Phe-Phe-FMK
CAS:<p>(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .</p>Fórmula:C27H27FN2O4Pureza:98.27%Cor e Forma:SolidPeso molecular:462.51AZD4694
CAS:<p>Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.</p>Fórmula:C14H11FN2O2Cor e Forma:SolidPeso molecular:258.25Cu(II)GTSM
CAS:<p>Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.</p>Fórmula:C6H10CuN6S2Pureza:99.21%Cor e Forma:SolidPeso molecular:293.86Pyridoxal 5'-phosphate hydrate
CAS:<p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>Fórmula:C8H10NO6PPureza:97.52%Cor e Forma:SolidPeso molecular:247.141,1'-Methylenedi-2-naphthol
CAS:<p>1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).</p>Fórmula:C21H16O2Pureza:98.91%Cor e Forma:Light Pink To Light Brown Crystalline PowderPeso molecular:300.35Miridesap
CAS:<p>Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.</p>Fórmula:C16H24N2O6Pureza:≥95%Cor e Forma:SolidPeso molecular:340.37PiB
CAS:<p>PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.</p>Fórmula:C14H12N2OSPureza:97.02%Cor e Forma:SolidPeso molecular:256.32CRANAD 2
CAS:<p>CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.</p>Fórmula:C23H25BF2N2O2Pureza:99.44%Cor e Forma:Dark Blue To Black PowderPeso molecular:410.27
