CaMK
Os inibidores da Proteína Quinase Dependente de Cálcio/Calmodulina (CaMK) são compostos especializados que inibem a atividade da CaMK, uma quinase crucial envolvida em uma variedade de processos celulares, particularmente no sistema nervoso. A CaMK é essencial para traduzir sinais de cálcio em várias respostas celulares, incluindo a plasticidade sináptica, a formação de memória e a expressão gênica. A desregulação da atividade da CaMK está associada a vários distúrbios neurológicos, tornando esses inibidores ferramentas valiosas para o estudo da sinalização sináptica, do aprendizado e da memória. Na CymitQuimica, oferecemos inibidores de CaMK de alta qualidade para apoiar sua pesquisa em plasticidade sináptica, função cognitiva e neurofarmacologia.
Foram encontrados 69 produtos de "CaMK"
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Calmodulin-Dependent Protein Kinase II 290-309 acetate
<p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>Fórmula:C105H189N31O26SPureza:96.7%Cor e Forma:SolidPeso molecular:2333.88CALP2 TFA
<p>CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.</p>Fórmula:C70H105F3N14O15SCor e Forma:SolidPeso molecular:1471.72Syntide 2 TFA
Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.Fórmula:C70H123N20F3O20Cor e Forma:SolidPeso molecular:1621.84AC3-I, myristoylated
<p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>Fórmula:C78H137N21O20Pureza:98%Cor e Forma:SolidPeso molecular:1689.05Calmodulin Kinase IINtide, Myristoylated
<p>Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].</p>Fórmula:C156H275N47O43Pureza:98%Cor e Forma:SolidPeso molecular:3497.14CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Fórmula:C54H58Cl2N10O11Pureza:98%Cor e Forma:SolidPeso molecular:1094CAMKIV Protein, Human, Recombinant (GST)
CAMKIV Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.Cor e Forma:Lyophilized PowderPeso molecular:79 kDa (predicted); 100 kDa (reducing conditions)lavendustin C
CAS:<p>lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.</p>Fórmula:C14H13NO5Pureza:98.06%Cor e Forma:Yellow To Tan PowderPeso molecular:275.26KN-93
CAS:<p>KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.</p>Fórmula:C26H29ClN2O4SPureza:99.56% - 99.86%Cor e Forma:White SolidPeso molecular:501.04Trifluoperazine
CAS:<p>Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.</p>Fórmula:C21H24F3N3SPureza:98.3% - 99.46%Cor e Forma:White To Yellowish Crystalline PowderPeso molecular:407.5NH125
CAS:<p>NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.</p>Fórmula:C27H45IN2Pureza:98.60%Cor e Forma:SolidPeso molecular:524.56CALP1 acetate
<p>CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site.</p>Fórmula:C42H79N9O12Pureza:99.63%Cor e Forma:SolidPeso molecular:902.13Autocamtide-2-related inhibitory peptide
CAS:<p>Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.</p>Fórmula:C64H116N22O19Pureza:>99.99%Cor e Forma:SolidPeso molecular:1497.74Autocamtide 2 TFA(129198-88-5 free base)
<p>Autocamtide 2 TFA, selective CaMKII peptide substrate, used in its activity assay.</p>Fórmula:C67H119F3N22O22Pureza:98%Cor e Forma:SolidPeso molecular:1641.79CaMKII-IN-1
CAS:CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).Fórmula:C29H30ClN5O2SPureza:99.69%Cor e Forma:SolidPeso molecular:548.1Syntide 2 acetate(108334-68-5 free base)
<p>Syntide-2 acetate is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 μM).</p>Fórmula:C70H126N20O20Pureza:99.74%Cor e Forma:SolidPeso molecular:1567.85KN-92 hydrochloride
CAS:<p>KN-92 hydrochloride is an inactive derivative of KN-93.</p>Fórmula:C24H26Cl2N2O3SPureza:99.68%Cor e Forma:SolidPeso molecular:493.45A-484954
CAS:<p>A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.</p>Fórmula:C13H15N5O3Pureza:97.47% - 99.86%Cor e Forma:SolidPeso molecular:289.29CaM kinase II inhibitor TFA salt
<p>CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.</p>Fórmula:C66H117F3N22O21Pureza:>99.99%Cor e Forma:SolidPeso molecular:1611.77STO-609
CAS:<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Fórmula:C19H10N2O3Pureza:97.14% - 98.8%Cor e Forma:SolidPeso molecular:314.29
