COX
Os inibidores da ciclooxigenase (COX) são compostos que bloqueiam a atividade das enzimas COX, envolvidas na produção de prostaglandinas, mediadores chave da inflamação e dor. Em neurociências, os inibidores de COX são estudados por seu potencial em reduzir a neuroinflamação, que está implicada em várias doenças neurodegenerativas, como a doença de Alzheimer, Parkinson e esclerose múltipla. Ao inibir a COX, esses compostos podem ajudar a mitigar os processos inflamatórios no cérebro e proteger contra danos neuronais. Na CymitQuimica, oferecemos uma variedade de inibidores de COX para apoiar sua pesquisa em neuroinflamação, gestão da dor e doenças neurodegenerativas.
Foram encontrados 562 produtos de "COX"
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K-80001
CAS:<p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>Fórmula:C20H17FO2Cor e Forma:SolidPeso molecular:308.35Anti-inflammatory agent 8
CAS:<p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>Fórmula:C18H15N5OS2Cor e Forma:SolidPeso molecular:381.47Apricoxib
CAS:<p>Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.</p>Fórmula:C19H20N2O3SCor e Forma:SolidPeso molecular:356.44COX-2/sEH-IN-1
CAS:<p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>Fórmula:C23H18F3N5O3SCor e Forma:SolidPeso molecular:501.48Naproxen glucuronide
CAS:<p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>Fórmula:C20H22O9Cor e Forma:SolidPeso molecular:406.38AL-8417
CAS:<p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>Fórmula:C29H34O5Pureza:98%Cor e Forma:SolidPeso molecular:462.58PD 127443
CAS:<p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>Fórmula:C20H28N2OCor e Forma:SolidPeso molecular:312.45COX-2-IN-32
CAS:<p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>Fórmula:C25H24O6Pureza:98%Cor e Forma:SolidPeso molecular:420.45Thiazolinobutazone
CAS:<p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>Fórmula:C22H26N4O2SCor e Forma:SolidPeso molecular:410.53ASP-6537
CAS:<p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>Fórmula:C17H17N3O3Pureza:98%Cor e Forma:SolidPeso molecular:311.34COX/5-LOX-IN-1
CAS:<p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>Fórmula:C18H30O3Cor e Forma:SolidPeso molecular:294.43Pifoxime
CAS:<p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>Fórmula:C15H20N2O3Cor e Forma:SolidPeso molecular:276.33COX-2-IN-16
CAS:<p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>Fórmula:C19H12BrN3O2Cor e Forma:SolidPeso molecular:394.22COX-2/5-LOX-IN-3
CAS:<p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>Fórmula:C17H16ClN3O2SCor e Forma:SolidPeso molecular:361.85ATB-337
CAS:<p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>Fórmula:C23H15Cl2NO2S3Cor e Forma:SolidPeso molecular:504.47Flosulide
CAS:<p>Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.</p>Fórmula:C16H13F2NO4SPureza:98%Cor e Forma:SolidPeso molecular:353.34AHR-6293
CAS:<p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>Fórmula:C15H12ClNO3Cor e Forma:SolidPeso molecular:289.71NCX 466
CAS:<p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>Fórmula:C20H24N2O9Pureza:98%Cor e Forma:SolidPeso molecular:436.41Etoricoxib HCl
CAS:<p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>Fórmula:C18H16Cl2N2O2SCor e Forma:SolidPeso molecular:395.30Lobeglitazone Sulfate
CAS:<p>Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.</p>Fórmula:C24H26N4O9S2Pureza:98.69%Cor e Forma:SolidPeso molecular:578.61
